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Gemini 2.5: Pushing the Frontier with Advanced Reasoning, Multimodality, Long Context, and Next Generation Agentic Capabilities
Authors:
Gheorghe Comanici,
Eric Bieber,
Mike Schaekermann,
Ice Pasupat,
Noveen Sachdeva,
Inderjit Dhillon,
Marcel Blistein,
Ori Ram,
Dan Zhang,
Evan Rosen,
Luke Marris,
Sam Petulla,
Colin Gaffney,
Asaf Aharoni,
Nathan Lintz,
Tiago Cardal Pais,
Henrik Jacobsson,
Idan Szpektor,
Nan-Jiang Jiang,
Krishna Haridasan,
Ahmed Omran,
Nikunj Saunshi,
Dara Bahri,
Gaurav Mishra,
Eric Chu
, et al. (3410 additional authors not shown)
Abstract:
In this report, we introduce the Gemini 2.X model family: Gemini 2.5 Pro and Gemini 2.5 Flash, as well as our earlier Gemini 2.0 Flash and Flash-Lite models. Gemini 2.5 Pro is our most capable model yet, achieving SoTA performance on frontier coding and reasoning benchmarks. In addition to its incredible coding and reasoning skills, Gemini 2.5 Pro is a thinking model that excels at multimodal unde…
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In this report, we introduce the Gemini 2.X model family: Gemini 2.5 Pro and Gemini 2.5 Flash, as well as our earlier Gemini 2.0 Flash and Flash-Lite models. Gemini 2.5 Pro is our most capable model yet, achieving SoTA performance on frontier coding and reasoning benchmarks. In addition to its incredible coding and reasoning skills, Gemini 2.5 Pro is a thinking model that excels at multimodal understanding and it is now able to process up to 3 hours of video content. Its unique combination of long context, multimodal and reasoning capabilities can be combined to unlock new agentic workflows. Gemini 2.5 Flash provides excellent reasoning abilities at a fraction of the compute and latency requirements and Gemini 2.0 Flash and Flash-Lite provide high performance at low latency and cost. Taken together, the Gemini 2.X model generation spans the full Pareto frontier of model capability vs cost, allowing users to explore the boundaries of what is possible with complex agentic problem solving.
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Submitted 19 December, 2025; v1 submitted 7 July, 2025;
originally announced July 2025.
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Closing the AI generalization gap by adjusting for dermatology condition distribution differences across clinical settings
Authors:
Rajeev V. Rikhye,
Aaron Loh,
Grace Eunhae Hong,
Preeti Singh,
Margaret Ann Smith,
Vijaytha Muralidharan,
Doris Wong,
Rory Sayres,
Michelle Phung,
Nicolas Betancourt,
Bradley Fong,
Rachna Sahasrabudhe,
Khoban Nasim,
Alec Eschholz,
Basil Mustafa,
Jan Freyberg,
Terry Spitz,
Yossi Matias,
Greg S. Corrado,
Katherine Chou,
Dale R. Webster,
Peggy Bui,
Yuan Liu,
Yun Liu,
Justin Ko
, et al. (1 additional authors not shown)
Abstract:
Recently, there has been great progress in the ability of artificial intelligence (AI) algorithms to classify dermatological conditions from clinical photographs. However, little is known about the robustness of these algorithms in real-world settings where several factors can lead to a loss of generalizability. Understanding and overcoming these limitations will permit the development of generali…
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Recently, there has been great progress in the ability of artificial intelligence (AI) algorithms to classify dermatological conditions from clinical photographs. However, little is known about the robustness of these algorithms in real-world settings where several factors can lead to a loss of generalizability. Understanding and overcoming these limitations will permit the development of generalizable AI that can aid in the diagnosis of skin conditions across a variety of clinical settings. In this retrospective study, we demonstrate that differences in skin condition distribution, rather than in demographics or image capture mode are the main source of errors when an AI algorithm is evaluated on data from a previously unseen source. We demonstrate a series of steps to close this generalization gap, requiring progressively more information about the new source, ranging from the condition distribution to training data enriched for data less frequently seen during training. Our results also suggest comparable performance from end-to-end fine tuning versus fine tuning solely the classification layer on top of a frozen embedding model. Our approach can inform the adaptation of AI algorithms to new settings, based on the information and resources available.
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Submitted 23 February, 2024;
originally announced February 2024.
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MINT: A wrapper to make multi-modal and multi-image AI models interactive
Authors:
Jan Freyberg,
Abhijit Guha Roy,
Terry Spitz,
Beverly Freeman,
Mike Schaekermann,
Patricia Strachan,
Eva Schnider,
Renee Wong,
Dale R Webster,
Alan Karthikesalingam,
Yun Liu,
Krishnamurthy Dvijotham,
Umesh Telang
Abstract:
During the diagnostic process, doctors incorporate multimodal information including imaging and the medical history - and similarly medical AI development has increasingly become multimodal. In this paper we tackle a more subtle challenge: doctors take a targeted medical history to obtain only the most pertinent pieces of information; how do we enable AI to do the same? We develop a wrapper method…
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During the diagnostic process, doctors incorporate multimodal information including imaging and the medical history - and similarly medical AI development has increasingly become multimodal. In this paper we tackle a more subtle challenge: doctors take a targeted medical history to obtain only the most pertinent pieces of information; how do we enable AI to do the same? We develop a wrapper method named MINT (Make your model INTeractive) that automatically determines what pieces of information are most valuable at each step, and ask for only the most useful information. We demonstrate the efficacy of MINT wrapping a skin disease prediction model, where multiple images and a set of optional answers to $25$ standard metadata questions (i.e., structured medical history) are used by a multi-modal deep network to provide a differential diagnosis. We show that MINT can identify whether metadata inputs are needed and if so, which question to ask next. We also demonstrate that when collecting multiple images, MINT can identify if an additional image would be beneficial, and if so, which type of image to capture. We showed that MINT reduces the number of metadata and image inputs needed by 82% and 36.2% respectively, while maintaining predictive performance. Using real-world AI dermatology system data, we show that needing fewer inputs can retain users that may otherwise fail to complete the system submission and drop off without a diagnosis. Qualitative examples show MINT can closely mimic the step-by-step decision making process of a clinical workflow and how this is different for straight forward cases versus more difficult, ambiguous cases. Finally we demonstrate how MINT is robust to different underlying multi-model classifiers and can be easily adapted to user requirements without significant model re-training.
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Submitted 22 January, 2024;
originally announced January 2024.
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AI system for fetal ultrasound in low-resource settings
Authors:
Ryan G. Gomes,
Bellington Vwalika,
Chace Lee,
Angelica Willis,
Marcin Sieniek,
Joan T. Price,
Christina Chen,
Margaret P. Kasaro,
James A. Taylor,
Elizabeth M. Stringer,
Scott Mayer McKinney,
Ntazana Sindano,
George E. Dahl,
William Goodnight III,
Justin Gilmer,
Benjamin H. Chi,
Charles Lau,
Terry Spitz,
T Saensuksopa,
Kris Liu,
Jonny Wong,
Rory Pilgrim,
Akib Uddin,
Greg Corrado,
Lily Peng
, et al. (4 additional authors not shown)
Abstract:
Despite considerable progress in maternal healthcare, maternal and perinatal deaths remain high in low-to-middle income countries. Fetal ultrasound is an important component of antenatal care, but shortage of adequately trained healthcare workers has limited its adoption. We developed and validated an artificial intelligence (AI) system that uses novice-acquired "blind sweep" ultrasound videos to…
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Despite considerable progress in maternal healthcare, maternal and perinatal deaths remain high in low-to-middle income countries. Fetal ultrasound is an important component of antenatal care, but shortage of adequately trained healthcare workers has limited its adoption. We developed and validated an artificial intelligence (AI) system that uses novice-acquired "blind sweep" ultrasound videos to estimate gestational age (GA) and fetal malpresentation. We further addressed obstacles that may be encountered in low-resourced settings. Using a simplified sweep protocol with real-time AI feedback on sweep quality, we have demonstrated the generalization of model performance to minimally trained novice ultrasound operators using low cost ultrasound devices with on-device AI integration. The GA model was non-inferior to standard fetal biometry estimates with as few as two sweeps, and the fetal malpresentation model had high AUC-ROCs across operators and devices. Our AI models have the potential to assist in upleveling the capabilities of lightly trained ultrasound operators in low resource settings.
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Submitted 18 March, 2022;
originally announced March 2022.