The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have
been sampled to date in the form of expressed sequence tags. An international consortium …

C57BL/6J (B6) and DBA/2J (D2) are two of the most commonly used inbred mouse strains in
neuroscience research. However, the only currently available mouse genome is based …

It is well established that chronic heavy alcohol drinking (CHD) results in significant organ
damage, increased susceptibility to infections, and poor outcomes following injury. In …

Evidence for genetic linkage to alcohol and other substance dependence phenotypes in
areas of the human and mouse genome have now been reported with some consistency …

Aldosterone regulates electrolyte and fluid homeostasis through binding to the
mineralocorticoid receptors (MRs). Previous work provides evidence for a role of …

Prenatal alcohol exposure (PAE), like other pregnancy complications, can result in placental
insufficiency and fetal growth restriction, although the linking causal mechanisms are …

Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine,
octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated …

Physiological dependence and associated withdrawal episodes can constitute a powerful
motivational force that perpetuates drug use and abuse. Using robust behavioral models of …

Here, we map a quantitative trait locus (QTL) with a large effect on predisposition to
barbiturate (pentobarbital) withdrawal to a 0.44 Mb interval of mouse chromosome 1 …

Background The Monkey Alcohol Tissue Research Resource (MATRR) is a repository and
analytics platform for detailed data derived from well‐documented nonhuman primate (NHP) …