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Computer Science > Computer Vision and Pattern Recognition

arXiv:2510.20095 (cs)
[Submitted on 23 Oct 2025 (v1), last revised 1 Mar 2026 (this version, v3)]

Title:BioCAP: Exploiting Synthetic Captions Beyond Labels in Biological Foundation Models

Authors:Ziheng Zhang, Xinyue Ma, Arpita Chowdhury, Elizabeth G. Campolongo, Matthew J. Thompson, Net Zhang, Samuel Stevens, Hilmar Lapp, Tanya Berger-Wolf, Yu Su, Wei-Lun Chao, Jianyang Gu
View a PDF of the paper titled BioCAP: Exploiting Synthetic Captions Beyond Labels in Biological Foundation Models, by Ziheng Zhang and 11 other authors
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Abstract:This work investigates descriptive captions as an additional source of supervision for biological multimodal foundation models. Images and captions can be viewed as complementary samples from the latent morphospace of a species, each capturing certain biological traits. Incorporating captions during training encourages alignment with this shared latent structure, emphasizing potentially diagnostic characters while suppressing spurious correlations. The main challenge, however, lies in obtaining faithful, instance-specific captions at scale. This requirement has limited the utilization of natural language supervision in organismal biology compared with many other scientific domains. We complement this gap by generating synthetic captions with multimodal large language models (MLLMs), guided by Wikipedia-derived visual information and taxon-tailored format examples. These domain-specific contexts help reduce hallucination and yield accurate, instance-based descriptive captions. Using these captions, we train BioCAP (i.e., BioCLIP with Captions), a biological foundation model that captures rich semantics and achieves strong performance in species classification and text-image retrieval. These results demonstrate the value of descriptive captions beyond labels in bridging biological images with multimodal foundation models.
Comments: ICLR 2026; Project page: this https URL
Subjects: Computer Vision and Pattern Recognition (cs.CV); Computation and Language (cs.CL); Machine Learning (cs.LG)
Cite as: arXiv:2510.20095 [cs.CV]
  (or arXiv:2510.20095v3 [cs.CV] for this version)
  https://doi.org/10.48550/arXiv.2510.20095
arXiv-issued DOI via DataCite

Submission history

From: Ziheng Zhang [view email]
[v1] Thu, 23 Oct 2025 00:34:21 UTC (14,596 KB)
[v2] Fri, 24 Oct 2025 01:51:09 UTC (14,580 KB)
[v3] Sun, 1 Mar 2026 19:26:07 UTC (14,695 KB)
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