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Pattern Formation in Bioconvection of Thiovulum in a Hele-Shaw Chamber
Authors:
Trey Johnson,
George A. Schaible,
Yujia Qi,
Fridtjof Brauns,
Alexander Cohen,
Jean-Marie Volland,
Ousmane Kodio
Abstract:
This paper is associated with a video winner of a 2025 American Physical Society's Division of Fluid Dynamics (DFD) Gallery of Fluid Motion Award for work presented at the DFD Gallery of Fluid Motion. The original video is available online at the Gallery of Fluid Motion, https://doi.org/10.1103/APS.DFD.2025.GFM.V045.
We investigate bioconvection in a colony of Thiovulum sp. ST bacteria, a recent…
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This paper is associated with a video winner of a 2025 American Physical Society's Division of Fluid Dynamics (DFD) Gallery of Fluid Motion Award for work presented at the DFD Gallery of Fluid Motion. The original video is available online at the Gallery of Fluid Motion, https://doi.org/10.1103/APS.DFD.2025.GFM.V045.
We investigate bioconvection in a colony of Thiovulum sp. ST bacteria, a recently isolated enrichment culture, confined within a Hele-Shaw chamber. Driven by chemotactic and gravitactic responses, the cells collectively develop striking emergent patterns and convection-like dynamics. Starting from a dense, homogeneous suspension, the swimming bacteria generate large-scale bioconvective flows within minutes. Although these flows resemble thermal convection, they arise in the absence of an imposed temperature gradient. Instead, they arise from the collective swimming of bacteria responding to oxygen gradients and gravity.
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Submitted 17 August, 2026;
originally announced August 2026.
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Focal-point scanning for dose delivery and optimization with focused laser-accelerated very-high-energy electron beams
Authors:
Zhiyuan Guo,
Yifei Pi,
Junwei Zhou,
Guoqing Liu,
Wenbo Zhang,
Haiyang Wang,
Yaping Qi,
Xiaoming Guo,
Yuhan Zhang,
Bo Peng,
Jianfei Hua,
Yang Wan,
Wei Lu
Abstract:
Focused very-high-energy electron (VHEE) beams can produce localized dose enhancement at selected depths, but irradiation of a finite target requires coordinated control of multiple focal positions, incidence directions, and beam weights while limiting exposure of nearby organs at risk (OARs). We present Focal-Point Scanning (FPS), a dose delivery and optimization method developed for laser wakefi…
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Focused very-high-energy electron (VHEE) beams can produce localized dose enhancement at selected depths, but irradiation of a finite target requires coordinated control of multiple focal positions, incidence directions, and beam weights while limiting exposure of nearby organs at risk (OARs). We present Focal-Point Scanning (FPS), a dose delivery and optimization method developed for laser wakefield accelerator (LWFA)-driven VHEE beams. The method is based on a two-dipole focusing system that produces single-plane beam convergence and allows the focal position to be varied by changing the magnetic field strength. FPS distributes focal points throughout the planning target volume and determines focal-point-specific incidence sectors according to the geometry of nearby critical OARs. The method was evaluated using the AAPM TG119 C-shape benchmark and one previously treated lung radiotherapy case. At matched target coverage, FPS reduced the TG119 Core mean dose by approximately one half relative to parallel VHEE and intensity-modulated x-ray plans, approaching the single-field proton pencil-beam-scanning reference. In the lung case, FPS maintained target coverage comparable to the clinical volumetric modulated arc therapy reference while reducing the mean dose to every evaluated OAR; spinal-cord mean and maximum doses decreased by 93.2% and 87.2%, respectively. The evaluated OAR mean doses varied little across rms energy spreads of 0 to 10% and for a flat-top electron spectrum spanning 150 to 250 MeV. These results demonstrate that focal-point-specific angular selection can translate focused-beam physics into effective OAR sparing and support FPS as a planning strategy for broadband LWFA-VHEE radiotherapy.
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Submitted 13 August, 2026;
originally announced August 2026.
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Fast and wide-range wavelength tuning of a III-V/Si3N4 external-cavity laser via two-step pulsed heating
Authors:
Cong Wang,
Fuyi Cao,
Xin Xu,
Yihan Qi,
Dongxin Jiang,
Masataka Kobayashi,
To-Fan Pan,
Zhan Su,
Guoen Weng,
Hidefumi Akiyama,
Shaoqiang Chen
Abstract:
Fast and wide-range wavelength switching is desirable for optical communications and photonic systems that are frequency-agile. However, thermo-optic (TO)-tuned integrated lasers often have limited switching times and tuning rates. This study demonstrates a hybrid-integrated III-V/Si3N4 external-cavity laser (ECL), combining a dual-microring Vernier filter with thermal pumping to give wide-range a…
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Fast and wide-range wavelength switching is desirable for optical communications and photonic systems that are frequency-agile. However, thermo-optic (TO)-tuned integrated lasers often have limited switching times and tuning rates. This study demonstrates a hybrid-integrated III-V/Si3N4 external-cavity laser (ECL), combining a dual-microring Vernier filter with thermal pumping to give wide-range and fast wavelength control. The ECL provides single-mode static lasing wavelength tuning in the 1486-1614 nm range. Impulsive thermal pumping that is applied through microheaters with shorter duration and higher amplitude accelerates the switching time. A simple first-order thermal fit reproduces the measurements well, indicating that the TO-tuning dynamics are highly predictable. Consequently, two-step pulse thermal pumping is applied to the on-chip microheaters to exploit the initial quasi-linear heating transient and sustain the target wavelength at a subsequent equilibrium. The results show that 101 and 104 nm red- and blue-shift switches are achieved with quasi-linear tuning rates of 8.91 and 9.68 nm/us, respectively. This approach provides a practical route toward fast wavelength switching in TO-tuned ECLs, potentially extending their applicability within frequency-agile systems, such as wavelength-division multiplexed transceivers.
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Submitted 13 August, 2026;
originally announced August 2026.
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Breaking the trade-off between invisibility and sensitivity in electromagnetic sensing
Authors:
Yichao Liu,
Jiaxue Zhou,
Weifeng Han,
Hanchuan Chen,
Fei Sun,
Qin Liao,
Hengxiang Zhang,
Xiaofan Ji,
Yawen Qi
Abstract:
Weak electromagnetic signals demand highly sensitive sensors, yet increasing a sensor's sensitivity inevitably strengthens its interaction with the surrounding field, producing scattering that perturbs the very signals being measured. Conversely, existing cloaking strategies suppress scattering only by isolating the sensor from incident waves, thereby compromising signal reception. Resolving this…
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Weak electromagnetic signals demand highly sensitive sensors, yet increasing a sensor's sensitivity inevitably strengthens its interaction with the surrounding field, producing scattering that perturbs the very signals being measured. Conversely, existing cloaking strategies suppress scattering only by isolating the sensor from incident waves, thereby compromising signal reception. Resolving this long-standing trade-off between invisibility and sensitivity has remained an outstanding challenge. Here we overcome this dilemma through an integrated transformation-optical architecture that co-designs the entire sensing system, including the electrically large sensor body, the subwavelength sensing probe, and their electrical interconnection. The proposed multifunctional core-shell structure guides incident waves around the sensor body while simultaneously concentrating them into the sensing region without disturbing the external electromagnetic field. A deep-subwavelength aperture preserves electrical connectivity without degrading either cloaking or field concentration, enabling invisible sensing within a single platform. A microwave prototype based on practical optic-null-medium metamaterials experimentally demonstrates broadband scattering suppression exceeding 3 dB together with an average sixfold enhancement of the detected signal over 4.9-5.1 GHz. By simultaneously eliminating measurement-induced field perturbation and amplifying the local sensing field, our approach establishes a general framework for invisible yet highly responsive electromagnetic sensors, opening new opportunities for weak-signal detection in biomedical diagnostics, secure communications, quantum technologies, and deep-space exploration.
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Submitted 3 August, 2026;
originally announced August 2026.
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Parenclitic hypergraphs and their application in personalized cancer therapy
Authors:
K. K. H. Manjunatha,
D. Aleja,
F. Liu,
M. Zhang,
Y. Qi,
L. Minati,
G. -Q. Sun,
S. Zhuang,
C. Cai,
J. Li,
R. Criado,
M. Romance del Rio,
D. Papo,
Y. -J. Ma,
F. Fang,
C. I. del Genio,
Z. Zhao,
H. Gao,
S. Boccaletti
Abstract:
Understanding the differences between individual instances of the same complex system remains a central challenge, particularly in biological contexts. Parenclitic networks constitute a suitable means to detect deviations in correlations with respect to reference populations. Here, we introduce parenclitic hypergraphs, a general framework for identifying anomalies in higher-order correlations acro…
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Understanding the differences between individual instances of the same complex system remains a central challenge, particularly in biological contexts. Parenclitic networks constitute a suitable means to detect deviations in correlations with respect to reference populations. Here, we introduce parenclitic hypergraphs, a general framework for identifying anomalies in higher-order correlations across arbitrary interaction orders. After validating the method on synthetic datasets and benchmark ones, we apply it to patient-derived cancer organoids, capturing temporal changes in gene expression between healthy and cancerous tissues as the disease progresses. Our approach not only reproduces known oncogenic signatures, but also reveals a previously unrecognized candidate therapeutic target. Since organoids are generated from individual patients, our method provides, for the first time, a viable protocol for personalized cancer therapy based on higher-order correlation patterns. These findings offer a novel, systems-level strategy for precision oncology grounded in complex systems theory.
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Submitted 6 July, 2026;
originally announced July 2026.
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Observation of fractality-induced topology in photonic crystals
Authors:
Bei Yan,
Yingfeng Qi,
Xiang Xi,
Linyun Yang,
Yan Meng,
Zhen-Xiao Zhu,
Jing-Ming Chen,
Ziyao Wang,
Zhen Gao
Abstract:
Fractal topology--achieved by integrating nontrivial topology into fractal geometries with self-similarity and non-integer dimensions--has opened new avenues for exploring topological phases of matter. Recent theoretical advances revealed a counterintuitive fractal topology: fractality itself can induce nontrivial topology in an otherwise trivial system. Here, we report the first experimental obse…
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Fractal topology--achieved by integrating nontrivial topology into fractal geometries with self-similarity and non-integer dimensions--has opened new avenues for exploring topological phases of matter. Recent theoretical advances revealed a counterintuitive fractal topology: fractality itself can induce nontrivial topology in an otherwise trivial system. Here, we report the first experimental observation of fractality-induced topology in a tight-binding-like photonic crystal, without relying on traditional driving mechanisms such as magnetic fields, staggered hopping, or spin-orbit coupling. We demonstrate that fractality alone is sufficient to lift the degeneracy of Kagome lattice band structure and induce topological corner states within the bandgap of the resulting fractal Kagome photonic crystal, which is a photonic higher-order topological insulator. This work experimentally reveals a novel mechanism for realizing nontrivial topological states, expanding both the fundamental frontier and potential application of topological physics.
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Submitted 23 June, 2026;
originally announced June 2026.
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Full-field prediction for engineering-scale three-dimensional aircraft with multigrid-hierarchical learning
Authors:
Yunfei Liu,
Hao Wang,
Yuhang Qi,
Hao Yue,
Dehong Meng,
Wei Li,
Rui Wang,
Tiejun Li,
Jie Liu,
Junwu Hong,
Xinhai Chen
Abstract:
High-fidelity computational fluid dynamics is essential for aerospace design, but engineering-scale simulations of practical three-dimensional aircraft remain computationally expensive. Learning-based flow-field initialization can improve efficiency by reducing the numerical distance between the initial and converged solutions, yet existing deep learning approaches remain difficult to scale to lar…
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High-fidelity computational fluid dynamics is essential for aerospace design, but engineering-scale simulations of practical three-dimensional aircraft remain computationally expensive. Learning-based flow-field initialization can improve efficiency by reducing the numerical distance between the initial and converged solutions, yet existing deep learning approaches remain difficult to scale to large three-dimensional aircraft flows with multiscale regional heterogeneity. Most prior studies therefore focus on two-dimensional problems, surface quantities, integral aerodynamic coefficients, or simplified three-dimensional cases with limited grid resolution.Here we propose MHLF, a multigrid-hierarchical learning framework for accelerating engineering-scale aircraft flow simulations while preserving high-fidelity numerical accuracy. MHLF combines a topologically consistent geometric multigrid representation with a hierarchical strategy that captures regional flow heterogeneity during both prediction and subsequent CFD correction. Across three engineering-scale aircraft cases spanning Mach 0.15 to 6.0 and covering subsonic, transonic and supersonic regimes, MHLF accelerates convergence without sacrificing flow-field accuracy, achieving a 3 to 8 times efficiency improvement over conventional initialization. These results demonstrate practical full-flow-field prediction for large three-dimensional aircraft within the CFD domain and provide a foundation for data-driven acceleration of high-fidelity aircraft flow simulation.
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Submitted 26 May, 2026;
originally announced May 2026.
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Decoupling heat and electricity: A thermal invisible gateway
Authors:
Jiahao Li,
Fei Sun,
Yichao Liu,
Yawen Qi,
Qin Liao,
Jianpu Yang,
Zhiru Xie
Abstract:
The Wiedemann-Franz law couples electrical and thermal conductivity, making high electrical conduction with low thermal conduction a major challenge. To overcome this, we designed an active thermal metasurface (ATMS) - based thermal invisible gateway that decouples thermal and electrical paths. Built on a copper substrate with a dumbbell-shaped bridge, the structure suppresses heat flow via direct…
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The Wiedemann-Franz law couples electrical and thermal conductivity, making high electrical conduction with low thermal conduction a major challenge. To overcome this, we designed an active thermal metasurface (ATMS) - based thermal invisible gateway that decouples thermal and electrical paths. Built on a copper substrate with a dumbbell-shaped bridge, the structure suppresses heat flow via directional compensation while allowing unimpeded electrical conduction. Room-temperature experiments show an effective thermal conductivity below 10^-3 W m^-1 K^-1 (near zero, air-like insulation) and an electrical conductivity up to 2.8x10^7 S m^-1 (metal-level). Unlike conventional material-modification approaches, our work uses macroscopic structural design to break the intrinsic coupling, offering a promising solution for applications like on-chip interconnects and wearable electronics.
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Submitted 28 May, 2026; v1 submitted 28 May, 2026;
originally announced May 2026.
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Crosstalk-free Chiral Anomaly Bulk States in Photonic Crystals
Authors:
Guochao Wei,
Yingfeng Qi,
Kang Du,
Wei Zhu,
Zhenzhen Liu,
Junjun Xiao,
Shengxiang Wang,
Zhen Gao
Abstract:
Ultracompact cladding-free waveguide arrays with zero inter-channel spacing and negligible crosstalk open a new avenue for high-density integrated photonic circuits. However, existing cladding-free waveguide arrays typically rely on conventional trivial bulk modes, making them highly susceptible to scattering losses at sharp bends or in the presence of obstacles and defects. To overcome this limit…
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Ultracompact cladding-free waveguide arrays with zero inter-channel spacing and negligible crosstalk open a new avenue for high-density integrated photonic circuits. However, existing cladding-free waveguide arrays typically rely on conventional trivial bulk modes, making them highly susceptible to scattering losses at sharp bends or in the presence of obstacles and defects. To overcome this limitation, we theoretically propose and experimentally demonstrate a robust, crosstalk-free, and cladding-free photonic waveguide array based on chiral anomaly bulk states (CABSs) in photonic crystals. By interfacing distinct Dirac photonic crystals that host Dirac cones at different high-symmetry points (Γ and K) in the Brillouin zone and carefully engineering the boundary conditions, the boundary-induced CABSs in adjacent channels become effectively decoupled due to a large momentum separation, thereby eliminating inter-channel crosstalk. More importantly, we experimentally demonstrate that these crosstalk-free CABSs are robust to perturbations, including metallic obstacles, air defects, and sharp bends. We further extend the CABS-based waveguide array to two dimensions and demonstrate a cladding-free triangular resonator and a crosstalk-free waveguide crossing, both of which are previously unattainable. Our work establishes a new design paradigm for cladding-free, crosstalk-free, and ultracompact topological photonic devices, paving the way for robust, highly integrated photonic circuits.
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Submitted 17 May, 2026;
originally announced May 2026.
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Clock-state olfactory search in turbulent flows using Q-learning: The geometry of plume recovery
Authors:
Marco Rando,
Robin A. Heinonen,
Yujia Qi,
Agnese Seminara
Abstract:
Finding an odor source in a turbulent flow requires effectively leveraging the history of olfactory observations into a robust navigation strategy. In this work, we use tabular Q-learning to train an olfactory search agent with a minimal memory of past observations: only a running clock since the last whiff. This agent learns an interpretable strategy to recover the plume which combines well-known…
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Finding an odor source in a turbulent flow requires effectively leveraging the history of olfactory observations into a robust navigation strategy. In this work, we use tabular Q-learning to train an olfactory search agent with a minimal memory of past observations: only a running clock since the last whiff. This agent learns an interpretable strategy to recover the plume which combines well-known behaviors observed in insects: surging, casting, and a return downwind. While achieving good performance on data from direct numerical simulations of turbulence, the agent is limited by an inability to adapt its strategy to the local intermittency level; we show that providing more flexibility improves robustness.
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Submitted 15 May, 2026;
originally announced May 2026.
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Preparation of quasi-two-dimensional Bose mixture of ultracold $^{23}$Na and $^{87}$Rb atoms
Authors:
Ji-Kai Liao,
Hao-Ran Zhang,
Xiao-Rong Yu,
Ya-Qun Qi,
Yi-Cheng Guo,
Bo Zhao,
Jun Rui,
Jian-Wei Pan
Abstract:
Quantum gases confined in reduced dimensions have enabled the observation of many exotic quantum phenomena. While existing experiments primarily focus on homonuclear systems, we report here on the efficient preparation of a quasi-two-dimensional (2D) heteronuclear quantum degenerate mixture of ultracold $^{23}$Na and $^{87}$Rb. We describe the design of the vacuum system and detail the experimenta…
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Quantum gases confined in reduced dimensions have enabled the observation of many exotic quantum phenomena. While existing experiments primarily focus on homonuclear systems, we report here on the efficient preparation of a quasi-two-dimensional (2D) heteronuclear quantum degenerate mixture of ultracold $^{23}$Na and $^{87}$Rb. We describe the design of the vacuum system and detail the experimental procedures for preparing the 2D quantum mixture. The designed apparatus has several unique features, including compact and modular 2D-MOT sources, a science chamber that accommodates various lattice geometries, a precision in-vacuum electrode assembly, and high-resolution imaging for both atomic species. After loading the dual-species condensate into a single layer of a vertical optical lattice, we prepare a 2D gas mixture and observe quantum immiscibility in the in-situ equilibrium density profiles. The observed density profiles agree well with mean-field theories. The apparatus provides a versatile platform for investigating several interesting problems, including quantum impurities, quantum droplets, or polar molecules in low dimensions.
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Submitted 9 July, 2026; v1 submitted 20 April, 2026;
originally announced April 2026.
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Hierarchical Iterative Method in CFD Numerical Solution
Authors:
Dehong Meng,
Hao Yue,
Hao Wang,
Wei Li,
Yuhang Qi,
Rui Wang,
Junwu Hong
Abstract:
We propose a hierarchical asynchronous iterative method that differs from the traditional synchronous iterative method used across the entire flow field in conventional Computational Fluid Dynamics applications. This method forcibly divides the spatial region of the flow field into three layers: the boundary layer, the inner field, and the outer field. By adopting a novel approach of using differe…
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We propose a hierarchical asynchronous iterative method that differs from the traditional synchronous iterative method used across the entire flow field in conventional Computational Fluid Dynamics applications. This method forcibly divides the spatial region of the flow field into three layers: the boundary layer, the inner field, and the outer field. By adopting a novel approach of using different iteration steps for each layer, it significantly enhances computational efficiency. Using the hierarchical iterative method, numerical simulation studies were conducted on three typical benchmark models with different velocity ranges. Additionally, discussions were held regarding new modes such as using different control equations and computational parameters for each layer. The results based on structured grids indicate that, for the cases studied in this paper, the proposed method can achieve identical simulation results compared to traditional methods while only consuming 53.2% of the computational time of traditional methods, without significantly increasing manpower costs. This paper provides suggestions and discusses on the numerical applications of this novel iterative mode, and offers new insights for follow-up research based on this method.
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Submitted 24 May, 2026; v1 submitted 10 April, 2026;
originally announced April 2026.
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Statistics of blob properties in two types of coronal streamers
Authors:
Haiyi Li,
Zhenghua Huang,
Maria S. Madjarska,
Youqian Qi,
Hui Fu,
Ming Xiong,
Lidong Xia
Abstract:
Previous studies have shown that a streamer blob might originate in the lower corona and thus be affected by activity in that region. While the base of one streamer might differ from that of another, it can be cataloged into two distinct types: active region streamers (ARSs) that have active regions at their base, and quiet equatorial streamers (QESs) that do not have an active region underneath.T…
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Previous studies have shown that a streamer blob might originate in the lower corona and thus be affected by activity in that region. While the base of one streamer might differ from that of another, it can be cataloged into two distinct types: active region streamers (ARSs) that have active regions at their base, and quiet equatorial streamers (QESs) that do not have an active region underneath.The difference between the blob properties in ARSs and those in QESs remains unknown. By analyzing the whole-year observations from SOHO/LASCO/C2 in 2018, we carried out a statistical analysis of the properties of propagating blobs in ARSs and QESs. We found that the properties of streamer blobs are very different from one blob to another. The occurrence rate of blobs in ARSs is about twice as high as that in QESs. On average, the ARS blobs have significantly higher initial velocities and slightly higher accelerations, but slightly lower heights of first appearance than the QES blobs. There is a weak positive correlation between the initial velocities and heights of first appearance in the two groups of streamer blobs. The correlation between the accelerations and heights of first appearance in ARS blobs is negative, while that in QES blobs is positive. Our results provide statistical evidence that a higher degree of activity at the coronal base of a streamer can cause more dynamic blobs higher up, and that it affects the structures of the solar wind originating in the region.
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Submitted 6 April, 2026;
originally announced April 2026.
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Few-picosecond pulse generation featuring ultrafast spectral dynamics in gain-switched surface-grating DFB lasers via impulsive optical pumping
Authors:
Yihan Qi,
Fuyi Cao,
Hidekazu Nakamae,
Changsu Kim,
Masataka Kobayashi,
Cong Wang,
To-Fan Pan,
Shaoqiang Chen,
Takashi Ito,
Hidefumi Akiyama
Abstract:
To investigate the physics of picosecond gain-switching dynamics in single-mode lasers under femtosecond optical pumping at room temperature, we designed and fabricated first-order surface-grating GaAs distributed-feedback (DFB) lasers with five systematically varied grating periods (120-124 nm), corresponding to lasing wavelengths of 825.7-849.5 nm (1.502-1.459 eV). The 124-nm-period device, clos…
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To investigate the physics of picosecond gain-switching dynamics in single-mode lasers under femtosecond optical pumping at room temperature, we designed and fabricated first-order surface-grating GaAs distributed-feedback (DFB) lasers with five systematically varied grating periods (120-124 nm), corresponding to lasing wavelengths of 825.7-849.5 nm (1.502-1.459 eV). The 124-nm-period device, closest to the quantum-well gain peak among the investigated devices, exhibited the highest output power and spectral bandwidth. Among all devices, the 122-nm-period DFB laser (838.2 nm, 1.480 eV) generated the shortest pulses, despite lasing at a higher photon energy and lower output power than the device closest to the gain peak. All devices exhibited characteristic down-chirp behavior that increased with excitation power. The shortest pulses had a chirped pulse width of 6.6 ps and a chirp rate of 0.13 meV/ps, whereas spectrally resolved measurements revealed a minimum pulse width of 3.8 ps (2.3 ps after deconvolution of the detection time resolution) near the central photon energy of the pulse spectrum. Numerical simulations revealed temporally and spatially resolved dynamics of photons, carriers, gain, and refractive index, reproducing the experimental results qualitatively and quantitatively. Furthermore, a mechanism for generating the shortest pulses at photon energies above the gain peak was identified and attributed to higher differential gain, saturation gain, and a higher transparency carrier density in the high-energy region of the gain spectrum. These experimental and theoretical results elucidate the intrinsic dynamics of picosecond pulse generation in gain-switched DFB lasers and provide design guidance for short-pulse generation and computational tools applicable to both optical and electrical pumping.
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Submitted 2 April, 2026;
originally announced April 2026.
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Project and Generate: Divergence-Free Neural Operators for Incompressible Flows
Authors:
Xigui Li,
Hongwei Zhang,
Ruoxi Jiang,
Deshu Chen,
Chensen Lin,
Limei Han,
Yuan Qi,
Xin Guo,
Yuan Cheng
Abstract:
Learning-based models for fluid dynamics often operate in unconstrained function spaces, leading to physically inadmissible, unstable simulations. While penalty-based methods offer soft regularization, they provide no structural guarantees, resulting in spurious divergence and long-term collapse. In this work, we introduce a unified framework that enforces the incompressible continuity equation as…
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Learning-based models for fluid dynamics often operate in unconstrained function spaces, leading to physically inadmissible, unstable simulations. While penalty-based methods offer soft regularization, they provide no structural guarantees, resulting in spurious divergence and long-term collapse. In this work, we introduce a unified framework that enforces the incompressible continuity equation as a hard, intrinsic constraint for both deterministic and generative modeling. First, to project deterministic models onto the divergence-free subspace, we integrate a differentiable spectral Leray projection grounded in the Helmholtz-Hodge decomposition, which restricts the regression hypothesis space to physically admissible velocity fields. Second, to generate physically consistent distributions, we show that simply projecting model outputs is insufficient when the prior is incompatible. To address this, we construct a divergence-free Gaussian reference measure via a curl-based pushforward, ensuring the entire probability flow remains subspace-consistent by construction. Experiments on 2D Navier-Stokes equations demonstrate exact incompressibility up to discretization error and substantially improved stability and physical consistency.
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Submitted 25 March, 2026;
originally announced March 2026.
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Suiren-1.0 Technical Report: A Family of Molecular Foundation Models
Authors:
Junyi An,
Xinyu Lu,
Yun-Fei Shi,
Li-Cheng Xu,
Nannan Zhang,
Chao Qu,
Yuan Qi,
Fenglei Cao
Abstract:
We introduce Suiren-1.0, a family of molecular foundation models for the accurate modeling of diverse organic systems. Suiren-1.0 comprising three specialized variants (Suiren-Base, Suiren-Dimer, and Suiren-ConfAvg) is integrated within an algorithmic framework that bridges the gap between 3D conformational geometry and 2D statistical ensemble spaces. We first pre-train Suiren-Base (1.8B parameter…
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We introduce Suiren-1.0, a family of molecular foundation models for the accurate modeling of diverse organic systems. Suiren-1.0 comprising three specialized variants (Suiren-Base, Suiren-Dimer, and Suiren-ConfAvg) is integrated within an algorithmic framework that bridges the gap between 3D conformational geometry and 2D statistical ensemble spaces. We first pre-train Suiren-Base (1.8B parameters) on a 70M-sample Density Functional Theory dataset using spatial self-supervision and SE(3)-equivariant architectures, achieving robust performance in quantum property prediction. Suiren-Dimer extends this capability through continued pre-training on 13.5M intermolecular interaction samples. To enable efficient downstream application, we propose Conformation Compression Distillation (CCD), a diffusion-based framework that distills complex 3D structural representations into 2D conformation-averaged representations. This yields the lightweight Suiren-ConfAvg, which generates high-fidelity representations from SMILES or molecular graphs. Our extensive evaluations demonstrate that Suiren-1.0 establishes state-of-the-art results across a range of tasks. All models and benchmarks are open-sourced.
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Submitted 28 April, 2026; v1 submitted 23 March, 2026;
originally announced March 2026.
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Low Energy Phonon Bursts Created By Fast Neutron Damage
Authors:
A. Armatol,
C. Augier,
L. Bergé,
J. Billard,
H. J. Birch,
J. Blé,
C. L. Chang,
Y. -Y. Chang,
L. Chaplinsky,
G. Cline,
A. Cochard,
I. Cojocari,
J. Colas,
M. De Jesus,
P. de Marcillac,
K. Dwinger,
R. Faure,
S. Fiorucci,
M. Garcia-Sciveres,
J. Gascon,
C. Girard-Carillo,
W. Guo,
L. Haegel,
S. J. Haselschwardt,
S. A. Hertel
, et al. (45 additional authors not shown)
Abstract:
Solid state athermal phonon calorimeters used in the search for low mass dark matter or coherent neutrino-nucleus interactions have long observed a large excess of events below several hundred eV. The relaxation of damage created by the interaction of fast cosmic ray neutrons with the detector has been proposed as a source of these excess events. By comparing neutron exposed detectors to control d…
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Solid state athermal phonon calorimeters used in the search for low mass dark matter or coherent neutrino-nucleus interactions have long observed a large excess of events below several hundred eV. The relaxation of damage created by the interaction of fast cosmic ray neutrons with the detector has been proposed as a source of these excess events. By comparing neutron exposed detectors to control detectors, we report the first measurement of phonon bursts caused by damage created by fast neutrons. Differences in the spectral shape, the rate dependence on thermal history, and the observed spectral rate scaled to the neutron exposure between irradiated and control detectors suggest that our observed LEE backgrounds are not dominated by neutron damage-induced phonon bursts.
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Submitted 18 March, 2026;
originally announced March 2026.
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Impact of refractive index heterogeneity on stimulated Brillouin scattering microscopy: a quantitative analysis
Authors:
Meng Xu,
Zixuan Du,
Yun Qi,
Jinrui Zhang,
Shuai Yao,
Robert Prevedel,
Fan Yang
Abstract:
Stimulated Brillouin scattering (SBS) microscopy enables label-free biomechanical imaging, with Brillouin gain serving as a critical contrast parameter for quantitative analysis. However, the influence of sample-induced refractive index (RI) heterogeneity on gain measurements remains poorly understood. Here, we quantitatively investigate, how RI mismatch affects SBS microscopy using finite element…
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Stimulated Brillouin scattering (SBS) microscopy enables label-free biomechanical imaging, with Brillouin gain serving as a critical contrast parameter for quantitative analysis. However, the influence of sample-induced refractive index (RI) heterogeneity on gain measurements remains poorly understood. Here, we quantitatively investigate, how RI mismatch affects SBS microscopy using finite element simulations and experiments on a phantom sample comprising polydimethylsiloxane beads embedded in agarose gel. We demonstrate that RI heterogeneity induces focal field distortion that reduce pump-probe beam overlap, resulting in attenuated Brillouin gain and degraded shift precision at material interfaces. Crucially, we establish that fiber-coupling efficiency, commonly used for system alignment, cannot serve as a linear proxy for Brillouin gain due to its heightened sensitivity to focal field distortion.
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Submitted 7 March, 2026;
originally announced March 2026.
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Topological Metamaterial for Magnetic Resonance Imaging
Authors:
Siyong Zheng,
Maopeng Wu,
Zhonghai Chi,
Xinxin Li,
Mingze Weng,
Fubei Liu,
Yingyi Qi,
Yi Yi,
Yakui Wang,
Jie Gao,
Guoxiang Zhan,
Zewen Chen,
Shuojun Ling,
Yucheng Wei,
Zhuozhao Zheng,
Qian Zhao,
Ji Zhou
Abstract:
Magnetic Resonance Imaging (MRI) is crucial in global healthcare, but the traditional receive coils, as a core component of MRI, SNR enhancement is limited due to the optimization of channel number and magnetic field strength faces high cost and complexity challenges. Here, we demonstrate the use of a topological material to enhance MRI signal reception. Designed with a stack of weak couplings, th…
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Magnetic Resonance Imaging (MRI) is crucial in global healthcare, but the traditional receive coils, as a core component of MRI, SNR enhancement is limited due to the optimization of channel number and magnetic field strength faces high cost and complexity challenges. Here, we demonstrate the use of a topological material to enhance MRI signal reception. Designed with a stack of weak couplings, this material forms quasi-two-dimensional dual topological boundary states. High properties are achieved through low-loss signal transmission via these topological states, as well as only enhanced local magnetic fields and increased number of channels. Initial tests demonstrate superior performance and accessibility compared to commercial coils, suggesting significant potential. This concept introduces a transformative paradigm for all MRI coil designs.
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Submitted 4 February, 2026;
originally announced February 2026.
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Bridging Photon Statistics and Phase Transitions in Random Fiber Lasers
Authors:
Yifei Qi,
Runhao Li,
Jie Li,
Taichao Wang,
Wangyouyou Li,
Ernesto P. Raposo,
Anderson S. L. Gomes,
Han Wu,
Zinan Wang
Abstract:
Complex systems exhibit rich equilibrium states, yet the universal principles governing these systems remain unrevealed, motivating the search for novel experimental platforms. Random fiber lasers (RFLs), which generate partially-coherent light-wave through feedback from Rayleigh scattering, provide a photonic realization of such systems. Here we report a comprehensive theoretical and experimental…
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Complex systems exhibit rich equilibrium states, yet the universal principles governing these systems remain unrevealed, motivating the search for novel experimental platforms. Random fiber lasers (RFLs), which generate partially-coherent light-wave through feedback from Rayleigh scattering, provide a photonic realization of such systems. Here we report a comprehensive theoretical and experimental investigation of photon statistics for RFLs based on classical second-order temporal correlation function \( g^{(2)}(τ) \), revealing unique statistical properties and introduce a two-dimensional framework for controlling photon statistics. Remarkably, we establish a unified landscape between photon correlation, intensity statistics governed by Levy statistics, and phase transitions with replica symmetry breaking. This multifaceted relationship, observed for the first time, bridges disordered photonics with statistical physics of complex system. Our results offer new pathways for engineering laser emission with controllable photon statistics, and more broadly, this work positions RFLs as a fertile land for exploring emergent behaviors in disordered systems.
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Submitted 18 January, 2026;
originally announced January 2026.
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A Pre-trained Reaction Embedding Descriptor Capturing Bond Transformation Patterns
Authors:
Weiqi Liu,
Fenglei Cao,
Yuan Qi,
Li-Cheng Xu
Abstract:
With the rise of data-driven reaction prediction models, effective reaction descriptors are crucial for bridging the gap between real-world chemistry and digital representations. However, general-purpose, reaction-wise descriptors remain scarce. This study introduces RXNEmb, a novel reaction-level descriptor derived from RXNGraphormer, a model pre-trained to distinguish real reactions from fictiti…
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With the rise of data-driven reaction prediction models, effective reaction descriptors are crucial for bridging the gap between real-world chemistry and digital representations. However, general-purpose, reaction-wise descriptors remain scarce. This study introduces RXNEmb, a novel reaction-level descriptor derived from RXNGraphormer, a model pre-trained to distinguish real reactions from fictitious ones with erroneous bond changes, thereby learning intrinsic bond formation and cleavage patterns. We demonstrate its utility by data-driven re-clustering of the USPTO-50k dataset, yielding a classification that more directly reflects bond-change similarities than rule-based categories. Combined with dimensionality reduction, RXNEmb enables visualization of reaction space diversity. Furthermore, attention weight analysis reveals the model's focus on chemically critical sites, providing mechanistic insight. RXNEmb serves as a powerful, interpretable tool for reaction fingerprinting and analysis, paving the way for more data-centric approaches in reaction analysis and discovery.
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Submitted 7 January, 2026;
originally announced January 2026.
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Pulsed heterodyne Brillouin detection enables high-resolution epi-detected biomechanical microscopy and endoscopy
Authors:
Zixuan Du,
Shuai Yao,
Yun Qi,
Jinrui Zhang,
Junlin You,
Yangxuan Liu,
Ting Mi,
Yun Luo,
Shiqing Cai,
Jingjing Xie,
Weibing Yang,
Zhisheng Yang,
Long Zhang,
Weibiao Chen,
Fan Yang
Abstract:
Brillouin microscopy enables non-contact, three-dimensional mapping of viscoelasticity in living systems, yet two long-standing limitations have constrained its biological reach: the lack of high-spectral-resolution epi-detection and the absence of practical fiber-compatible implementations. Here we introduce pulsed heterodyne Brillouin detection (PHBD), a coherent time-domain scheme addressing bo…
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Brillouin microscopy enables non-contact, three-dimensional mapping of viscoelasticity in living systems, yet two long-standing limitations have constrained its biological reach: the lack of high-spectral-resolution epi-detection and the absence of practical fiber-compatible implementations. Here we introduce pulsed heterodyne Brillouin detection (PHBD), a coherent time-domain scheme addressing both challenges. By combining high-peak-power pulsed excitation with shot-noise-limited detection, PHBD reduces the optical dose by approximately two orders of magnitude relative to continuous-wave heterodyne approaches. In an epi-microscope configuration, PHBD attains a spectral resolution of 27 MHz, a tenfold improvement over state-of-the-art Brillouin microscopes, enabling high-specificity, low-phototoxicity imaging of live cells and complex tissues. In an endoscopic configuration, coherent gating rejects parasitic Brillouin background from the delivery fiber, accelerating acquisition by two to three orders of magnitude over previous fiber-optic Brillouin endoscopes. Together, these capabilities establish a unified platform for single-ended, fiber-compatible Brillouin biomechanics, extending mechanical imaging and spectroscopy from cells to deep tissues via minimally invasive probes.
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Submitted 23 May, 2026; v1 submitted 15 November, 2025;
originally announced November 2025.
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FeaGPT: an End-to-End agentic-AI for Finite Element Analysis
Authors:
Yupeng Qi,
Ran Xu,
Xu Chu
Abstract:
Large language models (LLMs) are establishing new paradigms for engineering applications by enabling natural language control of complex computational workflows. This paper introduces FeaGPT, the first framework to achieve complete geometry-mesh-simulation workflows through conversational interfaces. Unlike existing tools that automate individual FEA components, FeaGPT implements a fully integrate…
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Large language models (LLMs) are establishing new paradigms for engineering applications by enabling natural language control of complex computational workflows. This paper introduces FeaGPT, the first framework to achieve complete geometry-mesh-simulation workflows through conversational interfaces. Unlike existing tools that automate individual FEA components, FeaGPT implements a fully integrated Geometry-Mesh-Simulation-Analysis (GMSA) pipeline that transforms engineering specifications into validated computational results without manual intervention. The system interprets engineering intent, automatically generates physics-aware adaptive meshes, configures complete FEA simulations with proper boundary condition inference, and performs multi-objective analysis through closed-loop iteration.
Experimental validation confirms complete end-to-end automation capability. Industrial turbocharger cases (7-blade compressor and 12-blade turbine at \SI{110000}{rpm}) demonstrate the system successfully transforms natural language specifications into validated CalculiX simulations, producing physically realistic results for rotating machinery analysis. Additional validation through 432 NACA airfoil configurations confirms scalability for parametric design exploration. These results demonstrate that natural language interfaces can effectively democratize access to advanced computational engineering tools while preserving analytical rigor.
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Submitted 24 October, 2025;
originally announced October 2025.
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Acoustic source depth estimation method based on a single hydrophone in Arctic underwater
Authors:
Jinbao Weng,
Yubo Qi,
Yanming Yang,
Hongtao Wen,
Hongtao Zhou,
Benqing Chen,
Dewei Xu,
Ruichao Xue,
Caigao Zeng
Abstract:
Based on the normal mode and ray theory, this article discusses the characteristics of surface sound source and reception at the surface layer, and explores depth estimation methods based on normal modes and rays, and proposes a depth estimation method based on the upper limit of modal frequency. Data verification is conducted to discuss the applicability and limitations of different methods. For…
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Based on the normal mode and ray theory, this article discusses the characteristics of surface sound source and reception at the surface layer, and explores depth estimation methods based on normal modes and rays, and proposes a depth estimation method based on the upper limit of modal frequency. Data verification is conducted to discuss the applicability and limitations of different methods. For the surface refracted normal mode waveguide, modes can be separated through warping transformation. Based on the characteristics of normal mode amplitude variation with frequency and number, the sound source depth can be estimated by matching amplitude information. Based on the spatial variation characteristics of eigenfunctions with frequency, a sound source depth estimation method matching the cutoff frequency of normal modes is proposed. For the deep Arctic sea, the sound ray arrival structure at the receiving end is obtained through the analysis of deep inversion sound ray trajectories, and the sound source depth can be estimated by matching the time difference of ray arrivals. Experimental data is used to verify the sound field patterns and the effectiveness of the sound source depth estimation method.
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Submitted 13 August, 2025; v1 submitted 9 August, 2025;
originally announced August 2025.
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Inversion of Arctic dual-channel sound speed profile based on random airgun signal
Authors:
Jinbao Weng,
Yubo Qi,
Yanming Yang,
Hongtao Wen,
Hongtao Zhou,
Benqing Chen,
Dewei Xu,
Ruichao Xue,
Caigao Zeng
Abstract:
For the unique dual-channel sound speed profiles of the Canadian Basin and the Chukchi Plateau in the Arctic, based on the propagation characteristics of refracted normal modes under dual-channel sound speed profiles, an inversion method using refracted normal modes for dual-channel sound speed profiles is proposed. This method proposes a dual-parameter representation method for dual-channel sound…
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For the unique dual-channel sound speed profiles of the Canadian Basin and the Chukchi Plateau in the Arctic, based on the propagation characteristics of refracted normal modes under dual-channel sound speed profiles, an inversion method using refracted normal modes for dual-channel sound speed profiles is proposed. This method proposes a dual-parameter representation method for dual-channel sound speed profiles, tailored to the characteristics of dual-channel sound speed profiles. A dispersion structure extraction method is proposed for the dispersion structure characteristics of refracted normal modes under dual-channel sound speed profiles. Combining the parameter representation method of sound speed profiles and the dispersion structure extraction method, an inversion method for dual-channel sound speed profiles is proposed. For the common horizontal variation of sound speed profiles in long-distance acoustic propagation, a method for inverting horizontally varying dual-channel sound speed profiles is proposed. Finally, this article verifies the effectiveness of the dual-channel sound speed profile inversion method using the Arctic low-frequency long-range acoustic propagation experiment. Compared with previous sound speed profile inversion methods, the method proposed in this article has the advantages of fewer inversion parameters and faster inversion speed. It can be implemented using only a single hydrophone passively receiving random air gun signals, and it also solves the inversion problem of horizontal variation of sound speed profiles. It has significant advantages such as low cost, easy deployment, and fast computation speed.
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Submitted 13 August, 2025; v1 submitted 9 August, 2025;
originally announced August 2025.
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Observation of a Knotted Electron Diffusion Region in Earth's Magnetotail Reconnection
Authors:
Xinmin Li,
Chuanfei Dong,
Hantao Ji,
Chi Zhang,
Liang Wang,
Barbara Giles,
Hongyang Zhou,
Rui Chen,
Yi Qi
Abstract:
Magnetic reconnection is a fundamental plasma process that alters the magnetic field topology and releases magnetic energy. Most numerical simulations and spacecraft observations assume a two-dimensional diffusion region, with the electron diffusion region (EDR) embedded in the same plane as the ion diffusion region (IDR) and a uniform guide field throughout. Using observations from Magnetospheric…
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Magnetic reconnection is a fundamental plasma process that alters the magnetic field topology and releases magnetic energy. Most numerical simulations and spacecraft observations assume a two-dimensional diffusion region, with the electron diffusion region (EDR) embedded in the same plane as the ion diffusion region (IDR) and a uniform guide field throughout. Using observations from Magnetospheric Multiscale (MMS) mission, we report a non-coplanar, knotted EDR in Earth's magnetotail current sheet. The reconnection plane of the knotted EDR deviates by approximately 38° from that of the IDR, with the guide field exhibiting both a 38° directional shift and a twofold increase in amplitude. Moreover, the Hall magnetic field is bipolar in the EDR but quadrupolar in the IDR, indicating different Hall current structures at electron and ion scales. These observations highlight the importance of three-dimensional effects and illustrate the complexity of multiscale coupling between the EDR and IDR during reconnection studies.1
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Submitted 14 July, 2025;
originally announced July 2025.
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Photonic chiral bulk transports manipulated by boundary freedom in three-dimensional meta-crystals
Authors:
Yingxin Qi,
Hanyu Wang,
Qinghua Guo,
Zhihong Zhu,
Biao Yang
Abstract:
In topological physics, one of the most intriguing phenomena is the presence of topological boundary states, accurately predicted by the well-established bulk-edge correspondence. For example, in three-dimensional Weyl semimetals, Fermi arcs emerge to connect projected Weyl points on the surface due to inheriting the bulk-edge correspondence from the integer quantum Hall effect. However, limited a…
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In topological physics, one of the most intriguing phenomena is the presence of topological boundary states, accurately predicted by the well-established bulk-edge correspondence. For example, in three-dimensional Weyl semimetals, Fermi arcs emerge to connect projected Weyl points on the surface due to inheriting the bulk-edge correspondence from the integer quantum Hall effect. However, limited attention has been paid to exploring the reverse mechanism in topological crystals. In this study, we propose that boundaries can serve as an alternative degree of freedom to manipulate topological bulk transports. We analytically and experimentally validate our concept using a finite-thickness photonic meta-crystal that supports bulk nodal lines, with its zeroth modes exhibiting opposite chiral bulk transports under different boundary conditions. Notably, the mirror symmetry remains preserved across both configurations. These findings are applicable to other topological systems, providing new insights into systems with varied boundary conditions and offering the potential for the design of more compact and spatially efficient topological photonic devices.
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Submitted 12 June, 2025;
originally announced June 2025.
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Study of Stability and Consistency of EAS Thermal Neutron Detection at ENDA-64
Authors:
Heng-Yu Zhang,
Xin-Hua Ma,
Tian-Lu Chen,
Shu-Wang Cui,
Danzengluobu,
Wei Gao,
Wen-Chao Gao,
Xin-Rui Gao,
Zi-Ao Gong,
Hai-Bing Hu,
Denis Kuleshov,
Kirill Kurinov,
Bing-Bing Li,
Fan-Ping Li,
Jia-Heng Li,
Yang Li,
Hu Liu,
Mao-Yuan Liu,
Ye Liu,
Xi-An Pan,
Da-Yu Peng,
Yao-Hui Qi,
Dong Qu,
Oleg Shchegolev,
Yuri Stenkin
, et al. (5 additional authors not shown)
Abstract:
Introduction:Electron-Neutron Detector Array (ENDA) is designed to measure thermal neutrons produced by hadronic interactions between cosmic ray extensive air showers (EAS) and the surrounding environment as well as electrons around the cores of EAS. ENDA is located within Large High Altitude Air Shower Observatory (LHAASO). ENDA was expanded from an initial 16 detectors to 64 detectors in April 2…
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Introduction:Electron-Neutron Detector Array (ENDA) is designed to measure thermal neutrons produced by hadronic interactions between cosmic ray extensive air showers (EAS) and the surrounding environment as well as electrons around the cores of EAS. ENDA is located within Large High Altitude Air Shower Observatory (LHAASO). ENDA was expanded from an initial 16 detectors to 64 detectors in April 2023, so called ENDA-64, and has been running alongside LHAASO. The stability and consistency of neutron detection are crucial for laying a solid foundation for subsequent data analysis and physical results. Methods:We obtain the stability by studying variations of event rate and thermal neutron rate in each cluster and the consistency by comparing distribution of number of thermal neutrons between clusters. Additionally, we investigate the specific influences of the rainy and dry seasons, as well as the presence or absence of sand cubes under the detectors, to examine the environmental factors affecting neutron measurement performance. Results:The calibration results indicate good consistency in thermal neutron detection across the clusters, with the maximum inconsistency of 6.85%. The maximum instability of event rate and thermal neutron rate over time are 4.68% and 11.0% respectively. The maximum inconsistency between the clusters without the sand cubes is 18%. The use of sand cubes is effective in protecting the target material from rainwater, and the sand cubes help the cluster to increase collection of neutrons generated by EAS events.
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Submitted 12 June, 2025;
originally announced June 2025.
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Thermal superscatterer: amplification of thermal scattering signatures for arbitrarily shaped thermal materials
Authors:
Yichao Liu,
Yawen Qi,
Fei Sun,
Jinyuan Shan,
Hanchuan Chen,
Yuying Hao,
Hongmin Fei,
Binzhao Cao,
Xin Liu,
Zhuanzhuan Huo
Abstract:
The concept of superscattering is extended to the thermal field through the design of a thermal superscatterer based on transformation thermodynamics. A small thermal scatterer of arbitrary shape and conductivity is encapsulated with an engineered negative-conductivity shell, creating a composite that mimics the scattering signature of a significantly larger scatterer. The amplified signature can…
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The concept of superscattering is extended to the thermal field through the design of a thermal superscatterer based on transformation thermodynamics. A small thermal scatterer of arbitrary shape and conductivity is encapsulated with an engineered negative-conductivity shell, creating a composite that mimics the scattering signature of a significantly larger scatterer. The amplified signature can match either a conformal larger scatterer (preserving conductivity) or a geometry-transformed one (modified conductivity). The implementation employs a positive-conductivity shell integrated with active thermal metasurfaces, demonstrated through three representative examples: super-insulating thermal scattering, super-conducting thermal scattering, and equivalent thermally transparent effects. Experimental validation shows the fabricated superscatterer amplifies the thermal scattering signature of a small insulated circular region by nine times, effectively mimicking the scattering signature of a circular region with ninefold radius. This approach enables thermal signature manipulation beyond physical size constraints, with potential applications in thermal superabsorbers/supersources, thermal camouflage, and energy management.
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Submitted 18 May, 2025;
originally announced June 2025.
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Spontaneous generation of athermal phonon bursts within bulk silicon causing excess noise, low energy background events and quasiparticle poisoning in superconducting sensors
Authors:
C. L. Chang,
Y. -Y. Chang,
M. Garcia-Sciveres,
W. Guo,
S. A. Hertel,
X. Li,
J. Lin,
M. Lisovenko,
R. Mahapatra,
W. Matava,
D. N. McKinsey,
P. K. Patel,
B. Penning,
M. Platt,
M. Pyle,
Y. Qi,
M. Reed,
I. Rydstrom,
R. K. Romani,
B. Sadoulet,
B. Serfass,
P. Sorensen,
B. Suerfu,
V. Velan,
G. Wang
, et al. (3 additional authors not shown)
Abstract:
Solid state phonon detectors used in the search for dark matter and coherent neutrino nucleus interactions (CE$ν$NS) require excellent energy resolution (eV-scale or below) and low backgrounds. An unknown source of phonon bursts, the low energy excess (LEE), dominates other above-threshold backgrounds and generates excess shot noise from sub-threshold bursts. In this paper, we measure these phonon…
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Solid state phonon detectors used in the search for dark matter and coherent neutrino nucleus interactions (CE$ν$NS) require excellent energy resolution (eV-scale or below) and low backgrounds. An unknown source of phonon bursts, the low energy excess (LEE), dominates other above-threshold backgrounds and generates excess shot noise from sub-threshold bursts. In this paper, we measure these phonon bursts for 12 days after cooldown in two nearly identical 1 cm$^2$ silicon detectors that differ only in the thickness of their substrate (1 mm vs. 4 mm thick). We find that both the channel-correlated shot noise and near-threshold shared LEE relax with time since cooldown. Additionally, both the correlated shot noise and LEE rates scale linearly with substrate thickness. When combined with previous measurements of other silicon phonon detectors with different substrate geometries and mechanical support strategies, these measurements strongly suggest that the dominant source of both above and below threshold LEE is the bulk substrate. By monitoring the relation between bias power and excess phonon shot noise, we estimate that the energy scale for sub-threshold noise events is $0.68 \pm 0.38$ meV. In our final dataset, we report a world-leading energy resolution of 258.5$\pm$0.4 meV in the 1 mm thick detector. Simple calculations suggest that these silicon substrate phonon bursts are likely a significant source of quasiparticle poisoning in superconducting qubits operated in well shielded and vibration free environments.
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Submitted 2 October, 2025; v1 submitted 21 May, 2025;
originally announced May 2025.
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The 2D Materials Roadmap
Authors:
Wencai Ren,
Peter Bøggild,
Joan Redwing,
Kostya Novoselov,
Luzhao Sun,
Yue Qi,
Kaicheng Jia,
Zhongfan Liu,
Oliver Burton,
Jack Alexander-Webber,
Stephan Hofmann,
Yang Cao,
Yu Long,
Quan-Hong Yang,
Dan Li,
Soo Ho Choi,
Ki Kang Kim,
Young Hee Lee,
Mian Li,
Qing Huang,
Yury Gogotsi,
Nicholas Clark,
Amy Carl,
Roman Gorbachev,
Thomas Olsen
, et al. (48 additional authors not shown)
Abstract:
Over the past two decades, 2D materials have rapidly evolved into a diverse and expanding family of material platforms. Many members of this materials class have demonstrated their potential to deliver transformative impact on fundamental research and technological applications across different fields. In this roadmap, we provide an overview of the key aspects of 2D material research and developme…
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Over the past two decades, 2D materials have rapidly evolved into a diverse and expanding family of material platforms. Many members of this materials class have demonstrated their potential to deliver transformative impact on fundamental research and technological applications across different fields. In this roadmap, we provide an overview of the key aspects of 2D material research and development, spanning synthesis, properties and commercial applications. We specifically present roadmaps for high impact 2D materials, including graphene and its derivatives, transition metal dichalcogenides, MXenes as well as their heterostructures and moiré systems. The discussions are organized into thematic sections covering emerging research areas (e.g., twisted electronics, moiré nano-optoelectronics, polaritronics, quantum photonics, and neuromorphic computing), breakthrough applications in key technologies (e.g., 2D transistors, energy storage, electrocatalysis, filtration and separation, thermal management, flexible electronics, sensing, electromagnetic interference shielding, and composites) and other important topics (computational discovery of novel materials, commercialization and standardization). This roadmap focuses on the current research landscape, future challenges and scientific and technological advances required to address, with the intent to provide useful references for promoting the development of 2D materials.
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Submitted 28 April, 2025; v1 submitted 28 March, 2025;
originally announced March 2025.
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First Limits on Light Dark Matter Interactions in a Low Threshold Two Channel Athermal Phonon Detector from the TESSERACT Collaboration
Authors:
C. L. Chang,
Y. -Y. Chang,
L. Chaplinsky,
C. W. Fink,
M. Garcia-Sciveres,
W. Guo,
S. A. Hertel,
X. Li,
J. Lin,
M. Lisovenko,
R. Mahapatra,
W. Matava,
D. N. McKinsey,
V. Novati,
P. K. Patel,
B. Penning,
H. D. Pinckney,
M. Platt,
M. Pyle,
Y. Qi,
M. Reed,
G. R. C Rischbieter,
R. K. Romani,
B. Sadoulet,
B. Serfass
, et al. (23 additional authors not shown)
Abstract:
We present results of a search for spin-independent dark matter-nucleon interactions in a 1 cm$^2$ by 1 mm thick (0.233 gram) high-resolution silicon athermal phonon detector operated above ground. For interactions in the substrate, this detector achieves a r.m.s. baseline energy resolution of 361.5 $\pm$ 0.4 MeV/$c^2$, the best for any athermal phonon detector to date. With an exposure of 0.233g…
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We present results of a search for spin-independent dark matter-nucleon interactions in a 1 cm$^2$ by 1 mm thick (0.233 gram) high-resolution silicon athermal phonon detector operated above ground. For interactions in the substrate, this detector achieves a r.m.s. baseline energy resolution of 361.5 $\pm$ 0.4 MeV/$c^2$, the best for any athermal phonon detector to date. With an exposure of 0.233g $\times$ 12 hours, we place the most stringent constraints on dark matter masses between 44 and 87 MeV/$c^2$, with the lowest unexplored cross section of 4 $\times 10^{-32}$ cm$^2$ at 87 MeV/$c^2$. We employ a conservative salting technique to reach the lowest dark matter mass ever probed via direct detection experiment. This constraint is enabled by two-channel rejection of low-energy backgrounds that are coupled to individual sensors.
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Submitted 28 March, 2025; v1 submitted 5 March, 2025;
originally announced March 2025.
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Fiber-based Ultra-High Speed Diffuse Speckle Contrast Analysis System for Deep Blood Flow Sensing Using a Large SPAD Camera
Authors:
Quan Wang,
Renzhe Bi,
Songhua Zheng,
Ahmet T. Erdogan,
Yi Qi,
Chenxu Li,
Yuanyuan Hua,
Mingliang Pan,
Yining Wang,
Neil Finlayson,
Malini Olivo,
Robert K. Henderson,
David Uei-Day Li
Abstract:
Diffuse speckle contrast analysis (DSCA), also called speckle contrast optical spectroscopy(SCOS), has emerged as a groundbreaking optical imaging technique for tracking dynamic biological processes, including blood flow and tissue perfusion. Recent advancements in single-photon avalanche diode (SPAD) cameras have unlocked exceptional capabilities in sensitivity, time resolution, and high frame ra…
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Diffuse speckle contrast analysis (DSCA), also called speckle contrast optical spectroscopy(SCOS), has emerged as a groundbreaking optical imaging technique for tracking dynamic biological processes, including blood flow and tissue perfusion. Recent advancements in single-photon avalanche diode (SPAD) cameras have unlocked exceptional capabilities in sensitivity, time resolution, and high frame rate imaging. Despite this, the application of large-format SPAD arrays in speckle contrast analysis is still relatively uncommon. In this study, we introduce a pioneering use of a large format SPAD camera for DSCA. By harnessing the camera's high temporal resolution and photon detection efficiency, we significantly enhance the accuracy and robustness of speckle contrast measurements. Our experimental results demonstrate the system's remarkable ability to capture rapid temporal variations over a broad field of view, enabling detailed spatiotemporal analysis. Through simulations, phantom experiments, and in vivo studies, we validate the approach's potential for a wide range of biomedical applications, such as cuff occlusion tests and functional tissue monitoring. This work highlights the transformative impact of large SPAD cameras on DSCA, paving the way for new breakthroughs in optical imaging.
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Submitted 27 February, 2025;
originally announced February 2025.
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Optimal signal transmission and timescale diversity in a model of human brain operating near criticality
Authors:
Yang Qi,
Jiexiang Wang,
Weiyang Ding,
Gustavo Deco,
Viktor Jirsa,
Wenlian Lu,
Jianfeng Feng
Abstract:
Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional circuit dynamics as well as cross-regional connectome may contribute to this timescale diversity. Equally important to diverse timescales is the ability to tran…
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Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional circuit dynamics as well as cross-regional connectome may contribute to this timescale diversity. Equally important to diverse timescales is the ability to transmit sensory signals reliably across the whole brain. Therefore, the brain must be able to generate diverse timescales while simultaneously minimizing signal attenuation. To understand the dynamical mechanism behind these phenomena, we develop a second-order mean field model of the human brain by applying moment closure and coarse-graining to a digital twin brain model endowed with whole brain structural connectome. Cross-regional coupling strength is found to induced a phase transition from asynchronous activity to synchronous oscillation. By analyzing the input-response properties of the model, we reveal criticality as a unifying mechanism for enabling simultaneously optimal signal transmission and timescales diversity. We show how structural connectome and criticality jointly shape intrinsic timescale hierarchy across the brain.
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Submitted 22 December, 2024;
originally announced December 2024.
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Small-scale dynamics and structure of free-surface turbulence
Authors:
Yinghe Qi,
Yaxing Li,
Filippo Coletti
Abstract:
The dynamics of small-scale structures in free-surface turbulence is crucial to large-scale phenomena in natural and industrial environments. Here we conduct experiments on the quasi-flat free surface of a zero-mean-flow turbulent water tank over the Reynolds number range $Re_λ = 207\textrm{--}312$. By seeding microscopic floating particles at high concentrations, the fine scales of the flow and t…
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The dynamics of small-scale structures in free-surface turbulence is crucial to large-scale phenomena in natural and industrial environments. Here we conduct experiments on the quasi-flat free surface of a zero-mean-flow turbulent water tank over the Reynolds number range $Re_λ = 207\textrm{--}312$. By seeding microscopic floating particles at high concentrations, the fine scales of the flow and the velocity gradient tensor are resolved. A kinematic relation is derived expressing the contribution of surface divergence and vorticity to the dissipation rate. The probability density functions of divergence, vorticity and strain-rate collapse once normalized by the Kolmogorov scales. Their magnitude displays strong intermittency and follows chi-square distributions with power-law tails at small values. The topology of high-intensity events and two-point statistics indicate that the surface divergence is characterized by dissipative spatial and temporal scales, while the high-vorticity and high-strain-rate regions are larger, long-lived, concurrent, and elongated. The second-order velocity structure functions obey the classic Kolmogorov scaling in the inertial range when the dissipation rate on the surface is considered, with a different numerical constant than in 3D turbulence. The cross-correlation among divergence, vorticity and strain-rate indicates that the surface-attached vortices are strengthened during downwellings and diffuse when those dissipate. Sources (sinks) in the surface velocity fields are associated with strong (weak) surface-parallel stretching and compression along perpendicular directions. The floating particles cluster over spatial and temporal scales larger than those of the sinks. These results demonstrate that, compared to 3D turbulence, in free-surface turbulence the energetic scales leave a stronger imprint on the small-scale quantities.
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Submitted 5 December, 2024;
originally announced December 2024.
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Restricted Euler dynamics in free-surface turbulence
Authors:
Yinghe Qi,
Zhenwei Xu,
Filippo Coletti
Abstract:
The small-scale velocity gradient is connected to fundamental properties of turbulence at the large scales. By neglecting the viscous and nonlocal pressure Hessian terms, we derive a restricted Euler model for the turbulent flow along an undeformed free surface and discuss the associated stable/unstable manifolds. The model is compared with the data collected by high-resolution imaging on the free…
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The small-scale velocity gradient is connected to fundamental properties of turbulence at the large scales. By neglecting the viscous and nonlocal pressure Hessian terms, we derive a restricted Euler model for the turbulent flow along an undeformed free surface and discuss the associated stable/unstable manifolds. The model is compared with the data collected by high-resolution imaging on the free surface of a turbulent water tank with negligible surface waves. The joint probability density function (PDF) of the velocity gradient invariants exhibits a distinct pattern from the one in the bulk. The restricted Euler model captures the enhanced probability along the unstable branch of the manifold and the asymmetry of the joint PDF. Significant deviations between the experiments and the prediction are evident, however, in particular concerning the compressibility of the surface flow. These results highlight the enhanced intermittency of the velocity gradient and the influence of the free surface on the energy cascade.
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Submitted 4 December, 2024;
originally announced December 2024.
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Advances in understanding vacuum break dynamics in liquid helium-cooled tubes for accelerator beamline applications
Authors:
Yinghe Qi,
Wei Guo
Abstract:
Understanding air propagation and condensation following a catastrophic vacuum break in particle accelerator beamlines cooled by liquid helium is essential for ensuring operational safety. This review summarizes experimental and theoretical work conducted in our cryogenics lab to address this issue. Systematic measurements were performed to study nitrogen gas propagation in uniform copper tubes co…
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Understanding air propagation and condensation following a catastrophic vacuum break in particle accelerator beamlines cooled by liquid helium is essential for ensuring operational safety. This review summarizes experimental and theoretical work conducted in our cryogenics lab to address this issue. Systematic measurements were performed to study nitrogen gas propagation in uniform copper tubes cooled by both normal liquid helium (He I) and superfluid helium (He II). These experiments revealed a nearly exponential deceleration of the gas front, with stronger deceleration observed in He II-cooled tubes. To interpret these results, a one-dimensional (1D) theoretical model was developed, incorporating gas dynamics, heat transfer, and condensation mechanisms. The model successfully reproduced key experimental observations in the uniform tube system. However, recent experiments involving a bulky copper cavity designed to mimic the geometry of a superconducting radio-frequency (SRF) cavity revealed strong anisotropic flow patterns of nitrogen gas within the cavity, highlighting limitations in extrapolating results from simplified tube geometries to real accelerator beamlines. To address these complexities, we outline plans for systematic studies using tubes with multiple bulky cavities and the development of a two-dimensional (2D) model to simulate gas dynamics in these more intricate configurations. These efforts aim to provide a comprehensive understanding of vacuum breaks in particle accelerators and improve predictive capabilities for their operational safety.
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Submitted 23 November, 2024;
originally announced November 2024.
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Particle Levitation Velocimetry for boundary layer measurements in high Reynolds number liquid helium turbulence
Authors:
Yinghe Qi,
Wei Guo
Abstract:
Understanding boundary layer flows in high Reynolds number (Re) turbulence is crucial for advancing fluid dynamics in a wide range of applications, from improving aerodynamic efficiency in aviation to optimizing energy systems in industrial processes. However, generating such flows requires complex, power-intensive large-scale facilities. Furthermore, the use of local probes, such as hot wires and…
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Understanding boundary layer flows in high Reynolds number (Re) turbulence is crucial for advancing fluid dynamics in a wide range of applications, from improving aerodynamic efficiency in aviation to optimizing energy systems in industrial processes. However, generating such flows requires complex, power-intensive large-scale facilities. Furthermore, the use of local probes, such as hot wires and pressure sensors, often introduces disturbances due to the necessary support structures, compromising measurement accuracy. In this paper, we present a solution that leverages the vanishingly small viscosity of liquid helium to produce high Re flows, combined with an innovative Particle Levitation Velocimetry (PLV) system for precise flow-field measurements. This PLV system uses magnetically levitated superconducting micro-particles to measure the near-wall velocity field in liquid helium. Through comprehensive theoretical analysis, we demonstrate that the PLV system enables quantitative measurements of the velocity boundary layer over a wall unit range of $44\le y^{+}\le 4400$, with a spatial resolution that, depending on the particle size, can reach down to about 10~$μ$m. This development opens new avenues for exploring turbulence structures and correlations within the thin boundary layer that would be otherwise difficult to achieve.
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Submitted 7 November, 2024;
originally announced November 2024.
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Topological Dirac-vortex modes in a three-dimensional photonic topological insulator
Authors:
Bei Yan,
Yingfeng Qi,
Ziyao Wang,
Yan Meng,
Linyun Yang,
Zhen-Xiao Zhu,
Jing-Ming Chen,
Yuxin Zhong,
Min-Qi Cheng,
Xiang Xi,
Zhen Gao
Abstract:
Recently, topological Dirac-vortex modes in Kekulé-distorted photonic lattices have attracted broad interest and exhibited promising applications in robust photonic devices such as topological cavities, lasers, and fibers. However, due to the vectorial nature of electromagnetic waves that results in complicated band dispersions and fails the tight-binding model predictions, it is challenging to co…
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Recently, topological Dirac-vortex modes in Kekulé-distorted photonic lattices have attracted broad interest and exhibited promising applications in robust photonic devices such as topological cavities, lasers, and fibers. However, due to the vectorial nature of electromagnetic waves that results in complicated band dispersions and fails the tight-binding model predictions, it is challenging to construct three-dimensional (3D) topological photonic structures with Kekulé distortion and the photonic topological Dirac-vortex modes have thus far been limited to two-dimensional (2D) systems. Here, by directly mapping a 3D Kekulé-distorted tight-binding model in a 3D tight-binding-like photonic crystal exhibiting scalar-wave-like band structures, we theoretically propose and experimentally demonstrate topological Dirac-vortex modes in a 3D photonic topological insulator for the first time. Using microwave near-field measurements, we directly observe robust photonic topological Dirac-vortex modes bound to and propagate along a one-dimensional (1D) Dirac-vortex line defect, matching well with the tight-binding and simulation results. Our work offers an ideal platform to map tight-binding models in 3D topological photonic crystals directly and opens a new avenue for exploiting topological lattice defects to manipulate light in 3D space.
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Submitted 6 November, 2024;
originally announced November 2024.
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Intermittency of bubble deformation in turbulence
Authors:
Xu Xu,
Yinghe Qi,
Shijie Zhong,
Shiyong Tan,
Qianwen Wu,
Rui Ni
Abstract:
The deformation of finite-sized bubbles in intense turbulence exhibits complex geometries beyond simple spheroids as the bubbles exchange energy with the surrounding eddies across a wide range of scales. This study investigates deformation via the velocity of the most stretched tip of the deformed bubble in 3D, as the tip extension results from the compression of the rest of the interface by surro…
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The deformation of finite-sized bubbles in intense turbulence exhibits complex geometries beyond simple spheroids as the bubbles exchange energy with the surrounding eddies across a wide range of scales. This study investigates deformation via the velocity of the most stretched tip of the deformed bubble in 3D, as the tip extension results from the compression of the rest of the interface by surrounding eddies. The results show that the power spectrum based on the tip velocity exhibits a scaling akin to that of the Lagrangian statistics of fluid elements, but decays with a distinct timescale and magnitude modulated by the Weber number based on the bubble size. This indicates that the interfacial energy is primarily siphoned from eddies of similar sizes as the bubble. Moreover, the tip velocity appears much more intermittent than the velocity increment, and its distribution near the extreme tails can be explained by the proposed model that accounts for the fact that small eddies with sufficient energy can contribute to extreme deformation. These findings provide a framework for understanding the energy transfer between deformable objects and multiscale eddies in intense turbulence.
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Submitted 28 October, 2024;
originally announced October 2024.
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Analytical solutions of layered Poiseuille flows in the diffuse interface model
Authors:
Jun Lai,
Yiming Qi,
Lian-Ping Wang
Abstract:
Based on the two-phase macroscopic governing equations in the phase field model, the governing equations and analytical solutions for the steady-state layered Poiseuille flows in the diffuse interface (DI) model are derived and analyzed. Then, based on three dynamic viscosity models commonly used in the literature, the corresponding analytical solutions of the velocity profile are obtained. Under…
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Based on the two-phase macroscopic governing equations in the phase field model, the governing equations and analytical solutions for the steady-state layered Poiseuille flows in the diffuse interface (DI) model are derived and analyzed. Then, based on three dynamic viscosity models commonly used in the literature, the corresponding analytical solutions of the velocity profile are obtained. Under the condition of high dynamic viscosity ratio, the analytical solution of DI model may be significantly different from that of the sharp interface (SI) model, and the degree of deviation depends on the dynamic viscosity model and the interface thickness. Therefore, the numerical simulation of layered Poiseuille flow with DI model should be compared with the analytical solution of DI model with the same dynamic viscosity model. A direct comparison of the numerical solution results with the SI analytical solution could misinterpret the model error with the numerical error. In addition, the direct numerical simulation data and the DI analytical solutions agree well, which validates the theoretical results. Finally, a new set of symmetrical dynamic viscosity models is proposed and recommended for the simulation of two-phase flows in the DI model, which makes both the viscosity profiles and velocity profiles close to the SI model.
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Submitted 25 October, 2024;
originally announced October 2024.
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Low Energy Backgrounds and Excess Noise in a Two-Channel Low-Threshold Calorimeter
Authors:
Robin Anthony-Petersen,
Clarence L. Chang,
Yen-Yung Chang,
Luke Chaplinsky,
Caleb W. Fink,
Maurice Garcia-Sciveres,
Wei Guo,
Scott A. Hertel,
Xinran Li,
Junsong Lin,
Marharyta Lisovenko,
Rupak Mahapatra,
William Matava,
Daniel N. McKinsey,
David Z. Osterman,
Pratyush K. Patel,
Bjoern Penning,
Mark Platt,
Matt Pyle,
Yinghe Qi,
Maggie Reed,
Ivar Rydstrom,
Roger K. Romani,
Bernard Sadoulet,
Bruno Serfass
, et al. (7 additional authors not shown)
Abstract:
We describe observations of low energy excess (LEE) events, background events observed in all light dark matter direct detection calorimeters, and noise in a Transition Edge Sensor based two-channel silicon athermal phonon detector with 375 meV baseline energy resolution. We measure two distinct LEE populations: ``shared'' multichannel events with a pulse shape consistent with substrate athermal p…
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We describe observations of low energy excess (LEE) events, background events observed in all light dark matter direct detection calorimeters, and noise in a Transition Edge Sensor based two-channel silicon athermal phonon detector with 375 meV baseline energy resolution. We measure two distinct LEE populations: ``shared'' multichannel events with a pulse shape consistent with substrate athermal phonon events, and sub-eV events that couple nearly exclusively to a single channel with a significantly faster pulse shape. These ``singles'' are consistent with events occurring within the aluminum athermal phonon collection fins. Similarly, our measured detector noise is higher than the theoretical expectation. Measured noise can be split into an uncorrelated component, consistent with shot noise from small energy depositions within the athermal phonon sensor itself, and a correlated component, consistent with shot noise from energy depositions within the silicon substrate's phonon system.
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Submitted 4 April, 2025; v1 submitted 21 October, 2024;
originally announced October 2024.
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Deep Learning-based Detection of Bacterial Swarm Motion Using a Single Image
Authors:
Yuzhu Li,
Hao Li,
Weijie Chen,
Keelan O'Riordan,
Neha Mani,
Yuxuan Qi,
Tairan Liu,
Sridhar Mani,
Aydogan Ozcan
Abstract:
Distinguishing between swarming and swimming, the two principal forms of bacterial movement, holds significant conceptual and clinical relevance. This is because bacteria that exhibit swarming capabilities often possess unique properties crucial to the pathogenesis of infectious diseases and may also have therapeutic potential. Here, we report a deep learning-based swarming classifier that rapidly…
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Distinguishing between swarming and swimming, the two principal forms of bacterial movement, holds significant conceptual and clinical relevance. This is because bacteria that exhibit swarming capabilities often possess unique properties crucial to the pathogenesis of infectious diseases and may also have therapeutic potential. Here, we report a deep learning-based swarming classifier that rapidly and autonomously predicts swarming probability using a single blurry image. Compared with traditional video-based, manually-processed approaches, our method is particularly suited for high-throughput environments and provides objective, quantitative assessments of swarming probability. The swarming classifier demonstrated in our work was trained on Enterobacter sp. SM3 and showed good performance when blindly tested on new swarming (positive) and swimming (negative) test images of SM3, achieving a sensitivity of 97.44% and a specificity of 100%. Furthermore, this classifier demonstrated robust external generalization capabilities when applied to unseen bacterial species, such as Serratia marcescens DB10 and Citrobacter koseri H6. It blindly achieved a sensitivity of 97.92% and a specificity of 96.77% for DB10, and a sensitivity of 100% and a specificity of 97.22% for H6. This competitive performance indicates the potential to adapt our approach for diagnostic applications through portable devices or even smartphones. This adaptation would facilitate rapid, objective, on-site screening for bacterial swarming motility, potentially enhancing the early detection and treatment assessment of various diseases, including inflammatory bowel diseases (IBD) and urinary tract infections (UTI).
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Submitted 19 October, 2024;
originally announced October 2024.
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Design Studies Of A Pulsed Quasimonoenergetic 2-keV Neutron Source For Calibration Of Low Threshold Dark Matter Detectors
Authors:
L. Chaplinsky,
S. Fiorucci,
C. W. Fink,
M. Garcia-Sciveres,
W. Guo,
S. A. Hertel,
J. K. Wuko,
X. Li,
J. Lin,
R. Mahapatra,
W. Matava,
D. N. McKinsey,
D. Z. Osterman,
P. K. Patel,
B. Penning,
H. D. Pinckney,
M. Platt,
Y. Qi,
M. Reed,
G. R. C Rischbieter,
R. K. Romani,
P. Sorensen,
V. Velan,
G. Wang,
Y. Wang
, et al. (2 additional authors not shown)
Abstract:
We describe design studies for a pulsed quasi-monoenergetic 2-keV neutron source for calibration of sub-keV nuclear recoils. Such a calibration is required for detectors sensitive to sub-GeV dark matter and also the coherent elastic scattering of reactor neutrinos. In our design, neutrons from a commercial deuterium-tritium generator are moderated to the keV scale and then filtered to the monoener…
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We describe design studies for a pulsed quasi-monoenergetic 2-keV neutron source for calibration of sub-keV nuclear recoils. Such a calibration is required for detectors sensitive to sub-GeV dark matter and also the coherent elastic scattering of reactor neutrinos. In our design, neutrons from a commercial deuterium-tritium generator are moderated to the keV scale and then filtered to the monoenergetic spectrum using a feature in the neutron cross section of scandium. In this approach, unmoderated high-energy neutrons form a challenging background, along with gammas from neutron capture in the moderator materials. We describe the optimization of the moderator+filter and shielding geometry, and find a geometry that in simulation achieves both the target neutron flux at 2 keV and subdominant rates of background interactions. Lastly, we describe a future path to lower-energy (few eV scale) calibrations using time-of-flight and sub-keV neutrons.
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Submitted 14 October, 2024;
originally announced October 2024.
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Label-free evaluation of lung and heart transplant biopsies using tissue autofluorescence-based virtual staining
Authors:
Yuzhu Li,
Nir Pillar,
Tairan Liu,
Guangdong Ma,
Yuxuan Qi,
Kevin de Haan,
Yijie Zhang,
Xilin Yang,
Adrian J. Correa,
Guangqian Xiao,
Kuang-Yu Jen,
Kenneth A. Iczkowski,
Yulun Wu,
William Dean Wallace,
Aydogan Ozcan
Abstract:
Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histological assessment is essential for the timely detection and diagnosis of transplant rejection and remains the gold standard. Nevertheless, the traditional histochemical staining process is time-consuming, costly, and la…
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Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histological assessment is essential for the timely detection and diagnosis of transplant rejection and remains the gold standard. Nevertheless, the traditional histochemical staining process is time-consuming, costly, and labor-intensive. Here, we present a panel of virtual staining neural networks for lung and heart transplant biopsies, which digitally convert autofluorescence microscopic images of label-free tissue sections into their brightfield histologically stained counterparts, bypassing the traditional histochemical staining process. Specifically, we virtually generated Hematoxylin and Eosin (H&E), Masson's Trichrome (MT), and Elastic Verhoeff-Van Gieson (EVG) stains for label-free transplant lung tissue, along with H&E and MT stains for label-free transplant heart tissue. Subsequent blind evaluations conducted by three board-certified pathologists have confirmed that the virtual staining networks consistently produce high-quality histology images with high color uniformity, closely resembling their well-stained histochemical counterparts across various tissue features. The use of virtually stained images for the evaluation of transplant biopsies achieved comparable diagnostic outcomes to those obtained via traditional histochemical staining, with a concordance rate of 82.4% for lung samples and 91.7% for heart samples. Moreover, virtual staining models create multiple stains from the same autofluorescence input, eliminating structural mismatches observed between adjacent sections stained in the traditional workflow, while also saving tissue, expert time, and staining costs.
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Submitted 6 July, 2025; v1 submitted 8 September, 2024;
originally announced September 2024.
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Spectral Informed Neural Network: An Efficient and Low-Memory PINN
Authors:
Tianchi Yu,
Yiming Qi,
Ivan Oseledets,
Shiyi Chen
Abstract:
With growing investigations into solving partial differential equations by physics-informed neural networks (PINNs), more accurate and efficient PINNs are required to meet the practical demands of scientific computing. One bottleneck of current PINNs is computing the high-order derivatives via automatic differentiation which often necessitates substantial computing resources. In this paper, we foc…
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With growing investigations into solving partial differential equations by physics-informed neural networks (PINNs), more accurate and efficient PINNs are required to meet the practical demands of scientific computing. One bottleneck of current PINNs is computing the high-order derivatives via automatic differentiation which often necessitates substantial computing resources. In this paper, we focus on removing the automatic differentiation of the spatial derivatives and propose a spectral-based neural network that substitutes the differential operator with a multiplication. Compared to the PINNs, our approach requires lower memory and shorter training time. Thanks to the exponential convergence of the spectral basis, our approach is more accurate. Moreover, to handle the different situations between physics domain and spectral domain, we provide two strategies to train networks by their spectral information. Through a series of comprehensive experiments, We validate the aforementioned merits of our proposed network.
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Submitted 8 October, 2024; v1 submitted 29 August, 2024;
originally announced August 2024.
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FuXi Weather: A data-to-forecast machine learning system for global weather
Authors:
Xiuyu Sun,
Xiaohui Zhong,
Xiaoze Xu,
Yuanqing Huang,
Hao Li,
J. David Neelin,
Deliang Chen,
Jie Feng,
Wei Han,
Libo Wu,
Yuan Qi
Abstract:
Weather forecasting traditionally relies on numerical weather prediction (NWP) systems that integrates global observational systems, data assimilation (DA), and forecasting models. Despite steady improvements in forecast accuracy over recent decades, further advances are increasingly constrained by high computational costs, the underutilization of vast observational datasets, and the challenges of…
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Weather forecasting traditionally relies on numerical weather prediction (NWP) systems that integrates global observational systems, data assimilation (DA), and forecasting models. Despite steady improvements in forecast accuracy over recent decades, further advances are increasingly constrained by high computational costs, the underutilization of vast observational datasets, and the challenges of obtaining finer resolution. These limitations, alongside the uneven distribution of observational networks, result in global disparities in forecast accuracy, leaving some regions vulnerable to extreme weather. Recent advances in machine learning present a promising alternative, providing more efficient and accurate forecasts using the same initial conditions as NWP. However, current machine learning models still depend on the initial conditions generated by NWP systems, which require extensive computational resources and expertise. Here we introduce FuXi Weather, a machine learning weather forecasting system that assimilates data from multiple satellites. Operating on a 6-hourly DA and forecast cycle, FuXi Weather generates reliable and accurate 10-day global weather forecasts at a spatial resolution of $0.25^\circ$. FuXi Weather is the first system to achieve all-grid, all-surface, all-channel, and all-sky DA and forecasting, extending skillful forecast lead times beyond those of the European Centre for Medium-range Weather Forecasts (ECMWF) high-resolution forecasts (HRES) while using significantly fewer observations. FuXi Weather consistently outperforms ECMWF HRES in observation-sparse regions, such as central Africa, demonstrating its potential to improve forecasts where observational infrastructure is limited.
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Submitted 18 November, 2024; v1 submitted 10 August, 2024;
originally announced August 2024.
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Study of the decay and production properties of $D_{s1}(2536)$ and $D_{s2}^*(2573)$
Authors:
M. Ablikim,
M. N. Achasov,
P. Adlarson,
O. Afedulidis,
X. C. Ai,
R. Aliberti,
A. Amoroso,
Q. An,
Y. Bai,
O. Bakina,
I. Balossino,
Y. Ban,
H. -R. Bao,
V. Batozskaya,
K. Begzsuren,
N. Berger,
M. Berlowski,
M. Bertani,
D. Bettoni,
F. Bianchi,
E. Bianco,
A. Bortone,
I. Boyko,
R. A. Briere,
A. Brueggemann
, et al. (645 additional authors not shown)
Abstract:
The $e^+e^-\rightarrow D_s^+D_{s1}(2536)^-$ and $e^+e^-\rightarrow D_s^+D^*_{s2}(2573)^-$ processes are studied using data samples collected with the BESIII detector at center-of-mass energies from 4.530 to 4.946~GeV. The absolute branching fractions of $D_{s1}(2536)^- \rightarrow \bar{D}^{*0}K^-$ and $D_{s2}^*(2573)^- \rightarrow \bar{D}^0K^-$ are measured for the first time to be…
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The $e^+e^-\rightarrow D_s^+D_{s1}(2536)^-$ and $e^+e^-\rightarrow D_s^+D^*_{s2}(2573)^-$ processes are studied using data samples collected with the BESIII detector at center-of-mass energies from 4.530 to 4.946~GeV. The absolute branching fractions of $D_{s1}(2536)^- \rightarrow \bar{D}^{*0}K^-$ and $D_{s2}^*(2573)^- \rightarrow \bar{D}^0K^-$ are measured for the first time to be $(35.9\pm 4.8\pm 3.5)\%$ and $(37.4\pm 3.1\pm 4.6)\%$, respectively. The measurements are in tension with predictions based on the assumption that the $D_{s1}(2536)$ and $D_{s2}^*(2573)$ are dominated by a bare $c\bar{s}$ component. The $e^+e^-\rightarrow D_s^+D_{s1}(2536)^-$ and $e^+e^-\rightarrow D_s^+D^*_{s2}(2573)^-$ cross sections are measured, and a resonant structure at around 4.6~GeV with a width of 50~MeV is observed for the first time with a statistical significance of $15σ$ in the $e^+e^-\rightarrow D_s^+D^*_{s2}(2573)^-$ process. It could be the $Y(4626)$ found by the Belle collaboration in the $D_s^+D_{s1}(2536)^{-}$ final state, since they have similar masses and widths. There is also evidence for a structure at around 4.75~GeV in both processes.
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Submitted 10 July, 2024;
originally announced July 2024.
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Electronic processes in collisions between nitrogen ions and hydrogen atoms
Authors:
C. C. Jia,
Y. Y. Qi,
J. J. Niu,
Y. Wu J. G. Wang,
A. Dubois,
N. Sisourat,
J. W. Gao
Abstract:
In order to interpret and predict the behavior and properties of fusion plasma, accurate cross sections for electronic processes in collisions between plasma impurities and atomic hydrogen are required. In this work, we investigate the electron capture (or charge exchange), target excitation, and ionization processes occurring in collision of ${\rm N}^{4+}$ with atomic hydrogen in a broad energy d…
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In order to interpret and predict the behavior and properties of fusion plasma, accurate cross sections for electronic processes in collisions between plasma impurities and atomic hydrogen are required. In this work, we investigate the electron capture (or charge exchange), target excitation, and ionization processes occurring in collision of ${\rm N}^{4+}$ with atomic hydrogen in a broad energy domain ranging from 0.06 to 225 keV/u. We consider ${\rm N}^{4+}$ ground state ${\rm N}^{4+} (2s)$ and also ${\rm N}^{4+} (2p)$ since the impurities in the edge plasma environment may be excited due to collisions with electrons and ions/atoms. Total and partial cross sections in both spin-averaged and spin-resolved cases are calculated using a two-active-electron semiclassical asymptotic-state close-coupling approach. For electron capture cross sections the present results show the best overall agreement with available experimental data for both total and partial cross sections, and the origins of observed discrepancies are discussed. Furthermore, we provide new data for target excitation and ionization processes, which are essential to improve our understanding of this relevant collision system.
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Submitted 6 September, 2024; v1 submitted 13 June, 2024;
originally announced June 2024.
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Data quality control system and long-term performance monitor of the LHAASO-KM2A
Authors:
Zhen Cao,
F. Aharonian,
Axikegu,
Y. X. Bai,
Y. W. Bao,
D. Bastieri,
X. J. Bi,
Y. J. Bi,
W. Bian,
A. V. Bukevich,
Q. Cao,
W. Y. Cao,
Zhe Cao,
J. Chang,
J. F. Chang,
A. M. Chen,
E. S. Chen,
H. X. Chen,
Liang Chen,
Lin Chen,
Long Chen,
M. J. Chen,
M. L. Chen,
Q. H. Chen,
S. Chen
, et al. (263 additional authors not shown)
Abstract:
The KM2A is the largest sub-array of the Large High Altitude Air Shower Observatory (LHAASO). It consists of 5216 electromagnetic particle detectors (EDs) and 1188 muon detectors (MDs). The data recorded by the EDs and MDs are used to reconstruct primary information of cosmic ray and gamma-ray showers. This information is used for physical analysis in gamma-ray astronomy and cosmic ray physics. To…
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The KM2A is the largest sub-array of the Large High Altitude Air Shower Observatory (LHAASO). It consists of 5216 electromagnetic particle detectors (EDs) and 1188 muon detectors (MDs). The data recorded by the EDs and MDs are used to reconstruct primary information of cosmic ray and gamma-ray showers. This information is used for physical analysis in gamma-ray astronomy and cosmic ray physics. To ensure the reliability of the LHAASO-KM2A data, a three-level quality control system has been established. It is used to monitor the status of detector units, stability of reconstructed parameters and the performance of the array based on observations of the Crab Nebula and Moon shadow. This paper will introduce the control system and its application on the LHAASO-KM2A data collected from August 2021 to July 2023. During this period, the pointing and angular resolution of the array were stable. From the observations of the Moon shadow and Crab Nebula, the results achieved using the two methods are consistent with each other. According to the observation of the Crab Nebula at energies from 25 TeV to 100 TeV, the time averaged pointing errors are estimated to be $-0.003^{\circ} \pm 0.005^{\circ}$ and $0.001^{\circ} \pm 0.006^{\circ}$ in the R.A. and Dec directions, respectively.
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Submitted 13 June, 2024; v1 submitted 20 May, 2024;
originally announced May 2024.