This paper surveys approaches to the discovery of patterns in biosequences and places
these approaches within a formal framework that systematises the types of patterns and the …

We present a new method for the identification of conserved patterns in a set of unaligned
related protein sequences. It is able to discover patterns of a quite general form, allowing for …

Signature databases are vital tools for identifying distant relationships in novel sequences
and hence for inferring protein function. InterPro is an integrated documentation resource for …

The whole-genome duplication 80 million years ago of the common ancestor of salmonids
(salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique …

In recent years, analogs of human insulin have been engineered with the aim of improving
therapy for people with diabetes. To ensure that the safety profile of the human hormone is …

Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing
commercial fisheries and incipient aquaculture,. Here we present the genome sequence of …

Albumin is a multifunctional transport protein that binds a wide variety of endogenous
substances and drugs. Insulins with affinity for albumin were engineered by acylation of the …

High throughput sequencing technology has great promise for biodiversity studies.
However, an underlying assumption is that the primers used in these studies are universal …

Motivation: We have previously reported an algorithm for discovering patterns conserved in
sets of related unaligned protein sequences. The algorithm was implemented in a program …

Biomarkers are of great importance in many fields, such as cancer research, toxicology,
diagnosis and treatment of diseases, and to better understand biological response …