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GraphVid: Interactive Graph-Controllable Video Generation
Authors:
Vedant Shah,
Onkar Susladkar,
Tushar Prakash,
Kiet Nguyen,
Tianjio Yu,
Adheesh Juvekar,
Muntasir Waheed,
Ismini Lourentzou
Abstract:
Controllable video generation remains challenging due to the difficulty of specifying precise multi-object interactions using text prompts or motion-control inputs that primarily constrain pixel movement. In practice, trajectory-based control often requires users to draw accurate tracks for multiple objects, which scales poorly with scene complexity and becomes ambiguous under occlusion or overlap…
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Controllable video generation remains challenging due to the difficulty of specifying precise multi-object interactions using text prompts or motion-control inputs that primarily constrain pixel movement. In practice, trajectory-based control often requires users to draw accurate tracks for multiple objects, which scales poorly with scene complexity and becomes ambiguous under occlusion or overlap. To enable flexible yet precise multi-subject control, we introduce $\textbf{GraphVid}$, a graph-conditioned image-to-video generation model that enables interactive control through structured interaction graphs. We further curate $\textbf{GraphVid-Bench}$, a large-scale interaction-centric video dataset with structured relational annotations to enable training of interaction-aware video generation models. Despite using substantially less training data and fewer trainable parameters than prior motion-control methods, GraphVid delivers strong controllability and video quality. Compared with Motion-I2V, GraphVid reduces FID by up to 39.9% and FVD by 37.6%, while improving PSNR (9.87=>15.98) and SSIM (0.38=>0.61). Our results highlight the potential of structured semantic interfaces as a powerful paradigm for controllable video generation.
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Submitted 23 July, 2026;
originally announced July 2026.
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ELSA3D: Elastic Semantic Anchoring for Unified 3D Understanding and Generation
Authors:
Tianjiao Yu,
Xinzhuo Li,
Yifan Shen,
Onkar Susladkar,
Yuanzhe Liu,
Xiaona Zhou,
Ismini Lourentzou
Abstract:
Unified 3D foundation models aspire to generate 3D assets and reason about them in language within a single backbone, but their text-3D interaction remains largely implicit. Existing methods concatenate text and 3D tokens into a flat sequence and rely on self-attention, collapsing coarse structural cues and fine geometric details into one undifferentiated representation. We introduce ELSA3D, a uni…
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Unified 3D foundation models aspire to generate 3D assets and reason about them in language within a single backbone, but their text-3D interaction remains largely implicit. Existing methods concatenate text and 3D tokens into a flat sequence and rely on self-attention, collapsing coarse structural cues and fine geometric details into one undifferentiated representation. We introduce ELSA3D, a unified 3D model that addresses this with elastic semantic anchoring, structuring language and geometric reasoning jointly along matched abstraction scales. ELSA3D represents geometry with a scale-aware octree tokenizer and introduces Anchor Tokens, sparse cross-modal units that select semantic cues, route them to the most relevant 3D scale, retrieve scale-specific geometric evidence, and write the fused signal back into the unified representation, keeping interaction sparse yet precise. A lightweight per-block router makes both computation and reasoning elastic, choosing which text tokens instantiate anchors at which geometric scale so that cross-modal capacity concentrates where alignment is most needed. ELSA3D achieves state-of-the-art performance across image-to-3D generation, text-to-3D generation, and 3D captioning, outperforming the strongest unified baseline while roughly halving FLOPs and inference latency relative to the non-elastic version of the same model.
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Submitted 7 July, 2026;
originally announced July 2026.
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RewardFlow: Generate Images by Optimizing What You Reward
Authors:
Onkar Susladkar,
Dong-Hwan Jang,
Tushar Prakash,
Adheesh Juvekar,
Vedant Shah,
Ayush Barik,
Nabeel Bashir,
Muntasir Wahed,
Ritish Shrirao,
Ismini Lourentzou
Abstract:
We introduce RewardFlow, an inversion-free framework that steers pretrained diffusion and flow-matching models at inference time through multi-reward Langevin dynamics. RewardFlow unifies complementary differentiable rewards for semantic alignment, perceptual fidelity, localized grounding, object consistency, and human preference, and further introduces a differentiable VQA-based reward that provi…
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We introduce RewardFlow, an inversion-free framework that steers pretrained diffusion and flow-matching models at inference time through multi-reward Langevin dynamics. RewardFlow unifies complementary differentiable rewards for semantic alignment, perceptual fidelity, localized grounding, object consistency, and human preference, and further introduces a differentiable VQA-based reward that provides fine-grained semantic supervision through language-vision reasoning. To coordinate these heterogeneous objectives, we design a prompt-aware adaptive policy that extracts semantic primitives from the instruction, infers edit intent, and dynamically modulates reward weights and step sizes throughout sampling. Across several image editing and compositional generation benchmarks, RewardFlow delivers state-of-the-art edit fidelity and compositional alignment.
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Submitted 9 April, 2026;
originally announced April 2026.
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Best of Both Worlds: Multimodal Reasoning and Generation via Unified Discrete Flow Matching
Authors:
Onkar Susladkar,
Tushar Prakash,
Gayatri Deshmukh,
Kiet A. Nguyen,
Jiaxun Zhang,
Adheesh Juvekar,
Tianshu Bao,
Lin Chai,
Sparsh Mittal,
Inderjit S Dhillon,
Ismini Lourentzou
Abstract:
We propose UniDFlow, a unified discrete flow-matching framework for multimodal understanding, generation, and editing. It decouples understanding and generation via task-specific low-rank adapters, avoiding objective interference and representation entanglement, while a novel reference-based multimodal preference alignment optimizes relative outcomes under identical conditioning, improving faithfu…
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We propose UniDFlow, a unified discrete flow-matching framework for multimodal understanding, generation, and editing. It decouples understanding and generation via task-specific low-rank adapters, avoiding objective interference and representation entanglement, while a novel reference-based multimodal preference alignment optimizes relative outcomes under identical conditioning, improving faithfulness and controllability without large-scale retraining. UniDFlpw achieves SOTA performance across eight benchmarks and exhibits strong zero-shot generalization to tasks including inpainting, in-context image generation, reference-based editing, and compositional generation, despite no explicit task-specific training.
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Submitted 2 June, 2026; v1 submitted 12 February, 2026;
originally announced February 2026.
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Stress Tests REVEAL Fragile Temporal and Visual Grounding in Video-Language Models
Authors:
Sethuraman T V,
Savya Khosla,
Aditi Tiwari,
Vidya Ganesh,
Rakshana Jayaprakash,
Aditya Jain,
Vignesh Srinivasakumar,
Onkar Kishor Susladkar,
Srinidhi Sunkara,
Aditya Shanmugham,
Rakesh Vaideeswaran,
Abbaas Alif Mohamed Nishar,
Simon Jenni,
Derek Hoiem
Abstract:
This work investigates a fundamental question: Do Video-Language Models (VidLMs) robustly account for video content, temporal sequence, and motion? Our investigation shows that, surprisingly, they often do not. We introduce REVEAL{}, a diagnostic benchmark that probes fundamental weaknesses of contemporary VidLMs through five controlled stress tests; assessing temporal expectation bias, reliance o…
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This work investigates a fundamental question: Do Video-Language Models (VidLMs) robustly account for video content, temporal sequence, and motion? Our investigation shows that, surprisingly, they often do not. We introduce REVEAL{}, a diagnostic benchmark that probes fundamental weaknesses of contemporary VidLMs through five controlled stress tests; assessing temporal expectation bias, reliance on language-only shortcuts, video sycophancy, camera motion sensitivity, and robustness to spatiotemporal occlusion. We test leading open- and closed-source VidLMs and find that these models confidently describe reversed scenes as forward, answer questions while neglecting video content, agree with false claims, struggle with basic camera motion, and fail to aggregate temporal information amidst simple spatiotemporal masking. Humans, on the other hand, succeed at these tasks with ease. Alongside our benchmark, we provide a data pipeline that automatically generates diagnostic examples for our stress tests, enabling broader and more scalable evaluation. We will release our benchmark and code to support future research.
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Submitted 11 February, 2026;
originally announced February 2026.
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PyraTok: Language-Aligned Pyramidal Tokenizer for Video Understanding and Generation
Authors:
Onkar Susladkar,
Tushar Prakash,
Adheesh Juvekar,
Kiet A. Nguyen,
Dong-Hwan Jang,
Inderjit S Dhillon,
Ismini Lourentzou
Abstract:
Discrete video VAEs underpin modern text-to-video generation and video understanding systems, yet existing tokenizers typically learn visual codebooks at a single scale with limited vocabularies and shallow language supervision, leading to poor cross-modal alignment and zero-shot transfer. We introduce PyraTok, a language-aligned pyramidal tokenizer that learns semantically structured discrete lat…
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Discrete video VAEs underpin modern text-to-video generation and video understanding systems, yet existing tokenizers typically learn visual codebooks at a single scale with limited vocabularies and shallow language supervision, leading to poor cross-modal alignment and zero-shot transfer. We introduce PyraTok, a language-aligned pyramidal tokenizer that learns semantically structured discrete latents across multiple spatiotemporal resolutions. PyraTok builds on a pretrained video VAE and a novel Language aligned Pyramidal Quantization (LaPQ) module that discretizes encoder features at several depths using a shared large binary codebook, yielding compact yet expressive video token sequences. To tightly couple visual tokens with language, PyraTok jointly optimizes multi-scale text-guided quantization and a global autoregressive objective over the token hierarchy. Across ten benchmarks, PyraTok delivers state-of-the-art (SOTA) video reconstruction, consistently improves text-to-video quality, and sets new SOTA zero-shot performance on video segmentation, temporal action localization, and video understanding, scaling robustly to up to 4K/8K resolutions.
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Submitted 23 February, 2026; v1 submitted 22 January, 2026;
originally announced January 2026.
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Pediatric Pancreas Segmentation from MRI Scans with Deep Learning
Authors:
Elif Keles,
Merve Yazol,
Gorkem Durak,
Ziliang Hong,
Halil Ertugrul Aktas,
Zheyuan Zhang,
Linkai Peng,
Onkar Susladkar,
Necati Guzelyel,
Oznur Leman Boyunaga,
Cemal Yazici,
Mark Lowe,
Aliye Uc,
Ulas Bagci
Abstract:
Objective: Our study aimed to evaluate and validate PanSegNet, a deep learning (DL) algorithm for pediatric pancreas segmentation on MRI in children with acute pancreatitis (AP), chronic pancreatitis (CP), and healthy controls. Methods: With IRB approval, we retrospectively collected 84 MRI scans (1.5T/3T Siemens Aera/Verio) from children aged 2-19 years at Gazi University (2015-2024). The dataset…
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Objective: Our study aimed to evaluate and validate PanSegNet, a deep learning (DL) algorithm for pediatric pancreas segmentation on MRI in children with acute pancreatitis (AP), chronic pancreatitis (CP), and healthy controls. Methods: With IRB approval, we retrospectively collected 84 MRI scans (1.5T/3T Siemens Aera/Verio) from children aged 2-19 years at Gazi University (2015-2024). The dataset includes healthy children as well as patients diagnosed with AP or CP based on clinical criteria. Pediatric and general radiologists manually segmented the pancreas, then confirmed by a senior pediatric radiologist. PanSegNet-generated segmentations were assessed using Dice Similarity Coefficient (DSC) and 95th percentile Hausdorff distance (HD95). Cohen's kappa measured observer agreement. Results: Pancreas MRI T2W scans were obtained from 42 children with AP/CP (mean age: 11.73 +/- 3.9 years) and 42 healthy children (mean age: 11.19 +/- 4.88 years). PanSegNet achieved DSC scores of 88% (controls), 81% (AP), and 80% (CP), with HD95 values of 3.98 mm (controls), 9.85 mm (AP), and 15.67 mm (CP). Inter-observer kappa was 0.86 (controls), 0.82 (pancreatitis), and intra-observer agreement reached 0.88 and 0.81. Strong agreement was observed between automated and manual volumes (R^2 = 0.85 in controls, 0.77 in diseased), demonstrating clinical reliability. Conclusion: PanSegNet represents the first validated deep learning solution for pancreatic MRI segmentation, achieving expert-level performance across healthy and diseased states. This tool, algorithm, along with our annotated dataset, are freely available on GitHub and OSF, advancing accessible, radiation-free pediatric pancreatic imaging and fostering collaborative research in this underserved domain.
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Submitted 18 June, 2025;
originally announced June 2025.
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ViCTr: Vital Consistency Transfer for Pathology Aware Image Synthesis
Authors:
Onkar Susladkar,
Gayatri Deshmukh,
Yalcin Tur,
Gorkhem Durak,
Ulas Bagci
Abstract:
Synthesizing medical images remains challenging due to limited annotated pathological data, modality domain gaps, and the complexity of representing diffuse pathologies such as liver cirrhosis. Existing methods often struggle to maintain anatomical fidelity while accurately modeling pathological features, frequently relying on priors derived from natural images or inefficient multi-step sampling.…
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Synthesizing medical images remains challenging due to limited annotated pathological data, modality domain gaps, and the complexity of representing diffuse pathologies such as liver cirrhosis. Existing methods often struggle to maintain anatomical fidelity while accurately modeling pathological features, frequently relying on priors derived from natural images or inefficient multi-step sampling. In this work, we introduce ViCTr (Vital Consistency Transfer), a novel two-stage framework that combines a rectified flow trajectory with a Tweedie-corrected diffusion process to achieve high-fidelity, pathology-aware image synthesis. First, we pretrain ViCTr on the ATLAS-8k dataset using Elastic Weight Consolidation (EWC) to preserve critical anatomical structures. We then fine-tune the model adversarially with Low-Rank Adaptation (LoRA) modules for precise control over pathology severity. By reformulating Tweedie's formula within a linear trajectory framework, ViCTr supports one-step sampling, reducing inference from 50 steps to just 4, without sacrificing anatomical realism. We evaluate ViCTr on BTCV (CT), AMOS (MRI), and CirrMRI600+ (cirrhosis) datasets. Results demonstrate state-of-the-art performance, achieving a Medical Frechet Inception Distance (MFID) of 17.01 for cirrhosis synthesis 28% lower than existing approaches and improving nnUNet segmentation by +3.8% mDSC when used for data augmentation. Radiologist reviews indicate that ViCTr-generated liver cirrhosis MRIs are clinically indistinguishable from real scans. To our knowledge, ViCTr is the first method to provide fine-grained, pathology-aware MRI synthesis with graded severity control, closing a critical gap in AI-driven medical imaging research.
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Submitted 25 July, 2025; v1 submitted 8 May, 2025;
originally announced May 2025.
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Historic Scripts to Modern Vision: A Novel Dataset and A VLM Framework for Transliteration of Modi Script to Devanagari
Authors:
Harshal Kausadikar,
Tanvi Kale,
Onkar Susladkar,
Sparsh Mittal
Abstract:
In medieval India, the Marathi language was written using the Modi script. The texts written in Modi script include extensive knowledge about medieval sciences, medicines, land records and authentic evidence about Indian history. Around 40 million documents are in poor condition and have not yet been transliterated. Furthermore, only a few experts in this domain can transliterate this script into…
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In medieval India, the Marathi language was written using the Modi script. The texts written in Modi script include extensive knowledge about medieval sciences, medicines, land records and authentic evidence about Indian history. Around 40 million documents are in poor condition and have not yet been transliterated. Furthermore, only a few experts in this domain can transliterate this script into English or Devanagari. Most of the past research predominantly focuses on individual character recognition. A system that can transliterate Modi script documents to Devanagari script is needed. We propose the MoDeTrans dataset, comprising 2,043 images of Modi script documents accompanied by their corresponding textual transliterations in Devanagari. We further introduce MoScNet (\textbf{Mo}di \textbf{Sc}ript \textbf{Net}work), a novel Vision-Language Model (VLM) framework for transliterating Modi script images into Devanagari text. MoScNet leverages Knowledge Distillation, where a student model learns from a teacher model to enhance transliteration performance. The final student model of MoScNet has better performance than the teacher model while having 163$\times$ lower parameters. Our work is the first to perform direct transliteration from the handwritten Modi script to the Devanagari script. MoScNet also shows competitive results on the optical character recognition (OCR) task.
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Submitted 25 March, 2025; v1 submitted 17 March, 2025;
originally announced March 2025.
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Large Scale MRI Collection and Segmentation of Cirrhotic Liver
Authors:
Debesh Jha,
Onkar Kishor Susladkar,
Vandan Gorade,
Elif Keles,
Matthew Antalek,
Deniz Seyithanoglu,
Timurhan Cebeci,
Halil Ertugrul Aktas,
Gulbiz Dagoglu Kartal,
Sabahattin Kaymakoglu,
Sukru Mehmet Erturk,
Yuri Velichko,
Daniela Ladner,
Amir A. Borhani,
Alpay Medetalibeyoglu,
Gorkem Durak,
Ulas Bagci
Abstract:
Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive assessment, accurately segmenting cirrhotic livers presents substantial challenges due to morphological alterations and heterogeneous signal characteristics. Deep lea…
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Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive assessment, accurately segmenting cirrhotic livers presents substantial challenges due to morphological alterations and heterogeneous signal characteristics. Deep learning approaches show promise for automating these tasks, but progress has been limited by the absence of large-scale, annotated datasets. Here, we present CirrMRI600+, the first comprehensive dataset comprising 628 high-resolution abdominal MRI scans (310 T1-weighted and 318 T2-weighted sequences, totaling nearly 40,000 annotated slices) with expert-validated segmentation labels for cirrhotic livers. The dataset includes demographic information, clinical parameters, and histopathological validation where available. Additionally, we provide benchmark results from 11 state-of-the-art deep learning experiments to establish performance standards. CirrMRI600+ enables the development and validation of advanced computational methods for cirrhotic liver analysis, potentially accelerating progress toward automated Cirrhosis visual staging and personalized treatment planning.
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Submitted 7 May, 2025; v1 submitted 6 October, 2024;
originally announced October 2024.
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MotionAura: Generating High-Quality and Motion Consistent Videos using Discrete Diffusion
Authors:
Onkar Susladkar,
Jishu Sen Gupta,
Chirag Sehgal,
Sparsh Mittal,
Rekha Singhal
Abstract:
The spatio-temporal complexity of video data presents significant challenges in tasks such as compression, generation, and inpainting. We present four key contributions to address the challenges of spatiotemporal video processing. First, we introduce the 3D Mobile Inverted Vector-Quantization Variational Autoencoder (3D-MBQ-VAE), which combines Variational Autoencoders (VAEs) with masked token mod…
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The spatio-temporal complexity of video data presents significant challenges in tasks such as compression, generation, and inpainting. We present four key contributions to address the challenges of spatiotemporal video processing. First, we introduce the 3D Mobile Inverted Vector-Quantization Variational Autoencoder (3D-MBQ-VAE), which combines Variational Autoencoders (VAEs) with masked token modeling to enhance spatiotemporal video compression. The model achieves superior temporal consistency and state-of-the-art (SOTA) reconstruction quality by employing a novel training strategy with full frame masking. Second, we present MotionAura, a text-to-video generation framework that utilizes vector-quantized diffusion models to discretize the latent space and capture complex motion dynamics, producing temporally coherent videos aligned with text prompts. Third, we propose a spectral transformer-based denoising network that processes video data in the frequency domain using the Fourier Transform. This method effectively captures global context and long-range dependencies for high-quality video generation and denoising. Lastly, we introduce a downstream task of Sketch Guided Video Inpainting. This task leverages Low-Rank Adaptation (LoRA) for parameter-efficient fine-tuning. Our models achieve SOTA performance on a range of benchmarks. Our work offers robust frameworks for spatiotemporal modeling and user-driven video content manipulation. We will release the code, datasets, and models in open-source.
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Submitted 11 March, 2025; v1 submitted 10 October, 2024;
originally announced October 2024.
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Bahasa Harmony: A Comprehensive Dataset for Bahasa Text-to-Speech Synthesis with Discrete Codec Modeling of EnGen-TTS
Authors:
Onkar Kishor Susladkar,
Vishesh Tripathi,
Biddwan Ahmed
Abstract:
This research introduces a comprehensive Bahasa text-to-speech (TTS) dataset and a novel TTS model, EnGen-TTS, designed to enhance the quality and versatility of synthetic speech in the Bahasa language. The dataset, spanning \textasciitilde55.0 hours and 52K audio recordings, integrates diverse textual sources, ensuring linguistic richness. A meticulous recording setup captures the nuances of Baha…
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This research introduces a comprehensive Bahasa text-to-speech (TTS) dataset and a novel TTS model, EnGen-TTS, designed to enhance the quality and versatility of synthetic speech in the Bahasa language. The dataset, spanning \textasciitilde55.0 hours and 52K audio recordings, integrates diverse textual sources, ensuring linguistic richness. A meticulous recording setup captures the nuances of Bahasa phonetics, employing professional equipment to ensure high-fidelity audio samples. Statistical analysis reveals the dataset's scale and diversity, laying the foundation for model training and evaluation. The proposed EnGen-TTS model performs better than established baselines, achieving a Mean Opinion Score (MOS) of 4.45 $\pm$ 0.13. Additionally, our investigation on real-time factor and model size highlights EnGen-TTS as a compelling choice, with efficient performance. This research marks a significant advancement in Bahasa TTS technology, with implications for diverse language applications. Link to Generated Samples: \url{https://bahasa-harmony-comp.vercel.app/}
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Submitted 9 October, 2024;
originally announced October 2024.
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Towards Synergistic Deep Learning Models for Volumetric Cirrhotic Liver Segmentation in MRIs
Authors:
Vandan Gorade,
Onkar Susladkar,
Gorkem Durak,
Elif Keles,
Ertugrul Aktas,
Timurhan Cebeci,
Alpay Medetalibeyoglu,
Daniela Ladner,
Debesh Jha,
Ulas Bagci
Abstract:
Liver cirrhosis, a leading cause of global mortality, requires precise segmentation of ROIs for effective disease monitoring and treatment planning. Existing segmentation models often fail to capture complex feature interactions and generalize across diverse datasets. To address these limitations, we propose a novel synergistic theory that leverages complementary latent spaces for enhanced feature…
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Liver cirrhosis, a leading cause of global mortality, requires precise segmentation of ROIs for effective disease monitoring and treatment planning. Existing segmentation models often fail to capture complex feature interactions and generalize across diverse datasets. To address these limitations, we propose a novel synergistic theory that leverages complementary latent spaces for enhanced feature interaction modeling. Our proposed architecture, nnSynergyNet3D integrates continuous and discrete latent spaces for 3D volumes and features auto-configured training. This approach captures both fine-grained and coarse features, enabling effective modeling of intricate feature interactions. We empirically validated nnSynergyNet3D on a private dataset of 628 high-resolution T1 abdominal MRI scans from 339 patients. Our model outperformed the baseline nnUNet3D by approximately 2%. Additionally, zero-shot testing on healthy liver CT scans from the public LiTS dataset demonstrated superior cross-modal generalization capabilities. These results highlight the potential of synergistic latent space models to improve segmentation accuracy and robustness, thereby enhancing clinical workflows by ensuring consistency across CT and MRI modalities.
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Submitted 8 August, 2024;
originally announced August 2024.
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D2Styler: Advancing Arbitrary Style Transfer with Discrete Diffusion Methods
Authors:
Onkar Susladkar,
Gayatri Deshmukh,
Sparsh Mittal,
Parth Shastri
Abstract:
In image processing, one of the most challenging tasks is to render an image's semantic meaning using a variety of artistic approaches. Existing techniques for arbitrary style transfer (AST) frequently experience mode-collapse, over-stylization, or under-stylization due to a disparity between the style and content images. We propose a novel framework called D$^2$Styler (Discrete Diffusion Styler)…
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In image processing, one of the most challenging tasks is to render an image's semantic meaning using a variety of artistic approaches. Existing techniques for arbitrary style transfer (AST) frequently experience mode-collapse, over-stylization, or under-stylization due to a disparity between the style and content images. We propose a novel framework called D$^2$Styler (Discrete Diffusion Styler) that leverages the discrete representational capability of VQ-GANs and the advantages of discrete diffusion, including stable training and avoidance of mode collapse. Our method uses Adaptive Instance Normalization (AdaIN) features as a context guide for the reverse diffusion process. This makes it easy to move features from the style image to the content image without bias. The proposed method substantially enhances the visual quality of style-transferred images, allowing the combination of content and style in a visually appealing manner. We take style images from the WikiArt dataset and content images from the COCO dataset. Experimental results demonstrate that D$^2$Styler produces high-quality style-transferred images and outperforms twelve existing methods on nearly all the metrics. The qualitative results and ablation studies provide further insights into the efficacy of our technique. The code is available at https://github.com/Onkarsus13/D2Styler.
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Submitted 7 August, 2024;
originally announced August 2024.
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Ethical Framework for Responsible Foundational Models in Medical Imaging
Authors:
Debesh Jha,
Gorkem Durak,
Abhijit Das,
Jasmer Sanjotra,
Onkar Susladkar,
Suramyaa Sarkar,
Ashish Rauniyar,
Nikhil Kumar Tomar,
Linkai Peng,
Sirui Li,
Koushik Biswas,
Ertugrul Aktas,
Elif Keles,
Matthew Antalek,
Zheyuan Zhang,
Bin Wang,
Xin Zhu,
Hongyi Pan,
Deniz Seyithanoglu,
Alpay Medetalibeyoglu,
Vanshali Sharma,
Vedat Cicek,
Amir A. Rahsepar,
Rutger Hendrix,
A. Enis Cetin
, et al. (11 additional authors not shown)
Abstract:
The emergence of foundational models represents a paradigm shift in medical imaging, offering extraordinary capabilities in disease detection, diagnosis, and treatment planning. These large-scale artificial intelligence systems, trained on extensive multimodal and multi-center datasets, demonstrate remarkable versatility across diverse medical applications. However, their integration into clinical…
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The emergence of foundational models represents a paradigm shift in medical imaging, offering extraordinary capabilities in disease detection, diagnosis, and treatment planning. These large-scale artificial intelligence systems, trained on extensive multimodal and multi-center datasets, demonstrate remarkable versatility across diverse medical applications. However, their integration into clinical practice presents complex ethical challenges that extend beyond technical performance metrics. This study examines the critical ethical considerations at the intersection of healthcare and artificial intelligence. Patient data privacy remains a fundamental concern, particularly given these models' requirement for extensive training data and their potential to inadvertently memorize sensitive information. Algorithmic bias poses a significant challenge in healthcare, as historical disparities in medical data collection may perpetuate or exacerbate existing healthcare inequities across demographic groups. The complexity of foundational models presents significant challenges regarding transparency and explainability in medical decision-making. We propose a comprehensive ethical framework that addresses these challenges while promoting responsible innovation. This framework emphasizes robust privacy safeguards, systematic bias detection and mitigation strategies, and mechanisms for maintaining meaningful human oversight. By establishing clear guidelines for development and deployment, we aim to harness the transformative potential of foundational models while preserving the fundamental principles of medical ethics and patient-centered care.
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Submitted 7 August, 2026; v1 submitted 13 April, 2024;
originally announced June 2024.
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Large-Scale Multi-Center CT and MRI Segmentation of Pancreas with Deep Learning
Authors:
Zheyuan Zhang,
Elif Keles,
Gorkem Durak,
Yavuz Taktak,
Onkar Susladkar,
Vandan Gorade,
Debesh Jha,
Asli C. Ormeci,
Alpay Medetalibeyoglu,
Lanhong Yao,
Bin Wang,
Ilkin Sevgi Isler,
Linkai Peng,
Hongyi Pan,
Camila Lopes Vendrami,
Amir Bourhani,
Yury Velichko,
Boqing Gong,
Concetto Spampinato,
Ayis Pyrros,
Pallavi Tiwari,
Derk C. F. Klatte,
Megan Engels,
Sanne Hoogenboom,
Candice W. Bolan
, et al. (13 additional authors not shown)
Abstract:
Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are understudied, largely due to a lack of publicly available datasets, benchmarking research efforts, and domain-specific deep learning methods. In this retrospective st…
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Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are understudied, largely due to a lack of publicly available datasets, benchmarking research efforts, and domain-specific deep learning methods. In this retrospective study, we collected a large dataset (767 scans from 499 participants) of T1-weighted (T1W) and T2-weighted (T2W) abdominal MRI series from five centers between March 2004 and November 2022. We also collected CT scans of 1,350 patients from publicly available sources for benchmarking purposes. We developed a new pancreas segmentation method, called PanSegNet, combining the strengths of nnUNet and a Transformer network with a new linear attention module enabling volumetric computation. We tested PanSegNet's accuracy in cross-modality (a total of 2,117 scans) and cross-center settings with Dice and Hausdorff distance (HD95) evaluation metrics. We used Cohen's kappa statistics for intra and inter-rater agreement evaluation and paired t-tests for volume and Dice comparisons, respectively. For segmentation accuracy, we achieved Dice coefficients of 88.3% (std: 7.2%, at case level) with CT, 85.0% (std: 7.9%) with T1W MRI, and 86.3% (std: 6.4%) with T2W MRI. There was a high correlation for pancreas volume prediction with R^2 of 0.91, 0.84, and 0.85 for CT, T1W, and T2W, respectively. We found moderate inter-observer (0.624 and 0.638 for T1W and T2W MRI, respectively) and high intra-observer agreement scores. All MRI data is made available at https://osf.io/kysnj/. Our source code is available at https://github.com/NUBagciLab/PaNSegNet.
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Submitted 24 October, 2024; v1 submitted 20 May, 2024;
originally announced May 2024.
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MOVES: Movable and Moving LiDAR Scene Segmentation in Label-Free settings using Static Reconstruction
Authors:
Prashant Kumar,
Dhruv Makwana,
Onkar Susladkar,
Anurag Mittal,
Prem Kumar Kalra
Abstract:
Accurate static structure reconstruction and segmentation of non-stationary objects is of vital importance for autonomous navigation applications. These applications assume a LiDAR scan to consist of only static structures. In the real world however, LiDAR scans consist of non-stationary dynamic structures - moving and movable objects. Current solutions use segmentation information to isolate and…
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Accurate static structure reconstruction and segmentation of non-stationary objects is of vital importance for autonomous navigation applications. These applications assume a LiDAR scan to consist of only static structures. In the real world however, LiDAR scans consist of non-stationary dynamic structures - moving and movable objects. Current solutions use segmentation information to isolate and remove moving structures from LiDAR scan. This strategy fails in several important use-cases where segmentation information is not available. In such scenarios, moving objects and objects with high uncertainty in their motion i.e. movable objects, may escape detection. This violates the above assumption. We present MOVES, a novel GAN based adversarial model that segments out moving as well as movable objects in the absence of segmentation information. We achieve this by accurately transforming a dynamic LiDAR scan to its corresponding static scan. This is obtained by replacing dynamic objects and corresponding occlusions with static structures which were occluded by dynamic objects. We leverage corresponding static-dynamic LiDAR pairs.
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Submitted 15 October, 2023; v1 submitted 26 June, 2023;
originally announced June 2023.
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TPFNet: A Novel Text In-painting Transformer for Text Removal
Authors:
Onkar Susladkar,
Dhruv Makwana,
Gayatri Deshmukh,
Sparsh Mittal,
Sai Chandra Teja R,
Rekha Singhal
Abstract:
Text erasure from an image is helpful for various tasks such as image editing and privacy preservation. In this paper, we present TPFNet, a novel one-stage (end-toend) network for text removal from images. Our network has two parts: feature synthesis and image generation. Since noise can be more effectively removed from low-resolution images, part 1 operates on low-resolution images. The output of…
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Text erasure from an image is helpful for various tasks such as image editing and privacy preservation. In this paper, we present TPFNet, a novel one-stage (end-toend) network for text removal from images. Our network has two parts: feature synthesis and image generation. Since noise can be more effectively removed from low-resolution images, part 1 operates on low-resolution images. The output of part 1 is a low-resolution text-free image. Part 2 uses the features learned in part 1 to predict a high-resolution text-free image. In part 1, we use "pyramidal vision transformer" (PVT) as the encoder. Further, we use a novel multi-headed decoder that generates a high-pass filtered image and a segmentation map, in addition to a text-free image. The segmentation branch helps locate the text precisely, and the high-pass branch helps in learning the image structure. To precisely locate the text, TPFNet employs an adversarial loss that is conditional on the segmentation map rather than the input image. On Oxford, SCUT, and SCUT-EnsText datasets, our network outperforms recently proposed networks on nearly all the metrics. For example, on SCUT-EnsText dataset, TPFNet has a PSNR (higher is better) of 39.0 and text-detection precision (lower is better) of 21.1, compared to the best previous technique, which has a PSNR of 32.3 and precision of 53.2. The source code can be obtained from https://github.com/CandleLabAI/TPFNet
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Submitted 27 October, 2022; v1 submitted 26 October, 2022;
originally announced October 2022.
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ACLNet: An Attention and Clustering-based Cloud Segmentation Network
Authors:
Dhruv Makwana,
Subhrajit Nag,
Onkar Susladkar,
Gayatri Deshmukh,
Sai Chandra Teja R,
Sparsh Mittal,
C Krishna Mohan
Abstract:
We propose a novel deep learning model named ACLNet, for cloud segmentation from ground images. ACLNet uses both deep neural network and machine learning (ML) algorithm to extract complementary features. Specifically, it uses EfficientNet-B0 as the backbone, "`a trous spatial pyramid pooling" (ASPP) to learn at multiple receptive fields, and "global attention module" (GAM) to extract finegrained d…
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We propose a novel deep learning model named ACLNet, for cloud segmentation from ground images. ACLNet uses both deep neural network and machine learning (ML) algorithm to extract complementary features. Specifically, it uses EfficientNet-B0 as the backbone, "`a trous spatial pyramid pooling" (ASPP) to learn at multiple receptive fields, and "global attention module" (GAM) to extract finegrained details from the image. ACLNet also uses k-means clustering to extract cloud boundaries more precisely. ACLNet is effective for both daytime and nighttime images. It provides lower error rate, higher recall and higher F1-score than state-of-art cloud segmentation models. The source-code of ACLNet is available here: https://github.com/ckmvigil/ACLNet.
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Submitted 13 July, 2022;
originally announced July 2022.