User profiles for Haswanth Vundavilli

Haswanth Vundavilli, Ph.D.

Assistant Professor, IIT (ISM), Dhanbad, India
Verified email at iitism.ac.in
Cited by 313

In silico design and experimental validation of combination therapy for pancreatic cancer

H Vundavilli, A Datta, C Sima, J Hua… - … ACM transactions on …, 2018 - ieeexplore.ieee.org
The number of deaths associated with Pancreatic Cancer has been on the rise in the United
States making it an especially dreaded disease. The overall prognosis for pancreatic cancer …

Bayesian inference identifies combination therapeutic targets in breast cancer

H Vundavilli, A Datta, C Sima, J Hua… - IEEE Transactions …, 2019 - ieeexplore.ieee.org
Objective: Breast cancer is the second leading cause of cancer death among US women;
hence, identifying potential drug targets is an ever increasing need. In this paper, we integrate …

Advancements in hybrid machine learning models for biomedical disease classification using integration of hyperparameter-tuning and feature selection …

…, A Sharma, A Kumar, S Maini, H Vundavilli - … Methods in Engineering, 2026 - Springer
This systematic review presents a comprehensive analysis of hybrid optimization frameworks
that combine hyperparameter-tuning and feature selection to enhance machine learning (…

Advances in machine learning and deep learning for hormonal disorder diagnosis: an exhaustive review on PCOS, thyroid, and optimization techniques

S Dhanka, A Kumar, A Sharma, H Vundavilli… - … Methods in Engineering, 2026 - Springer
Hormonal disorders like Polycystic Ovary Syndrome (PCOS), thyroid dysfunction, and
diabetes pose significant diagnostic challenges due to their complex etiology and overlapping …

Targeting oncogenic mutations in colorectal cancer using cryptotanshinone

H Vundavilli, A Datta, C Sima, J Hua, R Lopes… - PLoS …, 2021 - journals.plos.org
Colorectal cancer (CRC) is one of the most prevalent types of cancer in the world and ranks
second in cancer deaths in the US. Despite the recent improvements in screening and …

Drug target identification in triple negative breast cancer stem cell pathways: A computational study of gene regulatory pathways using Boolean networks

A Lahiri, H Vundavilli, M Mondal, P Bhattacharjee… - IEEE …, 2023 - ieeexplore.ieee.org
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer associated with
an early age of onset, greater propensity towards metastasis, and poorer clinical outcomes. …

Anti-tumor effects of cryptotanshinone (C19H20O3) in human osteosarcoma cell lines

H Vundavilli, A Datta, C Sima, J Hua, R Lopes… - Biomedicine & …, 2022 - Elsevier
Osteosarcoma is the most prevalent malignant bone tumor and occurs most commonly in
the adolescent and young adult population. Despite the recent advances in surgeries and …

A computational study of efficient combinations of FDA-approved drugs and dietary supplements in endometrial cancer

M Mondal, A Lahiri, H Vundavilli, G Del Priore… - IEEE …, 2024 - ieeexplore.ieee.org
Endometrial cancer (EC) develops in the uterine lining, and in 2024, there will be approximately
67,880 reported cases of uterine cancer in the USA, with 90% of them being EC. Many …

A modular trial of androgen signaling inhibitor combinations testing a risk-adapted strategy in patients with metastatic castration–resistant prostate cancer

…, S Guo, PG Pilié, Y Yu, X Song, H Vundavilli… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: To determine the efficacy and safety of risk-adapted combinations of androgen
signaling inhibitors and inform disease classifiers for metastatic castration–resistant prostate …

Integrative network modeling highlights the crucial roles of Rho-GDI signaling pathway in the progression of non-small cell lung cancer

S Gupta, H Vundavilli, RSA Osorio… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer and a leading
cause of cancer-related deaths worldwide. Using an integrative approach, we analyzed a …