Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8

RP Searles, EP Bergquam, MK Axthelm… - Journal of …, 1999 - journals.asm.org
We have sequenced the long unique region (LUR) and characterized the terminal repeats of
the genome of a rhesus rhadinovirus (RRV), strain 17577. The LUR as sequenced is …

Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays

D Bottomly, NAR Walter, JE Hunter, P Darakjian… - PloS one, 2011 - journals.plos.org
C57BL/6J (B6) and DBA/2J (D2) are two of the most commonly used inbred mouse strains in
neuroscience research. However, the only currently available mouse genome is based …

[HTML][HTML] Vault ribonucleoprotein particles from rat and bullfrog contain a related small RNA that is transcribed by RNA polymerase III.

VA Kickhoefer, RP Searles, NL Kedersha… - Journal of Biological …, 1993 - Elsevier
Vaults are large cytoplasmic ribonucleoprotein particles with a sedimentation value of about
150 S. These particles contain a unique small RNA (vault RNA (vRNA)). We have …

[HTML][HTML] Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology …

SA Mantey, HC Weber, E Sainz, M Akeson… - Journal of Biological …, 1997 - Elsevier
An orphan receptor discovered in 1993 was called bombesin receptor subtype 3 (BRS-3)
because of 47–51% amino acid identity with bombesin (Bn) receptors. Its pharmacology is …

The prevalence of anticardiolipin antibodies in a healthy elderly population and its association with antinuclear antibodies.

RA Fields, H Toubbeh, RP Searles… - The Journal of …, 1989 - europepmc.org
The presence of anticardiolipin antibodies (aCL) has been associated with arterial and
venous thrombotic events in connective tissue diseases. Previous investigations have …

Chromatin clearance in C57Bl/10 mice: interaction with heparan sulphate proteoglycans and receptors on Kupffer cells

TW Du Clos, MA Volzer, FF Hahn, R Xiao… - Clinical & …, 1999 - academic.oup.com
Chromatin is an important autoantigen in the pathogenesis of systemic lupus erythematosus
(SLE) as an immunogen and as a part of nephritogenic immune complexes. Earlier studies …

Immunological responses of healthy elderly population

JS Goodwin, RP Searles… - Clinical and experimental …, 1982 - pmc.ncbi.nlm.nih.gov
We measured in vitro mitogen responses, delayed hypersensitivity skin tests, circulating
immune complexes (CIC) and three autoantibodies in 279 healthy and 24 chronically ill …

Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies

BU Orzechowska, MF Powers… - Blood, The Journal …, 2008 - ashpublications.org
Rhesus macaque rhadinovirus (RRV) is closely related to Kaposi sarcoma-associated
herpesvirus (KSHV) and is associated with the development of B-cell hyperplasia and …

[HTML][HTML] Molecular cloning and expression of the rat beta 1-adrenergic receptor gene.

CA Machida, JR Bunzow, RP Searles, H Van Tol… - Journal of Biological …, 1990 - Elsevier
Using the sequence homology approach for cloning related genes within the G-protein-
coupled receptor gene family, we have cloned the gene for the rat beta 1-adrenergic …

Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity

YJ Alharithi, EA Phillips, TD Wilson… - American Journal …, 2025 - journals.physiology.org
Maternal obesity puts the offspring at high risk of developing obesity and cardiometabolic
diseases in adulthood. Here, we utilized a mouse model of maternal high-fat diet (HFD) …