User profiles for "author:Gentleman R"
Robert GentlemanPrincipal Research Scientist Verified email at ds.dfci.harvard.edu Cited by 85135 |
Orchestrating high-throughput genomic analysis with Bioconductor
Bioconductor is an open-source, open-development software project for the analysis and
comprehension of high-throughput data in genomics and molecular biology. The project …
comprehension of high-throughput data in genomics and molecular biology. The project …
[BOOK][B] Bioinformatics and computational biology solutions using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the
analysis and comprehension of data arising from high-throughput experimentation in …
analysis and comprehension of data arising from high-throughput experimentation in …
Open source software for the analysis of microarray data
DNA microarray assays represent the first widely used application that attempts to build
upon the information provided by genome projects in the study of biological questions. One …
upon the information provided by genome projects in the study of biological questions. One …
[BOOK][B] R programming for bioinformatics
R Gentleman - 2008 - books.google.com
Focusing on the programming skills needed to use R for the solution of bioinformatics and
computational biology problems, this practical guide covers the fundamentals of the R …
computational biology problems, this practical guide covers the fundamentals of the R …
Graphs in molecular biology
W Huber, VJ Carey, L Long, S Falcon, R Gentleman - BMC bioinformatics, 2007 - Springer
Graph theoretical concepts are useful for the description and analysis of interactions and
relationships in biological systems. We give a brief introduction into some of the concepts …
relationships in biological systems. We give a brief introduction into some of the concepts …
Circulating microRNAs as stable blood-based markers for cancer detection
PS Mitchell, RK Parkin, EM Kroh, BR Fritz… - Proceedings of the …, 2008 - pnas.org
Improved approaches for the detection of common epithelial malignancies are urgently
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs …
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs …
Bioconductor: open software development for computational biology and bioinformatics
RC Gentleman, VJ Carey, DM Bates, B Bolstad… - Genome biology, 2004 - Springer
The Bioconductor project is an initiative for the collaborative creation of extensible software
for computational biology and bioinformatics. The goals of the project include: fostering …
for computational biology and bioinformatics. The goals of the project include: fostering …
R: a language for data analysis and graphics
R Ihaka, R Gentleman - Journal of computational and graphical …, 1996 - Taylor & Francis
In this article we discuss our experience designing and implementing a statistical computing
language. In developing this new language, we sought to combine what we felt were useful …
language. In developing this new language, we sought to combine what we felt were useful …
rtracklayer: an R package for interfacing with genome browsers
M Lawrence, R Gentleman, V Carey - Bioinformatics, 2009 - pmc.ncbi.nlm.nih.gov
The rtracklayer package supports the integration of existing genome browsers with
experimental data analyses performed in R. The user may (i) transfer annotation tracks to …
experimental data analyses performed in R. The user may (i) transfer annotation tracks to …
A model-based background adjustment for oligonucleotide expression arrays
High-density oligonucleotide expression arrays are widely used in many areas of
biomedical research. Affymetrix GeneChip arrays are the most popular. In the Affymetrix …
biomedical research. Affymetrix GeneChip arrays are the most popular. In the Affymetrix …