User profiles for "author:Haeussler M"

Maximilian Haeussler

Research Scientist, UC Santa Cruz Genomics Institute
Verified email at ucsc.edu
Cited by 36848

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR

M Haeussler, K Schönig, H Eckert, A Eschstruth… - Genome biology, 2016 - Springer
Background The success of the CRISPR/Cas9 genome editing technique depends on the
choice of the guide RNA sequence, which is facilitated by various websites. Despite the …

The UCSC genome browser database: 2025 update

G Perez, GP Barber, A Benet-Pages… - Nucleic acids …, 2025 - academic.oup.com
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is a widely utilized web-
based tool for visualization and analysis of genomic data, encompassing over 4000 …

The UCSC genome browser database: 2019 update

M Haeussler, AS Zweig, C Tyner, ML Speir… - Nucleic acids …, 2019 - academic.oup.com
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is a graphical viewer for
exploring genome annotations. For almost two decades, the Browser has provided …

The UCSC genome browser database: 2023 update

LR Nassar, GP Barber, A Benet-Pagès… - Nucleic acids …, 2023 - academic.oup.com
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is an omics data
consolidator, graphical viewer, and general bioinformatics resource that continues to serve …

The UCSC genome browser database: 2015 update

KR Rosenbloom, J Armstrong, GP Barber… - Nucleic acids …, 2015 - academic.oup.com
Launched in 2001 to showcase the draft human genome assembly, the UCSC Genome
Browser database (http://genome. ucsc. edu) and associated tools continue to grow …

CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens

JP Concordet, M Haeussler - Nucleic acids research, 2018 - academic.oup.com
CRISPOR. org is a web tool for genome editing experiments with the CRISPR–Cas9 system.
It finds guide RNAs in an input sequence and ranks them according to different scores that …

The UCSC Genome Browser database: extensions and updates 2013

LR Meyer, AS Zweig, AS Hinrichs… - Nucleic acids …, 2012 - academic.oup.com
Abstract The University of California Santa Cruz (UCSC) Genome Browser (http://genome.
ucsc. edu) offers online public access to a growing database of genomic sequence and …

[HTML][HTML] Spatial epigenome–transcriptome co-profiling of mammalian tissues

D Zhang, Y Deng, P Kukanja, E Agirre, M Bartosovic… - Nature, 2023 - nature.com
Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics,
are becoming powerful tools for profiling of cellular states in the tissue context,,,–. However …

Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex

TJ Nowakowski, A Bhaduri, AA Pollen, B Alvarado… - Science, 2017 - science.org
Systematic analyses of spatiotemporal gene expression trajectories during organogenesis
have been challenging because diverse cell types at different stages of maturation and …

The UCSC genome browser database: 2014 update

D Karolchik, GP Barber, J Casper… - Nucleic acids …, 2014 - academic.oup.com
Abstract The University of California Santa Cruz (UCSC) Genome Browser (http://genome.
ucsc. edu) offers online public access to a growing database of genomic sequence and …