-
Mr.Dec: Daily-Scale Longitudinal Multimodal Modeling for 30-Day Readmission Prediction
Authors:
Minjun Kim,
Jong Hak Moon
Abstract:
Predicting 30-day hospital readmission is essential for assessing patient stability and optimizing healthcare resources. As clinical risk evolves with the accumulation of evidence during hospitalization, capturing these dynamic trajectories is essential. However, many existing approaches compress the complex longitudinal history into fixed representations, often losing the granular, day-level clin…
▽ More
Predicting 30-day hospital readmission is essential for assessing patient stability and optimizing healthcare resources. As clinical risk evolves with the accumulation of evidence during hospitalization, capturing these dynamic trajectories is essential. However, many existing approaches compress the complex longitudinal history into fixed representations, often losing the granular, day-level clinical signals that reflect a patient's evolving physiological state. To address this, we propose Mr.Dec (Multimodal Readmission-risk prediction Decoder), which models each admission as a natural chronological sequence of daily multimodal events. By leveraging a Transformer Decoder, Mr.Dec integrates daily Electronic Health Record(EHR) updates and intermittent Chest X-ray(CXR) findings in a time-aligned stream, reflecting the actual clinical workflow. To ensure robustness, we utilize Disease-Specific Supervised Contrastive Learning as an auxiliary regularization to induce a diagnosis-aware structure in the latent space. Evaluations on the MIMIC-IV and MIMIC-CXR datasets show that Mr.Dec achieves state-of-the-art performance by preserving the integrity of the clinical sequence. Furthermore, our model identifies "Critical Days" within an admission, providing actionable and clinically grounded interpretations for real-time risk stratification. Code is available at: https://github.com/yejix-ai/MR.DEC
△ Less
Submitted 5 August, 2026;
originally announced August 2026.
-
Clinically-Grounded Hierarchical Classification for Consistent Chest X-ray Interpretation
Authors:
Jong Hak Moon,
Minjun Kim,
Minjun Kim
Abstract:
Accurate chest X-ray interpretation is inherently hierarchical. Clinical decisions depend not only on what abnormality is present but where it is situated, requiring reasoning from broad anatomical systems down to specific pathological findings. Yet existing automated systems largely treat this as a flat classification problem, failing to capture inter-level dependencies or enforce coherence betwe…
▽ More
Accurate chest X-ray interpretation is inherently hierarchical. Clinical decisions depend not only on what abnormality is present but where it is situated, requiring reasoning from broad anatomical systems down to specific pathological findings. Yet existing automated systems largely treat this as a flat classification problem, failing to capture inter-level dependencies or enforce coherence between coarse and fine predictions. We propose CHASE (Classification with Hierarchical Analysis and Structured Enforcement), a unified single-stage framework that mirrors radiologists' coarse-to-fine reasoning through a clinically driven three-level taxonomy of 9 anatomical regions, 17 sub-regions, and 28 pathological findings. CHASE jointly optimizes multi-level supervision, cross-level probability alignment, and a hierarchy-violation penalty within a shared Vision Transformer backbone. This ensures that fine-grained findings are anatomically supported by their coarser-level context rather than predicted in isolation. Experiments demonstrate that CHASE outperforms flat and hierarchical baselines across all levels while achieving superior probabilistic hierarchy consistency, with level-wise attention maps confirming anatomically grounded predictions. Code is available at: https://github.com/yejix-ai/CHASE.
△ Less
Submitted 3 August, 2026;
originally announced August 2026.
-
EHRNote-ChatQA: A Benchmark for Evidence-Grounded Multi-Turn Clinical Question Answering over Longitudinal Discharge Summaries
Authors:
Jiyoun Kim,
Muhan Yeo,
Eunhye Jang,
Jeewon Yang,
Hangyul Yoon,
Su Ji Lee,
Hee Jo Han,
Hee-Jae Jung,
Doyun Kwon,
Jun young Lee,
Jaehun Lee,
Jung-Oh Lee,
Sunjun Kweon,
Jong Hak Moon,
Daseul Kim,
Minjae Cho,
Edward Choi
Abstract:
Discharge summaries are crucial clinical documents containing the context of a patient's overall hospital stay, and are routinely reviewed by medical experts for patient readmission, ongoing care, and diagnostic decision-making. When reviewing them, medical experts often must iteratively synthesize information across multiple summaries while verifying the evidence supporting each answer. Although…
▽ More
Discharge summaries are crucial clinical documents containing the context of a patient's overall hospital stay, and are routinely reviewed by medical experts for patient readmission, ongoing care, and diagnostic decision-making. When reviewing them, medical experts often must iteratively synthesize information across multiple summaries while verifying the evidence supporting each answer. Although large language models (LLMs) are increasingly explored for clinical question answering, existing benchmarks do not sufficiently reflect this setting: they often evaluate exam-style medical knowledge or focus on single-turn question answering with limited evidence-grounding evaluation. We introduce EHRNote-ChatQA, the first benchmark for evidence-grounded multi-turn clinical question answering over patients' multiple discharge summaries. Built from de-identified MIMIC-IV discharge summaries, EHRNote-ChatQA contains 967 patient-level multi-turn samples spanning one to five notes and 16,072 medical-expert-verified QA pairs (8,036 content questions, each paired with an evidence-grounding question) across eight clinical categories. The benchmark is constructed through an expert-informed pipeline combining discharge-summary structuring schema, expert-curated multi-turn QA templates, and LLM-based generation, followed by review and revision of every single QA sample by 11 medical experts. Benchmarking 22 open- and closed-source LLMs reveals several challenges, including that LLMs struggle more with evidence grounding than content answering, multi-turn errors compound across turns, and single-turn clinical QA performance does not reliably transfer to this setting. These findings establish EHRNote-ChatQA as a rigorous and practical benchmark for evaluating clinical QA systems. The dataset will be made publicly available through PhysioNet credentialed access.
△ Less
Submitted 16 June, 2026; v1 submitted 14 June, 2026;
originally announced June 2026.
-
Modeling Clinical Uncertainty in Radiology Reports: from Explicit Uncertainty Markers to Implicit Reasoning Pathways
Authors:
Paloma Rabaey,
Jong Hak Moon,
Jung-Oh Lee,
Min Gwan Kim,
Hangyul Yoon,
Thomas Demeester,
Edward Choi
Abstract:
Radiology reports are invaluable for clinical decision-making and hold great potential for automated analysis when structured into machine-readable formats. These reports often contain uncertainty, which we categorize into two distinct types: (i) Explicit uncertainty reflects doubt about the presence or absence of findings, conveyed through hedging phrases. These vary in meaning depending on the c…
▽ More
Radiology reports are invaluable for clinical decision-making and hold great potential for automated analysis when structured into machine-readable formats. These reports often contain uncertainty, which we categorize into two distinct types: (i) Explicit uncertainty reflects doubt about the presence or absence of findings, conveyed through hedging phrases. These vary in meaning depending on the context, making rule-based systems insufficient to quantify the level of uncertainty for specific findings; (ii) Implicit uncertainty arises when radiologists omit parts of their reasoning, recording only key findings or diagnoses. Here, it is often unclear whether omitted findings are truly absent or simply unmentioned for brevity. We address these challenges with a two-part framework. We quantify explicit uncertainty by creating an expert-validated, LLM-based reference ranking of common hedging phrases, and mapping each finding to a probability value based on this reference. In addition, we model implicit uncertainty through an expansion framework that systematically adds characteristic sub-findings derived from expert-defined diagnostic pathways for 14 common diagnoses. Using these methods, we release Lunguage++, an expanded, uncertainty-aware version of the Lunguage benchmark of fine-grained structured radiology reports. This enriched resource enables uncertainty-aware image classification, faithful diagnostic reasoning, and new investigations into the clinical impact of diagnostic uncertainty.
△ Less
Submitted 27 February, 2026; v1 submitted 6 November, 2025;
originally announced November 2025.
-
Lunguage: A Benchmark for Structured and Sequential Chest X-ray Interpretation
Authors:
Jong Hak Moon,
Geon Choi,
Paloma Rabaey,
Min Gwan Kim,
Jung-Oh Lee,
Hyuk Gi Hong,
Eun Woo Doe,
Hangyul Yoon,
Jiyoun Kim,
Harshita Sharma,
Daniel C. Castro,
Javier Alvarez-Valle,
Edward Choi
Abstract:
Radiology reports convey detailed clinical observations and capture diagnostic reasoning that evolves over time. However, existing evaluation methods are limited to single-report settings and rely on coarse metrics that fail to capture fine-grained clinical semantics and temporal dependencies. We introduce LUNGUAGE, a benchmark dataset for structured radiology report generation that supports both…
▽ More
Radiology reports convey detailed clinical observations and capture diagnostic reasoning that evolves over time. However, existing evaluation methods are limited to single-report settings and rely on coarse metrics that fail to capture fine-grained clinical semantics and temporal dependencies. We introduce LUNGUAGE, a benchmark dataset for structured radiology report generation that supports both single-report evaluation and longitudinal patient-level assessment across multiple studies. It contains 1,473 annotated chest X-ray reports, each reviewed by experts, and 186 of them contain longitudinal annotations to capture disease progression and inter-study intervals, also reviewed by experts. Using this benchmark, we develop a two-stage structuring framework that transforms generated reports into fine-grained, schema-aligned structured reports, enabling longitudinal interpretation. We also propose LUNGUAGESCORE, an interpretable metric that compares structured outputs at the entity, relation, and attribute level while modeling temporal consistency across patient timelines. These contributions establish the first benchmark dataset, structuring framework, and evaluation metric for sequential radiology reporting, with empirical results demonstrating that LUNGUAGESCORE effectively supports structured report evaluation. The code is available at: https://github.com/SuperSupermoon/Lunguage
△ Less
Submitted 28 April, 2026; v1 submitted 27 May, 2025;
originally announced May 2025.
-
Publicly Shareable Clinical Large Language Model Built on Synthetic Clinical Notes
Authors:
Sunjun Kweon,
Junu Kim,
Jiyoun Kim,
Sujeong Im,
Eunbyeol Cho,
Seongsu Bae,
Jungwoo Oh,
Gyubok Lee,
Jong Hak Moon,
Seng Chan You,
Seungjin Baek,
Chang Hoon Han,
Yoon Bin Jung,
Yohan Jo,
Edward Choi
Abstract:
The development of large language models tailored for handling patients' clinical notes is often hindered by the limited accessibility and usability of these notes due to strict privacy regulations. To address these challenges, we first create synthetic large-scale clinical notes using publicly available case reports extracted from biomedical literature. We then use these synthetic notes to train…
▽ More
The development of large language models tailored for handling patients' clinical notes is often hindered by the limited accessibility and usability of these notes due to strict privacy regulations. To address these challenges, we first create synthetic large-scale clinical notes using publicly available case reports extracted from biomedical literature. We then use these synthetic notes to train our specialized clinical large language model, Asclepius. While Asclepius is trained on synthetic data, we assess its potential performance in real-world applications by evaluating it using real clinical notes. We benchmark Asclepius against several other large language models, including GPT-3.5-turbo and other open-source alternatives. To further validate our approach using synthetic notes, we also compare Asclepius with its variants trained on real clinical notes. Our findings convincingly demonstrate that synthetic clinical notes can serve as viable substitutes for real ones when constructing high-performing clinical language models. This conclusion is supported by detailed evaluations conducted by both GPT-4 and medical professionals. All resources including weights, codes, and data used in the development of Asclepius are made publicly accessible for future research. (https://github.com/starmpcc/Asclepius)
△ Less
Submitted 29 July, 2024; v1 submitted 1 September, 2023;
originally announced September 2023.
-
Correlation between Alignment-Uniformity and Performance of Dense Contrastive Representations
Authors:
Jong Hak Moon,
Wonjae Kim,
Edward Choi
Abstract:
Recently, dense contrastive learning has shown superior performance on dense prediction tasks compared to instance-level contrastive learning. Despite its supremacy, the properties of dense contrastive representations have not yet been carefully studied. Therefore, we analyze the theoretical ideas of dense contrastive learning using a standard CNN and straightforward feature matching scheme rather…
▽ More
Recently, dense contrastive learning has shown superior performance on dense prediction tasks compared to instance-level contrastive learning. Despite its supremacy, the properties of dense contrastive representations have not yet been carefully studied. Therefore, we analyze the theoretical ideas of dense contrastive learning using a standard CNN and straightforward feature matching scheme rather than propose a new complex method. Inspired by the analysis of the properties of instance-level contrastive representations through the lens of alignment and uniformity on the hypersphere, we employ and extend the same lens for the dense contrastive representations to analyze their underexplored properties. We discover the core principle in constructing a positive pair of dense features and empirically proved its validity. Also, we introduces a new scalar metric that summarizes the correlation between alignment-and-uniformity and downstream performance. Using this metric, we study various facets of densely learned contrastive representations such as how the correlation changes over single- and multi-object datasets or linear evaluation and dense prediction tasks. The source code is publicly available at: https://github.com/SuperSupermoon/DenseCL-analysis
△ Less
Submitted 17 October, 2022;
originally announced October 2022.
-
Unified Simultaneous Wireless Information and Power Transfer for IoT: Signaling and Architecture with Deep Learning Adaptive Control
Authors:
Jong Jin Park,
Jong Ho Moon,
Hyeon Ho Jang,
Dong In Kim
Abstract:
In this paper, we propose a unified SWIPT signal and its architecture design in order to take advantage of both single tone and multi-tone signaling by adjusting only the power allocation ratio of a unified signal. For this, we design a novel unified and integrated receiver architecture for the proposed unified SWIPT signaling, which consumes low power with an envelope detection. To relieve the co…
▽ More
In this paper, we propose a unified SWIPT signal and its architecture design in order to take advantage of both single tone and multi-tone signaling by adjusting only the power allocation ratio of a unified signal. For this, we design a novel unified and integrated receiver architecture for the proposed unified SWIPT signaling, which consumes low power with an envelope detection. To relieve the computational complexity of the receiver, we propose an adaptive control algorithm by which the transmitter adjusts the communication mode through temporal convolutional network (TCN) based asymmetric processing. To this end, the transmitter optimizes the modulation index and power allocation ratio in short-term scale while updating the mode switching threshold in long-term scale. We demonstrate that the proposed unified SWIPT system improves the achievable rate under the self-powering condition of low-power IoT devices. Consequently it is foreseen to effectively deploy low-power IoT networks that concurrently supply both information and energy wirelessly to the devices by using the proposed unified SWIPT and adaptive control algorithm in place at the transmitter side.
△ Less
Submitted 25 June, 2021;
originally announced June 2021.
-
Multi-modal Understanding and Generation for Medical Images and Text via Vision-Language Pre-Training
Authors:
Jong Hak Moon,
Hyungyung Lee,
Woncheol Shin,
Young-Hak Kim,
Edward Choi
Abstract:
Recently a number of studies demonstrated impressive performance on diverse vision-language multi-modal tasks such as image captioning and visual question answering by extending the BERT architecture with multi-modal pre-training objectives. In this work we explore a broad set of multi-modal representation learning tasks in the medical domain, specifically using radiology images and the unstructur…
▽ More
Recently a number of studies demonstrated impressive performance on diverse vision-language multi-modal tasks such as image captioning and visual question answering by extending the BERT architecture with multi-modal pre-training objectives. In this work we explore a broad set of multi-modal representation learning tasks in the medical domain, specifically using radiology images and the unstructured report. We propose Medical Vision Language Learner (MedViLL), which adopts a BERT-based architecture combined with a novel multi-modal attention masking scheme to maximize generalization performance for both vision-language understanding tasks (diagnosis classification, medical image-report retrieval, medical visual question answering) and vision-language generation task (radiology report generation). By statistically and rigorously evaluating the proposed model on four downstream tasks with three radiographic image-report datasets (MIMIC-CXR, Open-I, and VQA-RAD), we empirically demonstrate the superior downstream task performance of MedViLL against various baselines, including task-specific architectures. The source code is publicly available at: https://github.com/SuperSupermoon/MedViLL
△ Less
Submitted 21 September, 2022; v1 submitted 24 May, 2021;
originally announced May 2021.
-
Few-shot Image Recognition with Manifolds
Authors:
Debasmit Das,
J. H. Moon,
C. S. George Lee
Abstract:
In this paper, we extend the traditional few-shot learning (FSL) problem to the situation when the source-domain data is not accessible but only high-level information in the form of class prototypes is available. This limited information setup for the FSL problem deserves much attention due to its implication of privacy-preserving inaccessibility to the source-domain data but it has rarely been a…
▽ More
In this paper, we extend the traditional few-shot learning (FSL) problem to the situation when the source-domain data is not accessible but only high-level information in the form of class prototypes is available. This limited information setup for the FSL problem deserves much attention due to its implication of privacy-preserving inaccessibility to the source-domain data but it has rarely been addressed before. Because of limited training data, we propose a non-parametric approach to this FSL problem by assuming that all the class prototypes are structurally arranged on a manifold. Accordingly, we estimate the novel-class prototype locations by projecting the few-shot samples onto the average of the subspaces on which the surrounding classes lie. During classification, we again exploit the structural arrangement of the categories by inducing a Markov chain on the graph constructed with the class prototypes. This manifold distance obtained using the Markov chain is expected to produce better results compared to a traditional nearest-neighbor-based Euclidean distance. To evaluate our proposed framework, we have tested it on two image datasets - the large-scale ImageNet and the small-scale but fine-grained CUB-200. We have also studied parameter sensitivity to better understand our framework.
△ Less
Submitted 22 October, 2020;
originally announced October 2020.
-
Multi-step Online Unsupervised Domain Adaptation
Authors:
J. H. Moon,
Debasmit Das,
C. S. George Lee
Abstract:
In this paper, we address the Online Unsupervised Domain Adaptation (OUDA) problem, where the target data are unlabelled and arriving sequentially. The traditional methods on the OUDA problem mainly focus on transforming each arriving target data to the source domain, and they do not sufficiently consider the temporal coherency and accumulative statistics among the arriving target data. We propose…
▽ More
In this paper, we address the Online Unsupervised Domain Adaptation (OUDA) problem, where the target data are unlabelled and arriving sequentially. The traditional methods on the OUDA problem mainly focus on transforming each arriving target data to the source domain, and they do not sufficiently consider the temporal coherency and accumulative statistics among the arriving target data. We propose a multi-step framework for the OUDA problem, which institutes a novel method to compute the mean-target subspace inspired by the geometrical interpretation on the Euclidean space. This mean-target subspace contains accumulative temporal information among the arrived target data. Moreover, the transformation matrix computed from the mean-target subspace is applied to the next target data as a preprocessing step, aligning the target data closer to the source domain. Experiments on four datasets demonstrated the contribution of each step in our proposed multi-step OUDA framework and its performance over previous approaches.
△ Less
Submitted 20 February, 2020;
originally announced February 2020.