PhysioNet is a global platform for biomedical research and an NIH-funded publishing platform for rigorously curated, de-identified biomedical and clinical data, software, machine-learning models, and educational resources. Originally established in 1999 as the outreach component of the NIH Research Resource for Complex Physiologic Signals, PhysioNet has evolved from a repository centered on physiological waveforms into an integrated, community-driven framework for publishing, accessing, and reusing biomedical data and software. Its mission remains to make biomedical and clinical datasets freely available to the life-science research community, and to promote, enable, and catalyze reproducible, data-driven research with tangible clinical impact.

The PhysioNet platform is managed by the MIT Laboratory for Computational Physiology with support from the global research community. Research and educational activities in complex physiologic signal analysis is also carried out by the Margret and H.A. Rey Institute for Nonlinear Dynamics at Beth Israel Deaconess Medical Center.

PhysioNet traces its origins to the creation of the MIT-BIH Arrhythmia Database in the late 1970s, one of the earliest broadly shared benchmark datasets for evaluating arrhythmia detection algorithms. Together with other foundational ECG databases, it helped establish standards for transparent evaluation, shared test data, and objective comparison of biomedical signal-processing methods.

In 1999, Roger Mark and George Moody at MIT, together with Ary Goldberger at Beth Israel Deaconess Medical Center and Eugene Stanley at Boston University, founded the NIH Research Resource for Complex Physiologic Signals. At its founding, the resource unified PhysioBank, a repository of curated datasets; PhysioToolkit, open-source analysis software; and the PhysioNet web portal, which provided a shared environment for reproducible research. Over time these components became deeply intertwined, and in 2019 the distinctions between them were retired as the platform was consolidated under the single name PhysioNet.

What began as a small signal-processing archive has grown into a global platform supporting biomedical research across disciplines, from physiological signal processing and critical care to clinical informatics and translational AI. For more background, see: https://jclinic.mit.edu/physionet-at-25/

PhysioNet was originally established under the NIH National Center for Research Resources (NCRR). Current support comes from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the National Heart, Lung, and Blood Institute (NHLBI), and the NIH Office of the Director under grant numbers U24EB037545 and R01EB030362.

If you use data or software from PhysioNet in a publication, please credit the author(s) when referencing it. You can find authors' names, and in many cases their publications introducing the data or software, on the project pages for their contributions. Please also include the citation for PhysioNet:

Pollard T, Moody BE, Lehman L, Gow B, Fernandes C, Xie C, Johnson A, Mark RG, Heldt T. PhysioNet as a Global Platform for Biomedical Research. Nature Health (2026). https://doi.org/10.1038/s44360-026-00096-z. Available from: https://rdcu.be/faatM

You may also site the following paper:

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation 101(23):e215-e220 [Circulation Electronic Pages; http://circ.ahajournals.org/content/101/23/e215.full]; 2000 (June 13).

PhysioNet is maintained by researchers and engineers at the MIT Laboratory for Computational Physiology. To reach us, email contact@physionet.org.