User profiles for Yang Zhang
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The I-TASSER Suite: protein structure and function prediction
To the Editor: Assignment of structure and function to all genes and gene products (such as
proteins) of all organisms represents a major challenge in this postgenomic era. Here we …
proteins) of all organisms represents a major challenge in this postgenomic era. Here we …
Circular intronic long noncoding RNAs
We describe the identification and characterization of circular intronic long noncoding RNAs
in human cells, which accumulate owing to a failure in debranching. The formation of such …
in human cells, which accumulate owing to a failure in debranching. The formation of such …
I-TASSER server for protein 3D structure prediction
Y Zhang - BMC bioinformatics, 2008 - Springer
Background Prediction of 3-dimensional protein structures from amino acid sequences
represents one of the most important problems in computational structural biology. The …
represents one of the most important problems in computational structural biology. The …
Deepseek-r1: Incentivizing reasoning capability in llms via reinforcement learning
General reasoning represents a long-standing and formidable challenge in artificial
intelligence. Recent breakthroughs, exemplified by large language models (LLMs) and chain-of-…
intelligence. Recent breakthroughs, exemplified by large language models (LLMs) and chain-of-…
I-TASSER server: new development for protein structure and function predictions
The I-TASSER server ( http://zhanglab.ccmb.med.umich.edu/I-TASSER ) is an online resource
for automated protein structure prediction and structure-based function annotation. In I-…
for automated protein structure prediction and structure-based function annotation. In I-…
I-TASSER: a unified platform for automated protein structure and function prediction
The iterative threading assembly refinement (I-TASSER) server is an integrated platform for
automated protein structure and function prediction based on the sequence-to-structure-to-…
automated protein structure and function prediction based on the sequence-to-structure-to-…
Protein structure and function prediction using I‐TASSER
I‐TASSER is a hierarchical protocol for automated protein structure prediction and structure‐based
function annotation. Starting from the amino acid sequence of target proteins, I‐…
function annotation. Starting from the amino acid sequence of target proteins, I‐…
Analyze the psychological impact of COVID-19 among the elderly population in China and make corresponding suggestions
…, Y Xu, J Dai, Y Zhang, B Liu, H Yang - Psychiatry …, 2020 - pmc.ncbi.nlm.nih.gov
… Haibo Yang conceived the idea for the Article. Hui Meng, Jiali Dai, Yang Zhang, Yang Xu
and Baogeng Liu … Yang Xu amended the manuscript and gave suggestions for data analysis. …
and Baogeng Liu … Yang Xu amended the manuscript and gave suggestions for data analysis. …
Deepseek-v3 technical report
We present DeepSeek-V3, a strong Mixture-of-Experts (MoE) language model with 671B
total parameters with 37B activated for each token. To achieve efficient inference and cost-…
total parameters with 37B activated for each token. To achieve efficient inference and cost-…
DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning
General reasoning represents a long-standing and formidable challenge in artificial intelligence
(AI). Recent breakthroughs, exemplified by large language models (LLMs) 1 , 2 and …
(AI). Recent breakthroughs, exemplified by large language models (LLMs) 1 , 2 and …