Extracellular vesicles miRNA-21: a potential therapeutic tool in premature ovarian dysfunction

E Thabet, A Yusuf, DA Abdelmonsif… - Molecular Human …, 2020 - academic.oup.com
Chemotherapy induces an irreversible premature ovarian dysfunction (POD). Amniotic fluid
mesenchymal stem cells (AFMSCs) can rescue fertility; however, the notion that stem cells …

Pitavastatin-loaded bilosomes for oral treatment of hepatocellular carcinoma: A repurposing approach

M Kharouba, A El-Kamel, R Mehanna, E Thabet… - Drug Delivery, 2022 - Taylor & Francis
Albeit its established efficacy as an anti-hyperlipidemic agent, pitavastatin (PIT) has been
shown to have other various therapeutic effects. One of these effects is the anti-cancer activity …

Antibiotic-induced gut microbe dysbiosis alters neurobehavior in mice through modulation of BDNF and gut integrity

E Thabet, AE Dief, SAF Arafa, D Yakout, MA Ali - Physiology & behavior, 2024 - Elsevier
Gut microbiota is essential for intestinal integrity and brain functions. Herein we aimed to
investigate the effects of alteration of gut microbiome using broad-spectrum antibiotics on CD 1 …

Role of biological data mining and machine learning techniques in detecting and diagnosing the novel coronavirus (COVID-19): a systematic review

…, AH AlAmoodi, JM Khlaf, EM Almahdi, E Thabet… - Journal of medical …, 2020 - Springer
Coronaviruses (CoVs) are a large family of viruses that are common in many animal species,
including camels, cattle, cats and bats. Animal CoVs, such as Middle East respiratory …

Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus

…, D El-Lebedy, EH Thabet - Clinical Medicine …, 2013 - journals.sagepub.com
Renal tubulointerstitium plays an important role in the development and progression of
diabetic nephropathy. The aim of this study was to assess serum cystatin C and 2 renal tubular …

Chitosan-coated bovine serum albumin nanoparticles for topical tetrandrine delivery in glaucoma: in vitro and in vivo assessment

…, RM El-Moslemany, RA Mehanna, EH Thabet… - Drug Delivery, 2022 - Taylor & Francis
Glaucoma is one of the leading causes of blindness. Therapies available suffer from several
drawbacks including low bioavailability, repeated administration and poor patient …

Early prediction of liver carcinogenicity due to occupational exposure to pesticides

…, W Shaheen, EA Abdel-Shafy, E Thabet - … /Genetic Toxicology and …, 2019 - Elsevier
Several studies linked between pesticides exposure and development of liver cancer, through
several mechanisms inform of genotoxicity, cytotoxicity, tumor promotion, immunotoxicity …

Co-culture strategies for muscle–fat tissue development from caprine satellite cells: a step toward sustainable cultivated meat

T Elhaddad, E Thabet, MM Essawy, AM Embaby… - Food Research …, 2025 - Elsevier
Cultivated meat offers a sustainable alternative to conventional livestock production, yet
caprine species remain underexplored. This study investigates the bipotential differentiation …

Cardiac stem cells: Current knowledge and future prospects

…, MA Barkat, AK Awaad, EH Thabet… - World journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Regenerative medicine is the field concerned with the repair and restoration of the integrity
of damaged human tissues as well as whole organs. Since the inception of the field several …

Biochemical investigation and in Silico analysis of the therapeutic efficacy of Ipriflavone through Tet-1 Surface-Modified-PLGA nanoparticles in Streptozotocin-Induced …

…, SN Khattab, E Sheta, FY Elnozahy, EH Thabet… - International Journal of …, 2025 - Elsevier
Ipriflavone (IPRI), an isoflavone derivative, is clinically used to prevent postmenopausal
bone loss in addition to its antioxidant and cognitive benefits. However, its poor aqueous …