Showing 1–50 of 115 results for author: Brown, C

The comets discovered from New Zealand, and the astronomers who found them

Authors: John Drummond, Wayne Orchiston, Carolyn Brown, Jonathan Horner

Abstract: Eleven comets were discovered by six New Zealanders from New Zealand shores. New Zealand's important geographical position south of the Equator is highlighted. This location allows observers to discover and observe comets that would be difficult to see from the Northern Hemisphere. The lives of these comet discoverers are explored, as well as the discovery circumstances and an analysis of the morp… ▽ More Eleven comets were discovered by six New Zealanders from New Zealand shores. New Zealand's important geographical position south of the Equator is highlighted. This location allows observers to discover and observe comets that would be difficult to see from the Northern Hemisphere. The lives of these comet discoverers are explored, as well as the discovery circumstances and an analysis of the morphological changes of their comets. We find that numerous New Zealand observers made many observations of these comets, however, relatively few were included in international publications, this possibly being due to papers about them not being submitted to overseas journals. We also note an interesting trend in that the number of New Zealand newspaper articles relating to these comet discoveries plummeted after the 1946 discovery by Albert Jones. We speculate as to why this may have happened. △ Less

Submitted 20 August, 2026; originally announced August 2026.

Comments: Published in the Journal of Astronomical History and Heritage

Journal ref: Journal of Astronomical History and Heritage, 29(2), 287-366 (2026)

Phase-Space Energy Transfer of Wave-Particle Interactions using the Field-Particle Correlation Technique and Linear Plasma Theory with JET-PLUME

Authors: Collin R. Brown, Gregory G. Howes, Kristopher G. Klein, Jason M. TenBarge

Abstract: The collisionless transfer of energy between fields and particles through wave-particle interactions is a fundamental process in space plasmas but remains incompletely characterized because many mechanisms operate across a wide parameter range and diverse plasma conditions. The Field-Particle Correlation (FPC) technique reveals velocity-space signatures of particle energization by correlating meas… ▽ More The collisionless transfer of energy between fields and particles through wave-particle interactions is a fundamental process in space plasmas but remains incompletely characterized because many mechanisms operate across a wide parameter range and diverse plasma conditions. The Field-Particle Correlation (FPC) technique reveals velocity-space signatures of particle energization by correlating measured electric field fluctuations with changes in the velocity distribution. Fully mapping these signatures across plasma parameters requires an impractically large number of kinetic simulations or observations. To address this challenge, we introduce JET-PLUME (Judging Energy Transfer in a Plasma in a Linear Uniform Magnetized Environment), an extension of the PLUME Vlasov-Maxwell dispersion solver. JET-PLUME uses PLUME's ability to model parallel drifting bi-Maxwellian distributions to examine phase-space energy transfer by adding an analytic Fourier-space formulation of the FPC. This approach isolates the contribution of individual resonances, separates degenerate entropy mode components, and allows systematic analysis of unstable, growing modes. Dimensionless expressions extend the results across a broad parameter range and highlight the role of off-diagonal elements of the susceptibility tensor in coupling electric field and current response. We show that during kinetic Alfvén wave damping, the perpendicular field can drive parallel ion currents among particles with large perpendicular velocity, reducing the net Landau damping. The resulting velocity-space signatures, accessible through JET-PLUME, demonstrate how analytic formulations of phase-space energy transfer can reveal novel physics of wave-particle interactions across diverse plasma environments. △ Less

Submitted 18 June, 2026; originally announced June 2026.

Comments: 26 pages, 7 figures, and 6 tables. Accepted for publication in Physics of Plasmas

Radioactive Source Seeking using Bayesian Optimisation with Movement Penalty

Authors: Lysander Miller, Joshua Keene, Jeremy M. C. Brown, Airlie Chapman

Abstract: The use of mobile robotics in radioactive source seeking has become an important part of modern radiation-safety practices, supporting timely mitigation of contamination risks and helping protect public health. However, measuring radiation is often time-consuming, rendering traditional gradient-based source-seeking methods less effective due to lower sample efficiency. This paper proposes a sample… ▽ More The use of mobile robotics in radioactive source seeking has become an important part of modern radiation-safety practices, supporting timely mitigation of contamination risks and helping protect public health. However, measuring radiation is often time-consuming, rendering traditional gradient-based source-seeking methods less effective due to lower sample efficiency. This paper proposes a sample-efficient Bayesian-Optimisation source-seeking strategy that utilises a heteroscedastic Gaussian process surrogate to balance exploration and exploitation. Excessive inter-sample travel is discouraged through a movement switching cost. The strategy is shown to generate sublinear regret in the source-seeking task, while simulations demonstrate its effectiveness in localising radioactive sources. △ Less

Submitted 14 May, 2026; originally announced May 2026.

Roadmap on Attosecond Science

Authors: Rocio Borrego Varillas, Pierre Agostini, Fernando Ardana-Lamas, Cord L. Arnold, David Ayuso, Maurizio Reduzzi, Jakub Benda, Jens Biegert, Charles Bourassin-Bouchet, Thomas Brabec, Christian Brahms, Andrew C. Brown, David Busto, Jérémie Caillat, Francesca Calegari, Carlo Callegari, Stefanos Carlström, Zenghu Chang, Ming-Chang Chen, Anna G. Ciriolo, Paul Corkum, Gabriele Crippa, Rafael de Q. Garcia, Louis DiMauro, Nirit Dudovich , et al. (86 additional authors not shown)

Abstract: Twenty-five years have passed since the first experimental demonstration of attosecond pulses, marking the advent of our ability to resolve and control electron motion in real time. What began as a technological breakthrough - generating the shortest flashes ever produced - has evolved into a powerful approach for probing and steering electronic dynamics in atoms, molecules, and solids. This roadm… ▽ More Twenty-five years have passed since the first experimental demonstration of attosecond pulses, marking the advent of our ability to resolve and control electron motion in real time. What began as a technological breakthrough - generating the shortest flashes ever produced - has evolved into a powerful approach for probing and steering electronic dynamics in atoms, molecules, and solids. This roadmap, authored by leading experts in the field, surveys the recent rapid progress in the generation and characterization of attosecond pulses, emerging attosecond measurement and control techniques, and their expanding range of applications. It reviews current and future developments in attosecond light sources, including novel laser technologies, waveform synthesizers, new schemes for high-order harmonic generation, attosecond pulse generation at free-electron lasers, and structured light. Advances in attosecond measurement methodologies are also discussed, encompassing all-attosecond pump-probe spectroscopy, attosecond four-wave mixing, attosecond microscopy, spectroscopy with light transients, and attosecond interferometry. Furthermore, the roadmap addresses applications of attosecond spectroscopy to reveal electron dynamics in molecules and condensed matter systems from both theoretical and experimental perspectives, and highlights emerging directions at the interface with quantum optics and quantum entanglement. Overall, this work aims to serve as a comprehensive resource for navigating the evolving landscape of attosecond science. △ Less

Submitted 16 April, 2026; originally announced April 2026.

Programmable Dynamic Phase Control of a Quasiperiodic Optical Lattice

Authors: Andrew O. Neely, Cedric C. Wilson, Ryan Everly, Yu Yao, Raffaella Zanetti, Charles D. Brown

Abstract: The quantum dynamics of quasiperiodic systems display a rich variety of physical behaviors due to the combination of rotational symmetry that is mathematically forbidden in periodic systems, and long-range order despite the lack of translation symmetry. New experimental probes into these dynamics with a quantum simulator, consisting of ultracold atoms in an optical lattice potential, will yield ne… ▽ More The quantum dynamics of quasiperiodic systems display a rich variety of physical behaviors due to the combination of rotational symmetry that is mathematically forbidden in periodic systems, and long-range order despite the lack of translation symmetry. New experimental probes into these dynamics with a quantum simulator, consisting of ultracold atoms in an optical lattice potential, will yield new insights into the physics of quasiperiodic systems. This potential is imbued with the flexibility, tunability, and purity of the individual laser beams that constitute it, allowing for exquisite control over a rich system. Programmable dynamic control over the lattice beam phases opens up an even richer space of achievable systems via Floquet engineering. We thus describe an experimental scheme for creating a programmable, dynamic, two-dimensional (2D) quasiperiodic optical lattice with heavily suppressed phase noise. We observe suppression of phase noise for frequency components up to 5 kHz, and report phase noise suppression of over 70 dB over the DC-60 Hz frequency band. We further demonstrate a phase modulation bandwidth of 350 kHz. This scheme allows for full translational and phasonic control of the lattice, including changes to the rotational symmetry of the potential, at speeds exceeding the lattice recoil velocity, which paves a path towards direct observation and control of quantum dynamics in quasicrystals. △ Less

Submitted 30 July, 2026; v1 submitted 8 April, 2026; originally announced April 2026.

Comments: 10 pages, 7 figures

All-optical control of nonlinear emission from resonant metasurfaces

Authors: Ziwei Yang, Lei Xu, Gabriel Sanderson, Akhshay Bhadwal, Luyao Wang, Katsuya Tanaka, Muyi Yang, Mingkai Liu, Shaun Lung, Isabelle Staude, Thomas Pertsch, Carl Brown, Mohsen Rahmani, Dragomir Neshev

Abstract: Nonlinear optics underpins a broad range of photonic technologies, from classical and quantum light sources to emerging nonlinear photonic neural networks. Yet, conventional nonlinear optical devices exhibit static functionality: their transfer characteristics and emission profiles are dictated by the intrinsic nonlinear process and locked by fabrication, limiting adaptability. Here, we introduce… ▽ More Nonlinear optics underpins a broad range of photonic technologies, from classical and quantum light sources to emerging nonlinear photonic neural networks. Yet, conventional nonlinear optical devices exhibit static functionality: their transfer characteristics and emission profiles are dictated by the intrinsic nonlinear process and locked by fabrication, limiting adaptability. Here, we introduce an ultra-thin metasurface platform that enables dynamic reconfiguration of nonlinear functionality in a contact-less fashion. By leveraging all-optical control of the optical torque exerted on liquid crystal molecules infiltrating a resonant metasurface, we achieve tunable polynomial nonlinear transfer functions based on third-harmonic generation process. This mechanism further allows real-time modulation of nonlinear weighting across different diffraction orders, revealing a previously unexplored interplay between mode structure and nonlinear emission. Our approach opens up a pathway toward field-programmable nonlinear photonic systems, offering unprecedented flexibility for reconfigurable nonlinear signal processing and adaptive photonic computing. △ Less

Submitted 4 April, 2026; originally announced April 2026.

Comments: 29 pages, 6 figures, article

ICHOR: A Robust Representation Learning Approach for ASL CBF Maps with Self-Supervised Masked Autoencoders

Authors: Xavier Beltran-Urbano, Yiran Li, Xinglin Zeng, Katie R. Jobson, Manuel Taso, Christopher A. Brown, David A. Wolk, Corey T. McMillan, Ilya M. Nashrallah, Paul A. Yushkevich, Ze Wang, John A. Detre, Sudipto Dolui

Abstract: Arterial spin labeling (ASL) perfusion MRI allows direct quantification of regional cerebral blood flow (CBF) without exogenous contrast, enabling noninvasive measurements that can be repeated without constraints imposed by contrast injection. ASL is increasingly acquired in research studies and clinical MRI protocols. Building on successes in structural imaging, recent efforts have implemented de… ▽ More Arterial spin labeling (ASL) perfusion MRI allows direct quantification of regional cerebral blood flow (CBF) without exogenous contrast, enabling noninvasive measurements that can be repeated without constraints imposed by contrast injection. ASL is increasingly acquired in research studies and clinical MRI protocols. Building on successes in structural imaging, recent efforts have implemented deep learning based methods to improve image quality, enable automated quality control, and derive robust quantitative and predictive biomarkers with ASL derived CBF. However, progress has been limited by variable image quality, substantial inter-site, vendor and protocol differences, and limited availability of labeled datasets needed to train models that generalize across cohorts. To address these challenges, we introduce ICHOR, a self supervised pre-training approach for ASL CBF maps that learns transferable representations using 3D masked autoencoders. ICHOR is pretrained via masked image modeling using a Vision Transformer backbone and can be used as a general-purpose encoder for downstream ASL tasks. For pre-training, we curated one of the largest ASL datasets to date, comprising 11,405 ASL CBF scans from 14 studies spanning multiple sites and acquisition protocols. We evaluated the pre-trained ICHOR encoder on three downstream diagnostic classification tasks and one ASL CBF map quality prediction regression task. Across all evaluations, ICHOR outperformed existing neuroimaging self-supervised pre-training methods adapted to ASL. Pre-trained weights and code will be made publicly available. △ Less

Submitted 5 March, 2026; originally announced March 2026.

Multiscale geometric analysis of dynamic wettability on complex, fractal-like, anisotropic surfaces

Authors: Katarzyna Peta, Krzysztof J. Kubiak, Christopher A. Brown

Abstract: This study introduces novel insights into the development of procedures for identifying the most relevant scales for observing the interactions of dynamic wettability and surface complexities. The experimental procedures presented for measuring dynamic contact angle hysteresis in multiscale correlation with the geometric characteristics of anisotropic surfaces contribute to a new perspective on me… ▽ More This study introduces novel insights into the development of procedures for identifying the most relevant scales for observing the interactions of dynamic wettability and surface complexities. The experimental procedures presented for measuring dynamic contact angle hysteresis in multiscale correlation with the geometric characteristics of anisotropic surfaces contribute to a new perspective on measurement practice. In this study, microtexturing with a pyramidal structured abrasive belt is applied for precisely forming area- and length-scale anisotropic surface complexities, and consequently, topographically dependent functional features. The significant role of anisotropic topographies in modeling dynamic wettability behavior is highlighted through multiscale measurement-based analysis. These studies verify the relationship between dynamic wettability and the finest surface microgeometry (microroughness) and also the coarsest texture components (waviness). The size of topographic features, ranging from microroughness to waviness, significantly influences droplet pinning and liquid entrapment. Furthermore, the influence of material hydrophilicity and hydrophobicity on the calculated multiscale relationships is assessed. The results indicated specific scales that best correlate with dynamic wettability, with length- and area-scale complexities of 6.9 um and 28 um2, respectively. A novel measurement-based approach to scale-dependent surface-functionality interactions offers new insights for designing dynamic wettability on anisotropic surfaces. △ Less

Submitted 14 January, 2026; v1 submitted 11 January, 2026; originally announced January 2026.

Comments: Accepted manuscript

Journal ref: Measurement (Elsevier), Volume 264, 10 March 2026, 120328

The Great January Comet of 1910 (C/1910 A1): A Key Opportunity Missed by New Zealand Astronomers

Authors: John Drummond, Wayne Orchiston, Carolyn Brown, Jonathan Horner

Abstract: C/1910 A1 was one of the Great Comets of the twentieth century. Although it was widely observed from the Northern Hemisphere, it was first discovered by observers south of the Equator. The comet arrived just months before the widely anticipated apparition of Comet 1P/Halley and was significantly more spectacular. As a result, the two comets were confused, and many who, in later years, talked about… ▽ More C/1910 A1 was one of the Great Comets of the twentieth century. Although it was widely observed from the Northern Hemisphere, it was first discovered by observers south of the Equator. The comet arrived just months before the widely anticipated apparition of Comet 1P/Halley and was significantly more spectacular. As a result, the two comets were confused, and many who, in later years, talked about how prominent Comet 1P/Halley was in 1910 were often remembering C/1910 A1. In this paper, we present the results of a detailed search through historical records and media publications in Aotearoa / New Zealand, to investigate how extensively C/1910 A1 was observed from New Zealand. We compare our results with observations reported for Comet 1P/Halley later in 1910, finding that surprisingly few observations of C/1910 A1 were made by New Zealand observers. We discuss cases where the comet was misidentified as being an early sighting of 1P/Halley and compare the observations made in New Zealand with international observations/records/accounts. We find that, although the Great January Comet of 1910 was observed from New Zealand, it was witnessed by few compared to other parts of the world, meaning that the apparition of C/1910 A1 was something of a missed opportunity for New Zealand astronomers. △ Less

Submitted 16 November, 2025; originally announced November 2025.

Comments: 22 pages; published in the Journal of Astronomical History and Heritage

Journal ref: Journal of Astronomical History and Heritage, 28(3), 689-710, 2025

Development and Flight Trial of a UAV-based Gamma Ray and Neutron Detection System for Large-Area Radioactivity Mapping and Source Activity Estimation

Authors: Lysander Miller, Airlie Chapman, James Kennedy, Richard Hebden, Jeremy M. C. Brown

Abstract: Advances in scintillation crystal and Silicon PhotoMultiplier (SiPM) technologies have enabled the development of compact, lightweight, and low-power radiation detectors that are suitable for integration with Unmanned Aerial Vehicles (UAVs). This integration enables efficient and cost-effective large-area radiation monitoring while minimising occupational exposure. In this work, a SiPM-based NaIL… ▽ More Advances in scintillation crystal and Silicon PhotoMultiplier (SiPM) technologies have enabled the development of compact, lightweight, and low-power radiation detectors that are suitable for integration with Unmanned Aerial Vehicles (UAVs). This integration enables efficient and cost-effective large-area radiation monitoring while minimising occupational exposure. In this work, a SiPM-based NaIL scintillation detection payload was developed, characterised, and mounted on a multirotor UAV for gamma ray and neutron source localisation and activity estimation applications. To support these capabilities, an analytic radionuclide detection efficiency model was developed and used to estimate radioactivity on the ground from aerial energy spectrum measurements. The analytic expression for the detection efficiency incorporated physical phenomena, including the branching ratio, detector solid angle, air attenuation, and intrinsic peak efficiency, leading to agreement within 10% of experimental radionuclide detection efficiencies. The UAV-based radiation detection system was physically validated through a controlled indoor live radioactive source demonstration at 1.5 m, 3 m, and 4.5 m flight heights. Using the developed ground-level radioactivity estimation method, Cs-137 and Co-60 sources were successfully localised within 0.5 m, and their activities were estimated with errors on the order of 10% or less. △ Less

Submitted 28 October, 2025; originally announced October 2025.

Comments: 8 pages, 9 figures

Advancing the CMS Level-1 Trigger: Jet Tagging with DeepSets at the HL-LHC

Authors: Stella Schaefer, Christopher Brown, Duc Hoang, Sioni Summers, Sebastian Wuchterl

Abstract: At the High Luminosity LHC, selecting important physics processes such as (di-) Higgs production will be a high priority. The Phase-2 Upgrade of the CMS Level-1 Trigger will reconstruct particle candidates and use pileup mitigation for the 200 simultaneous proton-proton interactions. A fast cone algorithm will reconstruct jets from these particles, providing access to jet constituents for the firs… ▽ More At the High Luminosity LHC, selecting important physics processes such as (di-) Higgs production will be a high priority. The Phase-2 Upgrade of the CMS Level-1 Trigger will reconstruct particle candidates and use pileup mitigation for the 200 simultaneous proton-proton interactions. A fast cone algorithm will reconstruct jets from these particles, providing access to jet constituents for the first time. We introduce a new multi-class jet tagger with a small, quantized DeepSets neural network. The tagger, trained on a mix of simulated CMS events, predicts various hadronic and leptonic classes. We present the tagger, its performance, and its improvements for triggering on (di-) Higgs events. △ Less

Submitted 20 November, 2025; v1 submitted 29 September, 2025; originally announced September 2025.

Modelling the impact of synovial fluid elasticity on tangential stress

Authors: Eamonn A. Gaffney, Cameron P. Brown, Jonathan P. Whiteley

Abstract: The rheological properties of synovial fluid have been observed to substantially impact its lubricating behaviour. While numerous studies have illustrated the importance of its shear-dependent viscosity, the impact of synovial fluid elasticity for oscillatory joint motion is far less characterised. Hence we consider how elasticity impacts the tangential stress, and thus friction, exerted on confin… ▽ More The rheological properties of synovial fluid have been observed to substantially impact its lubricating behaviour. While numerous studies have illustrated the importance of its shear-dependent viscosity, the impact of synovial fluid elasticity for oscillatory joint motion is far less characterised. Hence we consider how elasticity impacts the tangential stress, and thus friction, exerted on confining surfaces in rheological models of synovial fluid on the length and time scales of oscillatory joint motion, though in a simplified setting rather than considering the full complexity of a joint. Minor changes in the elastic constitutive equation from a canonical upper convected Oldroyd-B model lead to fundamentally different scalings and predictions for tangential stress compared to either a Newtonian fluid and an Oldroyd-B fluid. In particular, polymer elasticity within physiological fluids is predicted to have a profound effect on friction both within the oscillating joint and more generally, in turn suggesting further examination of synovial fluid elasticity in experimental and modelling studies. △ Less

Submitted 22 August, 2025; originally announced August 2025.

Comments: 32 pages, 6 figures

Blackbody radiation Zeeman shift in Rydberg atoms

Authors: K. Beloy, B. D. Hunt, R. C. Brown, T. Bothwell, Y. S. Hassan, J. L. Siegel, T. Grogan, A. D. Ludlow

Abstract: We consider the Zeeman shift in Rydberg atoms induced by room-temperature blackbody radiation (BBR). BBR shifts to the Rydberg levels are dominated by the familiar BBR Stark shift. However, the BBR Stark shift and the BBR Zeeman shift exhibit different behaviors with respect to the principal quantum number of the Rydberg electron. Namely, the BBR Stark shift asymptotically approaches a constant va… ▽ More We consider the Zeeman shift in Rydberg atoms induced by room-temperature blackbody radiation (BBR). BBR shifts to the Rydberg levels are dominated by the familiar BBR Stark shift. However, the BBR Stark shift and the BBR Zeeman shift exhibit different behaviors with respect to the principal quantum number of the Rydberg electron. Namely, the BBR Stark shift asymptotically approaches a constant value given by a universal expression, whereas the BBR Zeeman shift grows steeply with principal quantum number due to the diamagnetic contribution. We show that for transitions between Rydberg states, where only the differential shift between levels is of concern, the BBR Zeeman shift can surpass the BBR Stark shift. We exemplify this in the context of a proposed experiment targeting a precise determination of the Rydberg constant. △ Less

Submitted 1 July, 2025; originally announced July 2025.

Comments: 7 pages

Journal ref: Phys. Rev. A 111, 062819 (2025)

Cryogenic Optical Lattice Clock with $1.7\times 10^{-20}$ Blackbody Radiation Stark Uncertainty

Authors: Youssef S. Hassan, Kyle Beloy, Jacob L. Siegel, Takumi Kobayashi, Eric Swiler, Tanner Grogan, Roger C. Brown, Tristan Rojo, Tobias Bothwell, Benjamin D. Hunt, Adam Halaoui, Andrew D. Ludlow

Abstract: Controlling the Stark perturbation from ambient thermal radiation is key to advancing the performance of many atomic frequency standards, including state-of-the-art optical lattice clocks (OLCs). We demonstrate a cryogenic OLC that utilizes a dynamically actuated radiation shield to control the perturbation at $1.7\times10^{-20}$ fractional frequency, a factor of $\sim$40 beyond the best OLC to da… ▽ More Controlling the Stark perturbation from ambient thermal radiation is key to advancing the performance of many atomic frequency standards, including state-of-the-art optical lattice clocks (OLCs). We demonstrate a cryogenic OLC that utilizes a dynamically actuated radiation shield to control the perturbation at $1.7\times10^{-20}$ fractional frequency, a factor of $\sim$40 beyond the best OLC to date. Our shield furnishes the atoms with a near-ideal cryogenic blackbody radiation (BBR) environment by rejecting external thermal radiation at the part-per-million level during clock spectroscopy, overcoming a key limitation with previous cryogenic BBR control solutions in OLCs. While the lowest BBR shift uncertainty is realized with cryogenic operation, we further exploit the radiation control that the shield offers over a wide range of temperatures to directly measure and verify the leading BBR Stark dynamic correction coefficient for ytterbium. This independent measurement reduces the literature-combined uncertainty of this coefficient by 30%, thus benefiting state-of-the-art Yb OLCs operated at room temperature. We verify the static BBR coefficient for Yb at the low $10^{-18}$ level. △ Less

Submitted 6 June, 2025; v1 submitted 5 June, 2025; originally announced June 2025.

Comments: 21 pages (7 main + 14 SM), 6 figures (3 main + 3 SM), 1 table, submitted

Neutron Beam Shaping by Ghost Projection

Authors: Andrew M. Kingston, Alaleh Aminzadeh, Lindon Roberts, Jeremy M. C. Brown, Filomena Salvemini, Joseph J. Bevitt, Ulf Garbe, David M. Paganin

Abstract: We present a method to shape a neutron beam and project any specified target image using a single universal patterned mask that is transversely displaced. The method relies on ``ghost projection'', which is a reversed form of classical ghost imaging. A set of sub-mask regions that combine to construct the required beam shape is computed; illumination of each region with the determined exposure tim… ▽ More We present a method to shape a neutron beam and project any specified target image using a single universal patterned mask that is transversely displaced. The method relies on ``ghost projection'', which is a reversed form of classical ghost imaging. A set of sub-mask regions that combine to construct the required beam shape is computed; illumination of each region with the determined exposure time projects the shaped beam. We demonstrate this method experimentally, using the Dingo neutron imaging beamline at the OPAL nuclear research reactor (Australia). The ability to shape a neutron beam ``on demand'' allows selective dose delivery away from sensitive areas of samples, such as in cultural heritage artifacts. It also benefits irradiation techniques, e.g., in testing resilience of electronic components for space and defense technologies or neutron therapies. △ Less

Submitted 10 April, 2025; v1 submitted 26 February, 2025; originally announced February 2025.

Phase evolution of strong-field ionization

Authors: Lynda R Hutcheson, Maximilian Hartmann, Gergana D Borisova, Paul Birk, Shuyuan Hu, Christian Ott, Thomas Pfeifer, Hugo W van der Hart, Andrew C Brown

Abstract: We investigate the time-dependent evolution of the dipole phase shift induced by strong-field ionization (SFI) using attosecond transient absorption spectroscopy (ATAS) for time-delays where the pump-probe pulses overlap. We study measured and calculated time-dependent ATA spectra of the ionic 4d-5p transition in xenon, and present the time-dependent line shape parameters in the complex plane. We… ▽ More We investigate the time-dependent evolution of the dipole phase shift induced by strong-field ionization (SFI) using attosecond transient absorption spectroscopy (ATAS) for time-delays where the pump-probe pulses overlap. We study measured and calculated time-dependent ATA spectra of the ionic 4d-5p transition in xenon, and present the time-dependent line shape parameters in the complex plane. We attribute the complex, attosecond-scale dynamics to the contribution of three distinct processes: accumulation of ionization, transient population, and reversible population of excited states arising from polarization of the ground state. △ Less

Submitted 26 February, 2025; originally announced February 2025.

Comments: 6 pages, 6 figures. All data in the manuscript and the minimal model can be found in the GitHub repository, see https://github.com/lhutcheson/dipole_response.git

dZiner: Rational Inverse Design of Materials with AI Agents

Authors: Mehrad Ansari, Jeffrey Watchorn, Carla E. Brown, Joseph S. Brown

Abstract: Recent breakthroughs in machine learning and artificial intelligence, fueled by scientific data, are revolutionizing the discovery of new materials. Despite the wealth of existing scientific literature, the availability of both structured experimental data and chemical domain knowledge that can be easily integrated into data-driven workflows is limited. The motivation to integrate this information… ▽ More Recent breakthroughs in machine learning and artificial intelligence, fueled by scientific data, are revolutionizing the discovery of new materials. Despite the wealth of existing scientific literature, the availability of both structured experimental data and chemical domain knowledge that can be easily integrated into data-driven workflows is limited. The motivation to integrate this information, as well as additional context from first-principle calculations and physics-informed deep learning surrogate models, is to enable efficient exploration of the relevant chemical space and to predict structure-property relationships of new materials a priori. Ultimately, such a framework could replicate the expertise of human subject-matter experts. In this work, we present dZiner, a chemist AI agent, powered by large language models (LLMs), that discovers new compounds with desired properties via inverse design (property-to-structure). In specific, the agent leverages domain-specific insights from foundational scientific literature to propose new materials with enhanced chemical properties, iteratively evaluating them using relevant surrogate models in a rational design process, while accounting for design constraints. The model supports both closed-loop and human-in-the-loop feedback cycles, enabling human-AI collaboration in molecular design with real-time property inference, and uncertainty and chemical feasibility assessment. We demonstrate the flexibility of this agent by applying it to various materials target properties, including surfactants, ligand and drug candidates, and metal-organic frameworks. Our approach holds promise to both accelerate the discovery of new materials and enable the targeted design of materials with desired functionalities. The methodology is available as an open-source software on https://github.com/mehradans92/dZiner. △ Less

Submitted 4 October, 2024; originally announced October 2024.

Lattice Light Shift Evaluations In a Dual-Ensemble Yb Optical Lattice Clock

Authors: Tobias Bothwell, Benjamin D. Hunt, Jacob L. Siegel, Youssef S. Hassan, Tanner Grogan, Takumi Kobayashi, Kurt Gibble, Sergey G. Porsev, Marianna S. Safronova, Roger C. Brown, Kyle Beloy, Andrew D. Ludlow

Abstract: In state-of-the-art optical lattice clocks, beyond-electric-dipole polarizability terms lead to a break-down of magic wavelength trapping. In this Letter, we report a novel approach to evaluate lattice light shifts, specifically addressing recent discrepancies in the atomic multipolarizability term between experimental techniques and theoretical calculations. We combine imaging and multi-ensemble… ▽ More In state-of-the-art optical lattice clocks, beyond-electric-dipole polarizability terms lead to a break-down of magic wavelength trapping. In this Letter, we report a novel approach to evaluate lattice light shifts, specifically addressing recent discrepancies in the atomic multipolarizability term between experimental techniques and theoretical calculations. We combine imaging and multi-ensemble techniques to evaluate lattice light shift atomic coefficients, leveraging comparisons in a dual-ensemble lattice clock to rapidly evaluate differential frequency shifts. Further, we demonstrate application of a running wave field to probe both the multipolarizability and hyperpolarizability coefficients, establishing a new technique for future lattice light shift evaluations. △ Less

Submitted 16 September, 2024; originally announced September 2024.

Comments: 17 pages, 6 figures

Clock-line-mediated Sisyphus Cooling

Authors: Chun-Chia Chen, Jacob L. Siegel, Benjamin D. Hunt, Tanner Grogan, Youssef S. Hassan, Kyle Beloy, Kurt Gibble, Roger C. Brown, Andrew D. Ludlow

Abstract: We demonstrate sub-recoil Sisyphus cooling using the long-lived $^{3}\mathrm{P}_{0}$ clock state in alkaline-earth-like ytterbium. A 1388 nm optical standing wave nearly resonant with the $^{3}\textrm{P}_{0}$$\,\rightarrow$$\,^{3}\textrm{D}_{1}$ transition creates a spatially periodic light shift of the $^{3}\textrm{P}_{0}$ clock state. Following excitation on the ultranarrow clock transition, we… ▽ More We demonstrate sub-recoil Sisyphus cooling using the long-lived $^{3}\mathrm{P}_{0}$ clock state in alkaline-earth-like ytterbium. A 1388 nm optical standing wave nearly resonant with the $^{3}\textrm{P}_{0}$$\,\rightarrow$$\,^{3}\textrm{D}_{1}$ transition creates a spatially periodic light shift of the $^{3}\textrm{P}_{0}$ clock state. Following excitation on the ultranarrow clock transition, we observe Sisyphus cooling in this potential, as the light shift is correlated with excitation to $^{3}\textrm{D}_{1}$ and subsequent spontaneous decay to the $^{1}\textrm{S}_{0}$ ground state. We observe that cooling enhances the loading efficiency of atoms into a 759 nm magic-wavelength one-dimensional (1D) optical lattice, as compared to standard Doppler cooling on the $^{1}\textrm{S}_{0}$$\,\rightarrow\,$$^{3}\textrm{P}_{1}$ transition. Sisyphus cooling yields temperatures below 200 nK in the weakly confined, transverse dimensions of the 1D optical lattice. These lower temperatures improve optical lattice clocks by facilitating the use of shallow lattices with reduced light shifts, while retaining large atom numbers to reduce the quantum projection noise. This Sisyphus cooling can be pulsed or continuous and is applicable to a range of quantum metrology applications. △ Less

Submitted 19 June, 2024; originally announced June 2024.

Comments: 8 pages, 6 figures

Journal ref: Phys. Rev. Lett. 133, 053401 (2024)

Quantum-Enhanced Neural Exchange-Correlation Functionals

Authors: Igor O. Sokolov, Gert-Jan Both, Art D. Bochevarov, Pavel A. Dub, Daniel S. Levine, Christopher T. Brown, Shaheen Acheche, Panagiotis Kl. Barkoutsos, Vincent E. Elfving

Abstract: Kohn-Sham Density Functional Theory (KS-DFT) provides the exact ground state energy and electron density of a molecule, contingent on the as-yet-unknown universal exchange-correlation (XC) functional. Recent research has demonstrated that neural networks can efficiently learn to represent approximations to that functional, offering accurate generalizations to molecules not present during the train… ▽ More Kohn-Sham Density Functional Theory (KS-DFT) provides the exact ground state energy and electron density of a molecule, contingent on the as-yet-unknown universal exchange-correlation (XC) functional. Recent research has demonstrated that neural networks can efficiently learn to represent approximations to that functional, offering accurate generalizations to molecules not present during the training process. With the latest advancements in quantum-enhanced machine learning (ML), evidence is growing that Quantum Neural Network (QNN) models may offer advantages in ML applications. In this work, we explore the use of QNNs for representing XC functionals, enhancing and comparing them to classical ML techniques. We present QNNs based on differentiable quantum circuits (DQCs) as quantum (hybrid) models for XC in KS-DFT, implemented across various architectures. We assess their performance on 1D and 3D systems. To that end, we expand existing differentiable KS-DFT frameworks and propose strategies for efficient training of such functionals, highlighting the importance of fractional orbital occupation for accurate results. Our best QNN-based XC functional yields energy profiles of the H$_2$ and planar H$_4$ molecules that deviate by no more than 1 mHa from the reference DMRG and FCI/6-31G results, respectively. Moreover, they reach chemical precision on a system, H$_2$H$_2$, not present in the training dataset, using only a few variational parameters. This work lays the foundation for the integration of quantum models in KS-DFT, thereby opening new avenues for expressing XC functionals in a differentiable way and facilitating computations of various properties. △ Less

Submitted 26 January, 2026; v1 submitted 22 April, 2024; originally announced April 2024.

Journal ref: Phys. Rev. A 113 (2026) 012427

Material Properties of Popular Radiation Detection Scintillator Crystals for Optical Physics Transport Modelling in Geant4

Authors: Lysander Miller, Airlie Chapman, Katie Auchettl, Jeremy M. C. Brown

Abstract: Radiation detection is vital for space, medical imaging, homeland security, and environmental monitoring applications. In the past, the Monte Carlo radiation transport toolkit, Geant4, has been employed to enable the effective development of emerging technologies in these fields. Radiation detectors utilising scintillator crystals have benefited from Geant4; however, Geant4 optical physics paramet… ▽ More Radiation detection is vital for space, medical imaging, homeland security, and environmental monitoring applications. In the past, the Monte Carlo radiation transport toolkit, Geant4, has been employed to enable the effective development of emerging technologies in these fields. Radiation detectors utilising scintillator crystals have benefited from Geant4; however, Geant4 optical physics parameters for scintillator crystal modelling are sparse. This work outlines scintillator properties for GAGG:Ce, CLLBC:Ce, BGO, NaI:Tl, and CsI:Tl. These properties were implemented in a detailed SiPM-based single-volume scintillation detector simulation platform developed in this work. It was validated by its comparison to experimental measurements. For all five scintillation materials, the platform successfully predicted the spectral features for selected gamma ray emitting isotopes with energies between 30 keV to 2 MeV. The full width half maximum (FWHM) and normalised cross-correlation coefficient (NCCC) between simulated and experimental energy spectra were also compared. The majority of simulated FWHM values reproduced the experimental results within a 2% difference, and the majority of NCCC values demonstrated agreement between the simulated and experimental energy spectra. Discrepancies in these figures of merit were attributed to detector signal processing electronics modelling and geometry approximations within the detector and surrounding experimental environment. △ Less

Submitted 11 October, 2024; v1 submitted 5 March, 2024; originally announced March 2024.

Transverse Emittance Reduction in Muon Beams by Ionization Cooling

Authors: The MICE Collaboration, M. Bogomilov, R. Tsenov, G. Vankova-Kirilova, Y. P. Song, J. Y. Tang, Z. H. Li, R. Bertoni, M. Bonesini, F. Chignoli, R. Mazza, A. de Bari, D. Orestano, L. Tortora, Y. Kuno, H. Sakamoto, A. Sato, S. Ishimoto, M. Chung, C. K. Sung, F. Filthaut, M. Fedorov, D. Jokovic, D. Maletic, M. Savic , et al. (112 additional authors not shown)

Abstract: Accelerated muon beams have been considered for next-generation studies of high-energy lepton-antilepton collisions and neutrino oscillations. However, high-brightness muon beams have not yet been produced. The main challenge for muon acceleration and storage stems from the large phase-space volume occupied by the beam, derived from the muon production mechanism through the decay of pions from pro… ▽ More Accelerated muon beams have been considered for next-generation studies of high-energy lepton-antilepton collisions and neutrino oscillations. However, high-brightness muon beams have not yet been produced. The main challenge for muon acceleration and storage stems from the large phase-space volume occupied by the beam, derived from the muon production mechanism through the decay of pions from proton collisions. Ionization cooling is the technique proposed to decrease the muon beam phase-space volume. Here we demonstrate a clear signal of ionization cooling through the observation of transverse emittance reduction in beams that traverse lithium hydride or liquid hydrogen absorbers in the Muon Ionization Cooling Experiment (MICE). The measurement is well reproduced by the simulation of the experiment and the theoretical model. The results shown here represent a substantial advance towards the realization of muon-based facilities that could operate at the energy and intensity frontiers. △ Less

Submitted 13 October, 2023; v1 submitted 9 October, 2023; originally announced October 2023.

Comments: 23 pages and 5 figures

Report number: STFC-P-2023-004

Estimation of the number of single-photon emitters for multiple fluorophores with the same spectral signature

Authors: Wenchao Li, Shuo Li, Timothy C. Brown, Qiang Sun, Xuezhi Wang, Vladislav V. Yakovlev, Allison Kealy, Bill Moran, Andrew D. Greentree

Abstract: Fluorescence microscopy is of vital importance for understanding biological function. However most fluorescence experiments are only qualitative inasmuch as the absolute number of fluorescent particles can often not be determined. Additionally, conventional approaches to measuring fluorescence intensity cannot distinguish between two or more fluorophores that are excited and emit in the same spect… ▽ More Fluorescence microscopy is of vital importance for understanding biological function. However most fluorescence experiments are only qualitative inasmuch as the absolute number of fluorescent particles can often not be determined. Additionally, conventional approaches to measuring fluorescence intensity cannot distinguish between two or more fluorophores that are excited and emit in the same spectral window, as only the total intensity in a spectral window can be obtained. Here we show that, by using photon number resolving experiments, we are able to determine the number of emitters and their probability of emission for a number of different species, all with the same measured spectral signature. We illustrate our ideas by showing the determination of the number of emitters per species and the probability of photon collection from that species, for one, two, and three otherwise unresolvable fluorophores. The convolution Binomial model is presented to model the counted photons emitted by multiple species. And then the Expectation-Maximization (EM) algorithm is used to match the measured photon counts to the expected convolution Binomial distribution function. In applying the EM algorithm, to leverage the problem of being trapped in a sub-optimal solution, the moment method is introduced in finding the initial guess of the EM algorithm. Additionally, the associated Cramér-Rao lower bound is derived and compared with the simulation results. △ Less

Submitted 12 February, 2024; v1 submitted 8 June, 2023; originally announced June 2023.

The LHCb upgrade I

Authors: LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, C. Achard, T. Ackernley, B. Adeva, M. Adinolfi, P. Adlarson, H. Afsharnia, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, A. Alfonso Albero, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato , et al. (1298 additional authors not shown)

Abstract: The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their select… ▽ More The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software. △ Less

Submitted 10 September, 2024; v1 submitted 17 May, 2023; originally announced May 2023.

Comments: All figures and tables, along with any supplementary material and additional information, are available at http://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-DP-2022-002.html (LHCb public pages)

Report number: LHCb-DP-2022-002

Journal ref: JINST 19 (2024) P05065

Modelling the Response of CLLBC(Ce) and TLYC(Ce) SiPM-Based Radiation Detectors in Mixed Radiation Fields with Geant4

Authors: Jeremy M. C. Brown, Lachlan Chartier, David Boardman, John Barnes, Alison Flynn

Abstract: CLLBC(Ce) and TLYC(Ce) are novel scintillation materials capable of measuring mixed gamma ray and neutron radiation fields that have gained significant interest in the areas of space and nuclear safety/security science. To date Geant4, the world's most popular Monte Carlo radiation modelling toolkit, has yet to be effectively used to simulate the full response of these materials when coupled to ne… ▽ More CLLBC(Ce) and TLYC(Ce) are novel scintillation materials capable of measuring mixed gamma ray and neutron radiation fields that have gained significant interest in the areas of space and nuclear safety/security science. To date Geant4, the world's most popular Monte Carlo radiation modelling toolkit, has yet to be effectively used to simulate the full response of these materials when coupled to near ultra-violet Silicon PhotoMultipliers (SiPMs). In this work an experimentally validated Geant4 application has been developed with optimised material composition, optical data tables, and physics transport settings that is able to accurately simulate the response of CLLBC(Ce) and TLYC(Ce) SiPM-based radiation detectors under both gamma ray and neutron irradiation. Experimental benchmarking for five different radioactive sources (Co-60, Cs-137, Eu-152, Am-241, and Cf-252) illustrated that this developed Geant4 application was able to reproduce the position and structure of all major spectral features (full energy gamma ray photo-/neutron capture peaks, X-ray escape photopeaks, Compton edge, Compton backscatter peaks, and Compton plateau) to high level of accuracy. △ Less

Submitted 16 March, 2023; originally announced March 2023.

A Geant4 Based Simulation Platform of the HollandPTC R&D Proton Beamline for Radiobiological Studies

Authors: C. F. Groenendijk, M. Rovituso, D. Lathouwers, J. M. C. Brown

Abstract: A Geant4 based simulation platform of the Holland Proton Therapy Centre (HollandPTC, Netherlands) R&D beamline (G4HPTC-R&D) was developed to enable the planning, optimisation and advanced dosimetry for radiobiological studies. It implemented a six parameter non-symmetrical Gaussian pencil beam surrogate model to simulate the R&D beamline in both a pencil beam and passively scattered field configur… ▽ More A Geant4 based simulation platform of the Holland Proton Therapy Centre (HollandPTC, Netherlands) R&D beamline (G4HPTC-R&D) was developed to enable the planning, optimisation and advanced dosimetry for radiobiological studies. It implemented a six parameter non-symmetrical Gaussian pencil beam surrogate model to simulate the R&D beamline in both a pencil beam and passively scattered field configuration. Three different experimental proton datasets (70 MeV, 150 MeV, and 240 MeV) of the pencil beam envelope evolution in free air and depth-dose profiles in water were used to develop a set of individual parameter surrogate functions to enable the modelling of the non-symmetrical Gaussian pencil beam properties with only the ProBeam isochronous cyclotron mean extraction proton energy as input. This refined beam model was then benchmarked with respect to three independent experimental datasets of the R&D beamline operating in both a pencil beam configuration at 120 and 200 MeV, and passively scattered field configuration at 150 MeV. It was shown that the G4HPTC-R&D simulation platform can reproduce the pencil beam envelope evolution in free air and depth-dose profiles to within an accuracy on the order of $\pm$5% for all tested energies, and that it was able to reproduce the 150 MeV passively scattered field to the specifications need for clinical and radiobiological applications. △ Less

Submitted 30 May, 2023; v1 submitted 20 February, 2023; originally announced February 2023.

Characterisation of the HollandPTC R&D proton beamline for physics and radiobiology studies

Authors: M. Rovituso, C. F. Groenendijk, E. van der Wal, W. van Burik, A. Ibrahimi, H. Rituerto Prieto, J. M. C. Brown, U. Weber, Y. Simeonov, M. Fontana, D. Lathouwers, M. van Vulpen, M. Hoogeman

Abstract: HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D consortium conducts scientific research into the added value and improvements of proton therapy. To this end, HollandPTC created clinical and pre-clinical research f… ▽ More HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D consortium conducts scientific research into the added value and improvements of proton therapy. To this end, HollandPTC created clinical and pre-clinical research facilities including a versatile R&D proton beamline for various types of biologically and technologically oriented research. In this work, we present the characterization of the R&D proton beam line of HollandPTC. Its pencil beam mimics the one used for clinical IMPT, with energy ranging from 70 up to 240 MeV, which has been characterized in terms of shape, size, and intensity. For experiments that need a uniform field in depth and lateral directions, a dual ring passive scattering system has been designed, built, and characterized. With this system, field sizes between 2x2 cm2 and 20x20 cm2 with 98% uniformity are produced with dose rates ranging from 0.5 Gy/min up to 9 Gy/min. The unique and customized support of the dual ring system allows switching between a pencil beam and a large field in a very simple and fast way, making the HollandPTC R&D proton beam able to support a wide range of different applications. △ Less

Submitted 20 February, 2023; originally announced February 2023.

Isolation and Phase-Space Energization Analysis of the Instabilities in Collisionless Shocks

Authors: Collin R. Brown, James Juno, Gregory G. Howes, Colby C. Haggerty, Sage Constantinou

Abstract: We analyze the generation of kinetic instabilities and their effect on the energization of ions in non-relativistic, oblique collisionless shocks using a 3D-3V simulation by $\texttt{dHybridR}$, a hybrid particle-in-cell code. At sufficiently high Mach number, quasi-perpendicular and oblique shocks can experience rippling of the shock surface caused by kinetic instabilities arising from free energ… ▽ More We analyze the generation of kinetic instabilities and their effect on the energization of ions in non-relativistic, oblique collisionless shocks using a 3D-3V simulation by $\texttt{dHybridR}$, a hybrid particle-in-cell code. At sufficiently high Mach number, quasi-perpendicular and oblique shocks can experience rippling of the shock surface caused by kinetic instabilities arising from free energy in the ion velocity distribution due to the combination of the incoming ion beam and the population of ions reflected at the shock front. To understand the role of the ripple on particle energization, we devise the new instability isolation method to identify the unstable modes underlying the ripple and interpret the results in terms of the governing kinetic instability. We generate velocity-space signatures using the field-particle correlation technique to look at energy transfer in phase space from the isolated instability driving the shock ripple, providing a viewpoint on the different dynamics of distinct populations of ions in phase space. We generate velocity-space signatures of the energy transfer in phase space of the isolated instability driving the shock ripple using the field-particle correlation technique. Together, the field-particle correlation technique and our new instability isolation method provide a unique viewpoint on the different dynamics of distinct populations of ions in phase space and allow us to completely characterize the energetics of the collisionless shock under investigation. △ Less

Submitted 14 June, 2023; v1 submitted 28 November, 2022; originally announced November 2022.

Comments: 32 pages, 14 figures, accepted by the Journal of Plasma Physics

Phase Space Energization of Ions in Oblique Shocks

Authors: James Juno, Collin R. Brown, Gregory G. Howes, Colby C. Haggerty, Jason M. TenBarge, Lynn B. Wilson III, Damiano Caprioli, Kristopher G. Klein

Abstract: Examining energization of kinetic plasmas in phase space is a growing topic of interest, owing to the wealth of data in phase space compared to traditional bulk energization diagnostics. Via the field-particle correlation (FPC) technique and using multiple means of numerically integrating the plasma kinetic equation, we have studied the energization of ions in phase space within oblique collisionl… ▽ More Examining energization of kinetic plasmas in phase space is a growing topic of interest, owing to the wealth of data in phase space compared to traditional bulk energization diagnostics. Via the field-particle correlation (FPC) technique and using multiple means of numerically integrating the plasma kinetic equation, we have studied the energization of ions in phase space within oblique collisionless shocks. The perspective afforded to us with this analysis in phase space allows us to characterize distinct populations of energized ions. In particular, we focus on ions which reflect multiple times off the shock front through shock-drift acceleration, and how to distinguish these different reflected populations in phase space using the FPC technique. We further extend our analysis to simulations of three-dimensional shocks undergoing more complicated dynamics, such as shock ripple, to demonstrate the ability to recover the phase space signatures of this energization process in a more general system. This work thus extends previous applications of the FPC technique to more realistic collisionless shock environments, providing stronger evidence of the technique's utility for simulation, laboratory, and spacecraft analysis. △ Less

Submitted 28 November, 2022; originally announced November 2022.

Comments: 9 pages, 5 figures

Simulation of DNA damage using Geant4-DNA: an overview of the "molecularDNA" example application

Authors: Konstantinos P. Chatzipapas, Ngoc Hoang Tran, Milos Dordevic, Sara Zivkovic, Sara Zein, Wook Geun Shin, Dousatsu Sakata, Nathanael Lampe, Jeremy M. C. Brown, Aleksandra Ristic-Fira, Ivan Petrovic, Ioanna Kyriakou, Dimitris Emfietzoglou, Susanna Guatelli, Sébastien Incerti

Abstract: The scientific community shows a great interest in the study of DNA damage induction, DNA damage repair and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in-silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4-DNA example application, named "molecularDNA", publicly release… ▽ More The scientific community shows a great interest in the study of DNA damage induction, DNA damage repair and the biological effects on cells and cellular systems after exposure to ionizing radiation. Several in-silico methods have been proposed so far to study these mechanisms using Monte Carlo simulations. This study outlines a Geant4-DNA example application, named "molecularDNA", publicly released in the 11.1 version of Geant4 (December 2022). It was developed for novice Geant4 users and requires only a basic understanding of scripting languages to get started. The example currently proposes two different DNA-scale geometries of biological targets, namely "cylinders", and the "human cell". This public version is based on a previous prototype and includes new features such as: the adoption of a new approach for the modeling of the chemical stage (IRT-sync), the use of the Standard DNA Damage (SDD) format to describe radiation-induced DNA damage and upgraded computational tools to estimate DNA damage response. Simulation data in terms of single strand break (SSB) and double strand break (DSB) yields were produced using each of these geometries. The results were compared to the literature, to validate the example, producing less than 5 % difference in all cases. △ Less

Submitted 20 March, 2023; v1 submitted 4 October, 2022; originally announced October 2022.

Comments: 20 pages, 8 figures

Report number: hal-03987017

Journal ref: Prec.Radiat.Oncol. (2023) 1- 11

Multiple Coulomb Scattering of muons in Lithium Hydride

Authors: M. Bogomilov, R. Tsenov, G. Vankova-Kirilova, Y. P. Song, J. Y. Tang, Z. H. Li, R. Bertoni, M. Bonesini, F. Chignoli, R. Mazza, V. Palladino, A. de Bari, D. Orestano, L. Tortora, Y. Kuno, H. Sakamoto, A. Sato, S. Ishimoto, M. Chung, C. K. Sung, F. Filthaut, M. Fedorov, D. Jokovic, D. Maletic, M. Savic , et al. (112 additional authors not shown)

Abstract: Multiple Coulomb Scattering (MCS) is a well known phenomenon occurring when charged particles traverse materials. Measurements of muons traversing low $Z$ materials made in the MuScat experiment showed that theoretical models and simulation codes, such as GEANT4 (v7.0), over-estimated the scattering. The Muon Ionization Cooling Experiment (MICE) measured the cooling of a muon beam traversing a liq… ▽ More Multiple Coulomb Scattering (MCS) is a well known phenomenon occurring when charged particles traverse materials. Measurements of muons traversing low $Z$ materials made in the MuScat experiment showed that theoretical models and simulation codes, such as GEANT4 (v7.0), over-estimated the scattering. The Muon Ionization Cooling Experiment (MICE) measured the cooling of a muon beam traversing a liquid hydrogen or lithium hydride (LiH) energy absorber as part of a programme to develop muon accelerator facilities, such as a Neutrino Factory or a Muon Collider. The energy loss and MCS that occur in the absorber material are competing effects that alter the performance of the cooling channel. Therefore measurements of MCS are required in order to validate the simulations used to predict the cooling performance in future accelerator facilities. We report measurements made in the MICE apparatus of MCS using a LiH absorber and muons within the momentum range 160 to 245 MeV/c. The measured RMS scattering width is about 9% smaller than that predicted by the approximate formula proposed by the Particle Data Group. Data at 172, 200 and 240 MeV/c are compared to the GEANT4 (v9.6) default scattering model. These measurements show agreement with this more recent GEANT4 (v9.6) version over the range of incident muon momenta. △ Less

Submitted 21 September, 2022; originally announced September 2022.

Comments: 20 pages, 14 figures, journal

Report number: RAL-P-2022-001

Very-high- and ultrahigh- frequency electric field detection using high angular momentum Rydberg states

Authors: Roger C. Brown, Baran Kayim, Michael A. Viray, Abigail R. Perry, Brian C. Sawyer, Robert Wyllie

Abstract: We demonstrate resonant detection of rf electric fields from 240 MHz to 900 MHz (very-high-frequency (VHF) to ultra-high-frequency (UHF)) using electromagnetically induced transparency to measure orbital angular momentum $L=3\rightarrow L'=4$ Rydberg transitions. These Rydberg states are accessible with three-photon infrared optical excitation. By resonantly detecting rf in the electrically small… ▽ More We demonstrate resonant detection of rf electric fields from 240 MHz to 900 MHz (very-high-frequency (VHF) to ultra-high-frequency (UHF)) using electromagnetically induced transparency to measure orbital angular momentum $L=3\rightarrow L'=4$ Rydberg transitions. These Rydberg states are accessible with three-photon infrared optical excitation. By resonantly detecting rf in the electrically small regime, these states enable a new class of atomic receivers. We find good agreement between measured spectra and predictions of quantum defect theory for principal quantum numbers $n=45$ to $70$. Using a super-hetrodyne detection setup, we measure the noise floor at $n=50$ to be $13\,\mathrm{μV/m/\sqrt{Hz}}$. Additionally, we utilize data and a numerical model incorporating a five-level master equation solution to estimate the fundamental sensitivity limits of our system. △ Less

Submitted 19 May, 2023; v1 submitted 25 May, 2022; originally announced May 2022.

Comments: 8 pages, 5 figures, copy edited

Journal ref: Phys. Rev. A 107, 052605 (2023)

SINR: Deconvolving Circular SAS Images Using Implicit Neural Representations

Authors: Albert Reed, Thomas Blanford, Daniel C. Brown, Suren Jayasuriya

Abstract: Circular Synthetic aperture sonars (CSAS) capture multiple observations of a scene to reconstruct high-resolution images. We can characterize resolution by modeling CSAS imaging as the convolution between a scene's underlying point scattering distribution and a system-dependent point spread function (PSF). The PSF is a function of the transmitted waveform's bandwidth and determines a fixed degree… ▽ More Circular Synthetic aperture sonars (CSAS) capture multiple observations of a scene to reconstruct high-resolution images. We can characterize resolution by modeling CSAS imaging as the convolution between a scene's underlying point scattering distribution and a system-dependent point spread function (PSF). The PSF is a function of the transmitted waveform's bandwidth and determines a fixed degree of blurring on reconstructed imagery. In theory, deconvolution overcomes bandwidth limitations by reversing the PSF-induced blur and recovering the scene's scattering distribution. However, deconvolution is an ill-posed inverse problem and sensitive to noise. We propose a self-supervised pipeline (does not require training data) that leverages an implicit neural representation (INR) for deconvolving CSAS images. We highlight the performance of our SAS INR pipeline, which we call SINR, by implementing and comparing to existing deconvolution methods. Additionally, prior SAS deconvolution methods assume a spatially-invariant PSF, which we demonstrate yields subpar performance in practice. We provide theory and methods to account for a spatially-varying CSAS PSF, and demonstrate that doing so enables SINR to achieve superior deconvolution performance on simulated and real acoustic SAS data. We provide code to encourage reproducibility of research. △ Less

Submitted 16 October, 2022; v1 submitted 21 April, 2022; originally announced April 2022.

A new Standard DNA damage (SDD) data format

Authors: J. Schuemann, A. McNamara, J. W. Warmenhoven, N. T. Henthorn, K. Kirkby, M. J. Merchant, S. Ingram, H. Paganetti, KD. Held, J. Ramos-Mendez, B. Faddegon, J. Perl, D. Goodhead, I. Plante, H. Rabus, H. Nettelbeck, W. Friedland, P. Kundrat, A. Ottolenghi, G. Baiocco, S. Barbieri, M. Dingfelder, S. Incerti, C. Villagrasa, M. Bueno , et al. (26 additional authors not shown)

Abstract: Our understanding of radiation induced cellular damage has greatly improved over the past decades. Despite this progress, there are still many obstacles to fully understanding how radiation interacts with biologically relevant cellular components to form observable endpoints. One hurdle is the difficulty faced by members of different research groups in directly comparing results. Multiple Monte Ca… ▽ More Our understanding of radiation induced cellular damage has greatly improved over the past decades. Despite this progress, there are still many obstacles to fully understanding how radiation interacts with biologically relevant cellular components to form observable endpoints. One hurdle is the difficulty faced by members of different research groups in directly comparing results. Multiple Monte Carlo codes have been developed to simulate damage induction at the DNA scale, while at the same time various groups have developed models that describe DNA repair processes with varying levels of detail. These repair models are intrinsically linked to the damage model employed in their development, making it difficult to disentangle systematic effects in either part of the modelling chain. The modelling chain typically consists of track structure Monte Carlo simulations of the physics interactions creating direct damages to the DNA; followed by simulations of the production and initial reactions of chemical species causing indirect damages. After the DNA damage induction, DNA repair models combine the simulated damage patterns with biological models to determine the biological consequences of the damage. We propose a new Standard data format for DNA Damage to unify the interface between the simulation of damage induction and the biological modelling of cell repair processes. Such a standard greatly facilitates inter model comparisons, providing an ideal environment to tease out model assumptions and identify persistent, underlying mechanisms. Through inter model comparisons, this unified standard has the potential to greatly advance our understanding of the underlying mechanisms of radiation induced DNA damage and the resulting observable biological effects. △ Less

Submitted 11 January, 2022; originally announced January 2022.

Journal ref: Radiation Research, 191(1): 76-92

Superfluid Helium Drops Levitated in High Vacuum

Authors: C. D. Brown, Y. Wang, M. Namazi, G. I. Harris, M. T. Uysal, J. G. E. Harris

Abstract: We demonstrate the trapping of millimeter-scale superfluid Helium drops in high vacuum. The drops are sufficiently isolated that they remain trapped indefinitely, cool by evaporation to 330 mK, and exhibit mechanical damping that is limited by internal processes. The drops are also shown to host optical whispering gallery modes. The approach described here combines the advantages of multiple techn… ▽ More We demonstrate the trapping of millimeter-scale superfluid Helium drops in high vacuum. The drops are sufficiently isolated that they remain trapped indefinitely, cool by evaporation to 330 mK, and exhibit mechanical damping that is limited by internal processes. The drops are also shown to host optical whispering gallery modes. The approach described here combines the advantages of multiple techniques, and should offer access to new experimental regimes of cold chemistry, superfluid physics, and optomechanics. △ Less

Submitted 31 January, 2023; v1 submitted 12 September, 2021; originally announced September 2021.

Enhancing spin polarization using ultrafast angular streaking

Authors: Gregory S. J. Armstrong, Daniel D. A. Clarke, Jakub Benda, Jack Wragg, Andrew C. Brown, Hugo W. van der Hart

Abstract: Through solution of the multielectron, semi-relativistic, time-dependent Schrödinger equation, we show that angular streaking produces strongly spin-polarized electrons in a noble gas. The degree of spin polarization increases with the Keldysh parameter, so that angular streaking -- ordinarily applied to investigate tunneling -- may be repurposed to generate strongly spin-polarized electron bunche… ▽ More Through solution of the multielectron, semi-relativistic, time-dependent Schrödinger equation, we show that angular streaking produces strongly spin-polarized electrons in a noble gas. The degree of spin polarization increases with the Keldysh parameter, so that angular streaking -- ordinarily applied to investigate tunneling -- may be repurposed to generate strongly spin-polarized electron bunches. Additionally, we explore modifications of the angular streaking scheme that also enhance spin polarization. △ Less

Submitted 30 August, 2021; originally announced August 2021.

Journal ref: Phys. Rev. A 103, 053123 (2021)

Performance of the MICE diagnostic system

Authors: The MICE collaboration, M. Bogomilov, R. Tsenov, G. Vankova-Kirilova, Y. P. Song, J. Y. Tang, Z. H. Li, R. Bertoni, M. Bonesini, F. Chignoli, R. Mazza, V. Palladino, A. de Bari, D. Orestano, L. Tortora, Y. Kuno, H. Sakamoto, A. Sato, S. Ishimoto, M. Chung, C. K. Sung, F. Filthaut, M. Fedorov, D. Jokovic, D. Maletic , et al. (113 additional authors not shown)

Abstract: Muon beams of low emittance provide the basis for the intense, well-characterised neutrino beams of a neutrino factory and for multi-TeV lepton-antilepton collisions at a muon collider. The international Muon Ionization Cooling Experiment (MICE) has demonstrated the principle of ionization cooling, the technique by which it is proposed to reduce the phase-space volume occupied by the muon beam at… ▽ More Muon beams of low emittance provide the basis for the intense, well-characterised neutrino beams of a neutrino factory and for multi-TeV lepton-antilepton collisions at a muon collider. The international Muon Ionization Cooling Experiment (MICE) has demonstrated the principle of ionization cooling, the technique by which it is proposed to reduce the phase-space volume occupied by the muon beam at such facilities. This paper documents the performance of the detectors used in MICE to measure the muon-beam parameters, and the physical properties of the liquid hydrogen energy absorber during running. △ Less

Submitted 16 August, 2021; v1 submitted 10 June, 2021; originally announced June 2021.

Comments: 27 pages, 18 figures

Report number: RAL-P-2021-001

Journal ref: 2021 JINST 16 P08046

Human Brain Mapping with Multi-Thousand Channel PtNRGrids Resolves Novel Spatiotemporal Dynamics

Authors: Youngbin Tchoe, Andrew M. Bourhis, Daniel R. Cleary, Brittany Stedelin, Jihwan Lee, Karen J. Tonsfeldt, Erik C. Brown, Dominic Siler, Angelique C. Paulk, Jimmy C. Yang, Hongseok Oh, Yun Goo Ro, Woojin Choi, Keundong Lee, Samantha Russman, Mehran Ganji, Ian Galton, Sharona Ben-Haim, Ahmed M. Raslan, Shadi A. Dayeh

Abstract: Electrophysiological devices are critical for mapping eloquent and diseased brain regions and for therapeutic neuromodulation in clinical settings and are extensively utilized for research in brain-machine interfaces. However, the existing devices are often limited in either spatial resolution or cortical coverage, even including those with thousands of channels used in animal experiments. Here, w… ▽ More Electrophysiological devices are critical for mapping eloquent and diseased brain regions and for therapeutic neuromodulation in clinical settings and are extensively utilized for research in brain-machine interfaces. However, the existing devices are often limited in either spatial resolution or cortical coverage, even including those with thousands of channels used in animal experiments. Here, we developed scalable manufacturing processes and dense connectorization to achieve reconfigurable thin-film, multi-thousand channel neurophysiological recording grids using platinum-nanorods (PtNRGrids). With PtNRGrids, we have achieved a multi-thousand channel array of small (30 μm) contacts with low impedance, providing unparalleled spatial and temporal resolution over a large cortical area. We demonstrate that PtNRGrids can resolve sub-millimeter functional organization of the barrel cortex in anesthetized rats that captured the histochemically-demonstrated structure. In the clinical setting, PtNRGrids resolved fine, complex temporal dynamics from the cortical surface in an awake human patient performing grasping tasks. Additionally, the PtNRGrids identified the spatial spread and dynamics of epileptic discharges in a patient undergoing epilepsy surgery at 1 mm spatial resolution, including activity induced by direct electrical stimulation. Collectively, these findings demonstrate the power of the PtNRGrids to transform clinical mapping and research with brain-machine interfaces and highlights a path toward novel therapeutics. △ Less

Submitted 19 August, 2021; v1 submitted 16 March, 2021; originally announced March 2021.

Comments: Main manuscript: 28 pages, 5 figures, Supporting information: 63 pages, 41 figures

An electromagnetic physics constructor for low energy polarised X-/gamma ray transport in Geant4

Authors: Jeremy M. C. Brown, Matthew R. Dimmock

Abstract: The production, application, and/or measurement of polarised X-/gamma rays are key to the fields of synchrotron science and X-/gamma-ray astronomy. The design, development and optimisation of experimental equipment utilised in these fields typically relies on the use of Monte Carlo radiation transport modelling toolkits such as Geant4. In this work the Geant4 "G4LowEPPhysics" electromagnetic physi… ▽ More The production, application, and/or measurement of polarised X-/gamma rays are key to the fields of synchrotron science and X-/gamma-ray astronomy. The design, development and optimisation of experimental equipment utilised in these fields typically relies on the use of Monte Carlo radiation transport modelling toolkits such as Geant4. In this work the Geant4 "G4LowEPPhysics" electromagnetic physics constructor has been reconfigured to offer a "best set" of electromagnetic physics models for studies exploring the transport of low energy polarised X-/gamma rays. An overview of the physics models implemented in "G4LowEPPhysics", and it's experimental validation against Compton X-ray polarimetry measurements of the BL38B1 beamline at the SPring-8 synchrotron (Sayo, Japan) is reported. "G4LowEPPhysics" is shown to be able to reproduce the experimental results obtained at the BL38B1 beamline (SPring-8) to within a level of accuracy on the same order as Geant4's X-/gamma ray interaction cross-sectional data uncertainty (approximately $\pm$ 5 \%). △ Less

Submitted 6 February, 2021; v1 submitted 4 February, 2021; originally announced February 2021.

Comments: Geant4, Polarized gamma ray, Compton scattering, X-ray astronomy, Gamma-ray astronomy, Synchrotron radiation facility

QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy

Authors: Glyn Nelson, Ulrike Boehm, Steve Bagley, Peter Bajcsy, Johanna Bischof, Claire M Brown, Aurelien Dauphin, Ian M Dobbie, John E Eriksson, Orestis Faklaris, Julia Fernandez-Rodriguez, Alexia Ferrand, Laurent Gelman, Ali Gheisari, Hella Hartmann, Christian Kukat, Alex Laude, Miso Mitkovski, Sebastian Munck, Alison J North, Tobias M Rasse, Ute Resch-Genger, Lucas C Schuetz, Arne Seitz, Caterina Strambio-De-Castillia , et al. (75 additional authors not shown)

Abstract: In April 2020, the QUality Assessment and REProducibility for Instruments and Images in Light Microscopy (QUAREP-LiMi) initiative was formed. This initiative comprises imaging scientists from academia and industry who share a common interest in achieving a better understanding of the performance and limitations of microscopes and improved quality control (QC) in light microscopy. The ultimate goal… ▽ More In April 2020, the QUality Assessment and REProducibility for Instruments and Images in Light Microscopy (QUAREP-LiMi) initiative was formed. This initiative comprises imaging scientists from academia and industry who share a common interest in achieving a better understanding of the performance and limitations of microscopes and improved quality control (QC) in light microscopy. The ultimate goal of the QUAREP-LiMi initiative is to establish a set of common QC standards, guidelines, metadata models, and tools, including detailed protocols, with the ultimate aim of improving reproducible advances in scientific research. This White Paper 1) summarizes the major obstacles identified in the field that motivated the launch of the QUAREP-LiMi initiative; 2) identifies the urgent need to address these obstacles in a grassroots manner, through a community of stakeholders including, researchers, imaging scientists, bioimage analysts, bioimage informatics developers, corporate partners, funding agencies, standards organizations, scientific publishers, and observers of such; 3) outlines the current actions of the QUAREP-LiMi initiative, and 4) proposes future steps that can be taken to improve the dissemination and acceptance of the proposed guidelines to manage QC. To summarize, the principal goal of the QUAREP-LiMi initiative is to improve the overall quality and reproducibility of light microscope image data by introducing broadly accepted standard practices and accurately captured image data metrics. △ Less

Submitted 27 January, 2021; v1 submitted 21 January, 2021; originally announced January 2021.

Comments: 17 pages, 3 figures, shortened abstract, Co-Lead Authors: Glyn Nelson and Ulrike Boehm, Corresponding author: Roland Nitschke

Journal ref: J. Microsc. 2021;1-18

Full field X-ray Scatter Tomography

Authors: Gary Ruben, Isaac Pinar, Jeremy M. C. Brown, Florian Schaff, James A. Pollock, Kelly J. Crossley, Anton Maksimenko, Chris Hall, Daniel Hausermann, Kentaro Uesugi, Marcus J. Kitchen

Abstract: In X-ray imaging, photons are transmitted through and absorbed by the subject, but are also scattered in significant quantities. Previous attempts to use scattered photons for biological imaging used pencil or fan beam illumination. Here we present 3D X-ray Scatter Tomography using full-field illumination. Synchrotron imaging experiments were performed of a phantom and the chest of a juvenile rat.… ▽ More In X-ray imaging, photons are transmitted through and absorbed by the subject, but are also scattered in significant quantities. Previous attempts to use scattered photons for biological imaging used pencil or fan beam illumination. Here we present 3D X-ray Scatter Tomography using full-field illumination. Synchrotron imaging experiments were performed of a phantom and the chest of a juvenile rat. Transmitted and scattered photons were simultaneously imaged with separate cameras; a scientific camera directly downstream of the sample stage, and a pixelated detector with a pinhole imaging system placed at 45${}^\circ$ to the beam axis. We obtained scatter tomogram feature fidelity sufficient for segmentation of the lung and major airways in the rat. The image contrast in scatter tomogram slices approached that of transmission imaging, indicating robustness to the amount of multiple scattering present in our case. This opens the possibility of augmenting full-field 2D imaging systems with additional scatter detectors to obtain complementary modes or to improve the fidelity of existing images without additional dose, potentially leading to single-shot or reduced-angle tomography or overall dose reduction for live animal studies. △ Less

Submitted 10 March, 2022; v1 submitted 16 December, 2020; originally announced December 2020.

Comments: 11 pages, 6 figures, Accepted for publication in IEEE Transactions on Medical Imaging

Neural network-based on-chip spectroscopy using a scalable plasmonic encoder

Authors: Calvin Brown, Artem Goncharov, Zachary Ballard, Mason Fordham, Ashley Clemens, Yunzhe Qiu, Yair Rivenson, Aydogan Ozcan

Abstract: Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip sensing scheme that is not constrained by the design trade-offs inherent to grating-based spectroscopy. The system employs a plasmonic spectral encoder chip co… ▽ More Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip sensing scheme that is not constrained by the design trade-offs inherent to grating-based spectroscopy. The system employs a plasmonic spectral encoder chip containing 252 different tiles of nanohole arrays fabricated using a scalable and low-cost imprint lithography method, where each tile has a unique geometry and, thus, a unique optical transmission spectrum. The illumination spectrum of interest directly impinges upon the plasmonic encoder, and a CMOS image sensor captures the transmitted light, without any lenses, gratings, or other optical components in between, making the entire hardware highly compact, light-weight and field-portable. A trained neural network then reconstructs the unknown spectrum using the transmitted intensity information from the spectral encoder in a feed-forward and non-iterative manner. Benefiting from the parallelization of neural networks, the average inference time per spectrum is ~28 microseconds, which is orders of magnitude faster compared to other computational spectroscopy approaches. When blindly tested on unseen new spectra (N = 14,648) with varying complexity, our deep-learning based system identified 96.86% of the spectral peaks with an average peak localization error, bandwidth error, and height error of 0.19 nm, 0.18 nm, and 7.60%, respectively. This system is also highly tolerant to fabrication defects that may arise during the imprint lithography process, which further makes it ideal for applications that demand cost-effective, field-portable and sensitive high-resolution spectroscopy tools. △ Less

Submitted 1 December, 2020; originally announced December 2020.

Comments: 18 pages, 6 figures

Journal ref: ACS Nano (2021)

Manipulating Twisted Electrons in Strong-Field Ionization

Authors: A. S. Maxwell, G. S. J. Armstrong, M. F. Ciappina, E. Pisanty, Y. Kang, A. C. Brown, M. Lewenstein, C. Figueira de Morisson Faria

Abstract: We investigate the discrete orbital angular momentum (OAM) of photoelectrons freed in strongfield ionization. We use these `twisted' electrons to provide an alternative interpretation on existing experimental work of vortex interferences caused by strong field ionization mediated by two counterrotating circularly polarized pulses separated by a delay. Using the strong field approximation, we deriv… ▽ More We investigate the discrete orbital angular momentum (OAM) of photoelectrons freed in strongfield ionization. We use these `twisted' electrons to provide an alternative interpretation on existing experimental work of vortex interferences caused by strong field ionization mediated by two counterrotating circularly polarized pulses separated by a delay. Using the strong field approximation, we derive an interference condition for the vortices. In computations for a neon target we find very good agreement of the vortex condition with photoelectron momentum distributions computed with the strong field approximation, as well as with the time-dependent methods Qprop and R-Matrix. For each of these approaches we examine the OAM of the photoelectrons, finding a small number of vortex states localized in separate energy regions. We demonstrate that the vortices arise from the interference of pairs of twisted electron states. The OAM of each twisted electron state can be directly related to the number of arms of the spiral in that region. We gain further understanding by recreating the vortices with pairs of twisted electrons and use this to determine a semiclassical relation for the OAM. A discussion is included on measuring the OAM in strong field ionization directly or by employing specific laser pulse schemes as well as utilizing the OAM in time-resolved imaging of photo-induced dynamics. △ Less

Submitted 16 October, 2020; originally announced October 2020.

Comments: 14 pages, 4 figures, publication prepared for the the strong field theme of the Faraday Discussions conference: Time-resolved imaging of photo-induced dynamics

Journal ref: Faraday Discussions 228, 394 (2021)

Formation of Argon Cluster with Proton Seeding

Authors: O. C. F. Brown, D. Vrinceanu, V. Kharchenk, H. R. Sadeghpour

Abstract: We employ force-field molecular dynamics simulations to investigate the kinetics of nucleation to new liquid or solid phases in a dense gas of particles, seeded with ions. We use precise atomic pair interactions, with physically correct long-range behavior, between argon atoms and protons. Time-dependence of molecular cluster formation is analyzed at different proton concentration, temperature and… ▽ More We employ force-field molecular dynamics simulations to investigate the kinetics of nucleation to new liquid or solid phases in a dense gas of particles, seeded with ions. We use precise atomic pair interactions, with physically correct long-range behavior, between argon atoms and protons. Time-dependence of molecular cluster formation is analyzed at different proton concentration, temperature and argon gas density. The modified phase transitions with proton seeding of the argon gas are identified and analyzed. The seeding of the gas enhances the formation of nano-size atomic clusters and their aggregation. The strong attraction between protons and bath gas atoms stabilizes large nano-clusters and the critical temperature for evaporation. An analytical model is proposed to describe the stability of argon-proton droplets, and is compared with the molecular dynamics simulations. △ Less

Submitted 4 August, 2020; originally announced August 2020.

Comments: 10 pages, 6 figures

Journal ref: Molecular Physics, e1767813 (2020)

Volumetric heating of nanowire arrays to keV temperatures using kilojoule-scale petawatt laser interactions

Authors: M. P. Hill, O. Humphries, R. Royle, B. Williams, M. G. Ramsay, A. Miscampbell, P. Allan, C. R. D. Brown, L. M. R. Hobbs, S. F. James, D. J. Hoarty, R. S. Marjoribanks, J. Park, R. A. London, R. Tommasini, A. Pukhov, C. Bargsten, R. Hollinger, V. N. Shlyaptsev, M. G. Capeluto, J. J. Rocca, S. M. Vinko

Abstract: We present picosecond-resolution streaked K-shell spectra from 400 nm-diameter nickel nanowire arrays, demonstrating the ability to generate large volumes of high energy density plasma when combined with the longer pulses typical of the largest short pulse lasers. After irradiating the wire array with 100 J, 600 fs ultra-high-contrast laser pulses focussed to $>10^{20}$ W/cm$^{2}$ at the Orion las… ▽ More We present picosecond-resolution streaked K-shell spectra from 400 nm-diameter nickel nanowire arrays, demonstrating the ability to generate large volumes of high energy density plasma when combined with the longer pulses typical of the largest short pulse lasers. After irradiating the wire array with 100 J, 600 fs ultra-high-contrast laser pulses focussed to $>10^{20}$ W/cm$^{2}$ at the Orion laser facility, we combine atomic kinetics modeling of the streaked spectra with 2D collisional particle-in-cell simulations to describe the evolution of material conditions within these samples for the first time. We observe a three-fold enhancement of helium-like emission compared to a flat foil in a near-solid-density plasma sustaining keV temperatures for tens of picoseconds, the result of strong electric return currents heating the wires and causing them to explode and collide. △ Less

Submitted 20 July, 2020; originally announced July 2020.

Comments: 5 pages, 5 figures

Interaction-Enhanced Group Velocity of Bosons in the Flat Band of an Optical Kagome Lattice

Authors: Tsz-Him Leung, Malte N. Schwarz, Shao-Wen Chang, Charles D. Brown, Govind Unnikrishnan, Dan Stamper-Kurn

Abstract: Geometric frustration of particle motion in a kagome lattice causes the single-particle band structure to have a flat s-orbital band. We probe this band structure by exciting a Bose-Einstein condensate into excited Bloch states of an optical kagome lattice, and then measuring the group velocity through the atomic momentum distribution. We find that interactions renormalize the band structure of th… ▽ More Geometric frustration of particle motion in a kagome lattice causes the single-particle band structure to have a flat s-orbital band. We probe this band structure by exciting a Bose-Einstein condensate into excited Bloch states of an optical kagome lattice, and then measuring the group velocity through the atomic momentum distribution. We find that interactions renormalize the band structure of the kagome lattice, greatly increasing the dispersion of the third band that, according to non-interacting band theory, should be nearly non-dispersing. Measurements at various lattice depths and gas densities agree quantitatively with predictions of the lattice Gross-Pitaevskii equation, indicating that the observed distortion of band structure is caused by the disortion of the overall lattice potential away from the kagome geometry by interactions. △ Less

Submitted 12 July, 2020; originally announced July 2020.

Journal ref: Phys. Rev. Lett. 125, 133001 (2020)

Polarization control of high-harmonic generation via the spin-orbit interaction

Authors: Jack Wragg, Daniel D. A. Clarke, Gregory S. J. Armstrong, Andrew C. Brown, Connor P. Ballance, Hugo W. van der Hart

Abstract: We observe the generation of high harmonics in the plane perpendicular to the driving laser polarization and show that these are driven by the spin-orbit interaction. Using R-Matrix with time-dependence theory, we demonstrate that for certain initial states either circularly- or linearly- polarized harmonics arise via well-known selection rules between atomic states controlled by the spin-orbit in… ▽ More We observe the generation of high harmonics in the plane perpendicular to the driving laser polarization and show that these are driven by the spin-orbit interaction. Using R-Matrix with time-dependence theory, we demonstrate that for certain initial states either circularly- or linearly- polarized harmonics arise via well-known selection rules between atomic states controlled by the spin-orbit interaction. Finally, we elucidate the connection between the observed harmonics and the phase of the intial state. △ Less

Submitted 22 June, 2020; originally announced June 2020.

Comments: 5 pages, 5 figures

An Automated, Cost-Effective Optical System for Accelerated Anti-microbial Susceptibility Testing (AST) using Deep Learning

Authors: Calvin Brown, Derek Tseng, Paige M. K. Larkin, Susan Realegeno, Leanne Mortimer, Arjun Subramonian, Dino Di Carlo, Omai B. Garner, Aydogan Ozcan

Abstract: Antimicrobial susceptibility testing (AST) is a standard clinical procedure used to quantify antimicrobial resistance (AMR). Currently, the gold standard method requires incubation for 18-24 h and subsequent inspection for growth by a trained medical technologist. We demonstrate an automated, cost-effective optical system that delivers early AST results, minimizing incubation time and eliminating… ▽ More Antimicrobial susceptibility testing (AST) is a standard clinical procedure used to quantify antimicrobial resistance (AMR). Currently, the gold standard method requires incubation for 18-24 h and subsequent inspection for growth by a trained medical technologist. We demonstrate an automated, cost-effective optical system that delivers early AST results, minimizing incubation time and eliminating human errors, while remaining compatible with standard phenotypic assay workflow. The system is composed of cost-effective components and eliminates the need for optomechanical scanning. A neural network processes the captured optical intensity information from an array of fiber optic cables to determine whether bacterial growth has occurred in each well of a 96-well microplate. When the system was blindly tested on isolates from 33 patients with Staphylococcus aureus infections, 95.03% of all the wells containing growth were correctly identified using our neural network, with an average of 5.72 h of incubation time required to identify growth. 90% of all wells (growth and no-growth) were correctly classified after 7 h, and 95% after 10.5 h. Our deep learning-based optical system met the FDA-defined criteria for essential and categorical agreements for all 14 antibiotics tested after an average of 6.13 h and 6.98 h, respectively. Furthermore, our system met the FDA criteria for major and very major error rates for 11 of 12 possible drugs after an average of 4.02 h, and 9 of 13 possible drugs after an average of 9.39 h, respectively. This system could enable faster, inexpensive, automated AST, especially in resource limited settings, helping to mitigate the rise of global AMR. △ Less

Submitted 22 May, 2020; originally announced May 2020.

Comments: 13 Pages, 6 Figures, 1 Table

Journal ref: ACS Photonics (2020)

Modeling motional energy spectra and lattice light shifts in optical lattice clocks

Authors: K. Beloy, W. F. McGrew, X. Zhang, D. Nicolodi, R. J. Fasano, Y. S. Hassan, R. C. Brown, A. D. Ludlow

Abstract: We develop a model to describe the motional (i.e., external degree of freedom) energy spectra of atoms trapped in a one-dimensional optical lattice, taking into account both axial and radial confinement relative to the lattice axis. Our model respects the coupling between axial and radial degrees of freedom, as well as other anharmonicities inherent in the confining potential. We further demonstra… ▽ More We develop a model to describe the motional (i.e., external degree of freedom) energy spectra of atoms trapped in a one-dimensional optical lattice, taking into account both axial and radial confinement relative to the lattice axis. Our model respects the coupling between axial and radial degrees of freedom, as well as other anharmonicities inherent in the confining potential. We further demonstrate how our model can be used to characterize lattice light shifts in optical lattice clocks, including shifts due to higher multipolar (magnetic dipole and electric quadrupole) and higher order (hyperpolarizability) coupling to the lattice field. We compare results for our model with results from other lattice light shift models in the literature under similar conditions. △ Less

Submitted 13 April, 2020; originally announced April 2020.

Comments: 19 pages; accepted to PRA

Journal ref: Phys. Rev. A 101, 053416 (2020)

Electron correlation and short-range dynamics in attosecond angular streaking

Authors: G. S. J. Armstrong, D. D. A. Clarke, J. Benda, A. C. Brown, H. W. van der Hart

Abstract: We employ the R-matrix with time-dependence method to study attosecond angular streaking of F$^-$. Using this negative ion, free of long-range Coulomb interactions, we elucidate the role of short-range electron correlation effects in an attoclock scheme. Through solution of the multielectron time-dependent Schrodinger equation, we aim to bridge the gap between experiments using multielectron targe… ▽ More We employ the R-matrix with time-dependence method to study attosecond angular streaking of F$^-$. Using this negative ion, free of long-range Coulomb interactions, we elucidate the role of short-range electron correlation effects in an attoclock scheme. Through solution of the multielectron time-dependent Schrodinger equation, we aim to bridge the gap between experiments using multielectron targets, and one-electron theoretical approaches. We observe significant negative offset angles in the photoelectron momentum distributions, despite the short-range nature of the binding potential. We show that the offset angle is sensitive to the atomic structure description of the residual F atom. We also investigate the response of co- and counter-rotating electrons, and observe an angular separation in their emission. △ Less

Submitted 27 March, 2020; originally announced March 2020.