{"id":"https://openalex.org/W2112750506","doi":"https://doi.org/10.3389/fncom.2010.00152","title":"Postsynaptic Signal Transduction Models for Long-Term Potentiation and Depression","display_name":"Postsynaptic Signal Transduction Models for Long-Term Potentiation and Depression","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2112750506","doi":"https://doi.org/10.3389/fncom.2010.00152","mag":"2112750506","pmid":"https://pubmed.ncbi.nlm.nih.gov/21188161"},"language":"en","primary_location":{"id":"doi:10.3389/fncom.2010.00152","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2010.00152","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2010.00152/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncom.2010.00152/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037580924","display_name":"Tiina Manninen","orcid":"https://orcid.org/0000-0002-0456-1185"},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Tiina Manninen","raw_affiliation_strings":["Department of Signal Processing, Tampere University of Technology Tampere, Finland","Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Signal Processing, Tampere University of Technology Tampere, Finland","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4210133110"]},{"raw_affiliation_string":"Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#","institution_ids":["https://openalex.org/I4210133110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017795556","display_name":"Katri Hituri","orcid":null},"institutions":[{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Katri Hituri","raw_affiliation_strings":["Tampere University of Technology, Department of Signal Processing, Tampere, Finland","Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tampere University of Technology, Department of Signal Processing, Tampere, Finland","institution_ids":["https://openalex.org/I4210133110"]},{"raw_affiliation_string":"Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#","institution_ids":["https://openalex.org/I4210133110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084813027","display_name":"Jeanette Hellgren Kotaleski","orcid":"https://orcid.org/0000-0002-0550-0739"},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I86987016","display_name":"KTH Royal Institute of Technology","ror":"https://ror.org/026vcq606","country_code":"SE","type":"education","lineage":["https://openalex.org/I86987016"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jeanette Hellgren Kotaleski","raw_affiliation_strings":["School of Computer Science and Communication , Royal Institute of Technology , Stockholm , Sweden","Stockholm Brain Institute , Karolinska Institutet , Stockholm , Sweden","Karolinska Institutet, Stockholm Brain Institute, Stockholm, Sweden","Royal Institute of Technology, School of Computer Science and Communication, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Communication , Royal Institute of Technology , Stockholm , Sweden","institution_ids":["https://openalex.org/I86987016"]},{"raw_affiliation_string":"Stockholm Brain Institute , Karolinska Institutet , Stockholm , Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Karolinska Institutet, Stockholm Brain Institute, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Royal Institute of Technology, School of Computer Science and Communication, Stockholm, Sweden","institution_ids":["https://openalex.org/I86987016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054745889","display_name":"Kim T. Blackwell","orcid":"https://orcid.org/0000-0003-4711-2344"},"institutions":[{"id":"https://openalex.org/I162714631","display_name":"George Mason University","ror":"https://ror.org/02jqj7156","country_code":"US","type":"education","lineage":["https://openalex.org/I162714631"]},{"id":"https://openalex.org/I40036882","display_name":"Institute for Advanced Study","ror":"https://ror.org/00f809463","country_code":"US","type":"facility","lineage":["https://openalex.org/I40036882"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim T. Blackwell","raw_affiliation_strings":["George Mason University, Krasnow Institute for Advanced Study, Fairfax, United States","George mason university, krasnow institute for advanced study, fairfax, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"George Mason University, Krasnow Institute for Advanced Study, Fairfax, United States","institution_ids":["https://openalex.org/I162714631","https://openalex.org/I40036882"]},{"raw_affiliation_string":"George mason university, krasnow institute for advanced study, fairfax, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008868538","display_name":"Marja\u2010Leena Linne","orcid":"https://orcid.org/0000-0003-2577-7329"},"institutions":[{"id":"https://openalex.org/I4210133110","display_name":"Tampere University","ror":null,"country_code":"FI","type":null,"lineage":["https://openalex.org/I4210133110"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Marja-Leena Linne","raw_affiliation_strings":["Tampere University of Technology, Department of Signal Processing, Tampere, Finland","Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tampere University of Technology, Department of Signal Processing, Tampere, Finland","institution_ids":["https://openalex.org/I4210133110"]},{"raw_affiliation_string":"Tampere University of Technology, Dept. of Signal Processing, Tampere, Finland#TAB#","institution_ids":["https://openalex.org/I4210133110"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5037580924"],"corresponding_institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4210133110"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":1.988,"has_fulltext":true,"cited_by_count":53,"citation_normalized_percentile":{"value":0.85641419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"4","issue":null,"first_page":"152","last_page":"152"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-term-potentiation","display_name":"Long-term potentiation","score":0.8508473634719849},{"id":"https://openalex.org/keywords/postsynaptic-potential","display_name":"Postsynaptic potential","score":0.7395524978637695},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6499955058097839},{"id":"https://openalex.org/keywords/term","display_name":"Term (time)","score":0.6184710264205933},{"id":"https://openalex.org/keywords/long-term-depression","display_name":"Long-term depression","score":0.5763079524040222},{"id":"https://openalex.org/keywords/depression","display_name":"Depression (economics)","score":0.5183723568916321},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.4950770437717438},{"id":"https://openalex.org/keywords/post-tetanic-potentiation","display_name":"Post-tetanic potentiation","score":0.47398486733436584},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.45948728919029236},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.2987588346004486},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.23864531517028809},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.23840385675430298},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23130008578300476},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.17131584882736206},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.15777486562728882},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1465432345867157},{"id":"https://openalex.org/keywords/glutamate-receptor","display_name":"Glutamate receptor","score":0.1062217652797699},{"id":"https://openalex.org/keywords/economics","display_name":"Economics","score":0.10602971911430359},{"id":"https://openalex.org/keywords/ampa-receptor","display_name":"AMPA receptor","score":0.0704730749130249}],"concepts":[{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.8508473634719849},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7395524978637695},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6499955058097839},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.6184710264205933},{"id":"https://openalex.org/C73009533","wikidata":"https://www.wikidata.org/wiki/Q1517140","display_name":"Long-term depression","level":5,"score":0.5763079524040222},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5183723568916321},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.4950770437717438},{"id":"https://openalex.org/C118232355","wikidata":"https://www.wikidata.org/wiki/Q7233588","display_name":"Post-tetanic potentiation","level":4,"score":0.47398486733436584},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.45948728919029236},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2987588346004486},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23864531517028809},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.23840385675430298},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23130008578300476},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17131584882736206},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.15777486562728882},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1465432345867157},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.1062217652797699},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.10602971911430359},{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.0704730749130249},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fncom.2010.00152","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2010.00152","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2010.00152/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},{"id":"pmid:21188161","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21188161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in computational neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3006457","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3006457","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Comput Neurosci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:907fb0e1638749a8b7971ecb5f2cd4b3","is_oa":true,"landing_page_url":"https://doaj.org/article/907fb0e1638749a8b7971ecb5f2cd4b3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Computational Neuroscience, Vol 4 (2010)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncom.2010.00152","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncom.2010.00152","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncom.2010.00152/pdf","source":{"id":"https://openalex.org/S19778766","display_name":"Frontiers in Computational Neuroscience","issn_l":"1662-5188","issn":["1662-5188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Computational Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6399999856948853,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"awards":[{"id":"https://openalex.org/G1914879260","display_name":null,"funder_award_id":"R01 AA016022","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G603611056","display_name":null,"funder_award_id":"R01-AA018060","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G8176291262","display_name":null,"funder_award_id":"R01 AA18060","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8891565954","display_name":"CRCNS: Spatio-temporal Dynamics of Dopamine Activated 2nd Messenger Pathway","funder_award_id":"5r01aa016022-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320314164","display_name":"Parkinson's Foundation","ror":"https://ror.org/005aa3k38"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322861","display_name":"Emil Aaltosen S\u00e4\u00e4ti\u00f6","ror":"https://ror.org/005rt3g54"},{"id":"https://openalex.org/F4320323337","display_name":"Tekniikan Edist\u00e4miss\u00e4\u00e4ti\u00f6","ror":"https://ror.org/03f420b93"},{"id":"https://openalex.org/F4320327840","display_name":"Otto A. Malm Lahjoitusrahasto","ror":"https://ror.org/05srazs86"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2112750506.pdf","grobid_xml":"https://content.openalex.org/works/W2112750506.grobid-xml"},"referenced_works_count":217,"referenced_works":["https://openalex.org/W19385301","https://openalex.org/W50684321","https://openalex.org/W74971858","https://openalex.org/W250910456","https://openalex.org/W602834913","https://openalex.org/W1481003809","https://openalex.org/W1504223663","https://openalex.org/W1507113656","https://openalex.org/W1564150153","https://openalex.org/W1576102240","https://openalex.org/W1781851852","https://openalex.org/W1797216850","https://openalex.org/W1821391051","https://openalex.org/W1836848727","https://openalex.org/W1872915332","https://openalex.org/W1965572014","https://openalex.org/W1967660012","https://openalex.org/W1967663642","https://openalex.org/W1968912342","https://openalex.org/W1969621260","https://openalex.org/W1970318896","https://openalex.org/W1970611142","https://openalex.org/W1971734119","https://openalex.org/W1972107254","https://openalex.org/W1974275159","https://openalex.org/W1974974415","https://openalex.org/W1976645516","https://openalex.org/W1978730538","https://openalex.org/W1978756588","https://openalex.org/W1979356066","https://openalex.org/W1980553508","https://openalex.org/W1982128084","https://openalex.org/W1983097579","https://openalex.org/W1985271644","https://openalex.org/W1986120363","https://openalex.org/W1986246844","https://openalex.org/W1986291163","https://openalex.org/W1988269419","https://openalex.org/W1988507461","https://openalex.org/W1989011685","https://openalex.org/W1993868308","https://openalex.org/W1996857341","https://openalex.org/W1999576398","https://openalex.org/W2000894573","https://openalex.org/W2002838013","https://openalex.org/W2004281064","https://openalex.org/W2006947257","https://openalex.org/W2007135500","https://openalex.org/W2007387912","https://openalex.org/W2009544901","https://openalex.org/W2009782005","https://openalex.org/W2010837985","https://openalex.org/W2010920096","https://openalex.org/W2010982767","https://openalex.org/W2011493879","https://openalex.org/W2013737562","https://openalex.org/W2016302331","https://openalex.org/W2016928899","https://openalex.org/W2017393913","https://openalex.org/W2017707236","https://openalex.org/W2017789880","https://openalex.org/W2018578596","https://openalex.org/W2018809194","https://openalex.org/W2020325647","https://openalex.org/W2020565887","https://openalex.org/W2021194717","https://openalex.org/W2021235911","https://openalex.org/W2021285984","https://openalex.org/W2022333738","https://openalex.org/W2022419428","https://openalex.org/W2023044003","https://openalex.org/W2023691991","https://openalex.org/W2025422724","https://openalex.org/W2029056405","https://openalex.org/W2030233148","https://openalex.org/W2033844584","https://openalex.org/W2035550082","https://openalex.org/W2035605861","https://openalex.org/W2036014076","https://openalex.org/W2037267760","https://openalex.org/W2038262676","https://openalex.org/W2041587312","https://openalex.org/W2042321087","https://openalex.org/W2044001483","https://openalex.org/W2046159149","https://openalex.org/W2047966157","https://openalex.org/W2049445311","https://openalex.org/W2049511526","https://openalex.org/W2050066016","https://openalex.org/W2050077524","https://openalex.org/W2050490808","https://openalex.org/W2051248457","https://openalex.org/W2057058124","https://openalex.org/W2058709617","https://openalex.org/W2059223531","https://openalex.org/W2059715474","https://openalex.org/W2060168844","https://openalex.org/W2060200435","https://openalex.org/W2060941075","https://openalex.org/W2063219876","https://openalex.org/W2064354742","https://openalex.org/W2065158671","https://openalex.org/W2066538423","https://openalex.org/W2066783383","https://openalex.org/W2066887656","https://openalex.org/W2067083029","https://openalex.org/W2067187446","https://openalex.org/W2067598670","https://openalex.org/W2067914926","https://openalex.org/W2067982358","https://openalex.org/W2068235094","https://openalex.org/W2069004234","https://openalex.org/W2071007053","https://openalex.org/W2071814535","https://openalex.org/W2071938721","https://openalex.org/W2073299285","https://openalex.org/W2074013429","https://openalex.org/W2075289911","https://openalex.org/W2077406048","https://openalex.org/W2078962021","https://openalex.org/W2079079425","https://openalex.org/W2079496755","https://openalex.org/W2081635675","https://openalex.org/W2082089816","https://openalex.org/W2082221311","https://openalex.org/W2082246938","https://openalex.org/W2082656140","https://openalex.org/W2083034329","https://openalex.org/W2084010240","https://openalex.org/W2087445908","https://openalex.org/W2087861759","https://openalex.org/W2089132727","https://openalex.org/W2090178344","https://openalex.org/W2090765114","https://openalex.org/W2092090394","https://openalex.org/W2094681580","https://openalex.org/W2095182283","https://openalex.org/W2096551329","https://openalex.org/W2096652014","https://openalex.org/W2099015579","https://openalex.org/W2100060186","https://openalex.org/W2101707733","https://openalex.org/W2102653059","https://openalex.org/W2103563062","https://openalex.org/W2103731399","https://openalex.org/W2107062718","https://openalex.org/W2109048981","https://openalex.org/W2109386884","https://openalex.org/W2110025254","https://openalex.org/W2110724392","https://openalex.org/W2113094198","https://openalex.org/W2115462216","https://openalex.org/W2115472127","https://openalex.org/W2115743992","https://openalex.org/W2117038992","https://openalex.org/W2118444707","https://openalex.org/W2119179178","https://openalex.org/W2119693160","https://openalex.org/W2121735882","https://openalex.org/W2122370921","https://openalex.org/W2122588406","https://openalex.org/W2127887898","https://openalex.org/W2130851537","https://openalex.org/W2131067724","https://openalex.org/W2131455211","https://openalex.org/W2131856835","https://openalex.org/W2133667940","https://openalex.org/W2133752887","https://openalex.org/W2133938042","https://openalex.org/W2134103459","https://openalex.org/W2134927362","https://openalex.org/W2136621137","https://openalex.org/W2138323614","https://openalex.org/W2138903241","https://openalex.org/W2139513028","https://openalex.org/W2139815948","https://openalex.org/W2141114982","https://openalex.org/W2142083285","https://openalex.org/W2142672656","https://openalex.org/W2143007771","https://openalex.org/W2144948613","https://openalex.org/W2145026073","https://openalex.org/W2146189197","https://openalex.org/W2147101007","https://openalex.org/W2147909046","https://openalex.org/W2151542182","https://openalex.org/W2154045630","https://openalex.org/W2155418451","https://openalex.org/W2157092518","https://openalex.org/W2157990975","https://openalex.org/W2158691076","https://openalex.org/W2159279126","https://openalex.org/W2160604122","https://openalex.org/W2162086511","https://openalex.org/W2164192685","https://openalex.org/W2166100493","https://openalex.org/W2167032335","https://openalex.org/W2168760377","https://openalex.org/W2172021704","https://openalex.org/W2185212694","https://openalex.org/W2258993652","https://openalex.org/W2267914923","https://openalex.org/W2274305405","https://openalex.org/W2282054059","https://openalex.org/W2327217990","https://openalex.org/W2394619739","https://openalex.org/W2462465517","https://openalex.org/W2466065712","https://openalex.org/W2486507922","https://openalex.org/W2492697853","https://openalex.org/W4214891130","https://openalex.org/W4234488249","https://openalex.org/W4235847145","https://openalex.org/W4236668382","https://openalex.org/W4238054623","https://openalex.org/W4253315667","https://openalex.org/W4301109571"],"related_works":["https://openalex.org/W1974249396","https://openalex.org/W2046705055","https://openalex.org/W2090007274","https://openalex.org/W2413063319","https://openalex.org/W4285127779","https://openalex.org/W2007715660","https://openalex.org/W1986246844","https://openalex.org/W2064319342","https://openalex.org/W2079790584","https://openalex.org/W1546859207"],"abstract_inverted_index":{"More":[0],"than":[1,66],"a":[2,50,67,221],"hundred":[3,59,68],"biochemical":[4],"species,":[5],"activated":[6],"by":[7,146],"neurotransmitters":[8],"binding":[9],"to":[10,54,93,166,199,233],"transmembrane":[11],"receptors,":[12],"are":[13,29,70,75,84,90,142,171,211,224],"important":[14],"in":[15,214,216,226],"long-term":[16,20],"potentiation":[17],"(LTP)":[18],"and":[19,27,72,77,82,105,130,174,189,230,255,264],"depression":[21],"(LTD).":[22],"To":[23],"investigate":[24],"which":[25],"species":[26],"interactions":[28],"critical":[30],"for":[31,246],"synaptic":[32,97,123,251],"plasticity,":[33],"many":[34],"computational":[35],"postsynaptic":[36],"signal":[37],"transduction":[38],"models":[39,44,48,56,69,89,118,141,164,181,206,210,223,235,245],"have":[40],"been":[41],"developed.":[42],"The":[43,88,178],"range":[45],"from":[46],"simple":[47],"with":[49,57,151,260],"single":[51],"reversible":[52],"reaction":[53],"detailed":[55],"several":[58,209],"kinetic":[60],"reactions.":[61],"In":[62],"this":[63],"study,":[64],"more":[65,85,179,261],"reviewed,":[71],"their":[73],"features":[74],"compared":[76],"contrasted":[78],"so":[79],"that":[80,99,115,140,240],"similarities":[81],"differences":[83],"readily":[86],"apparent.":[87],"classified":[91],"according":[92],"the":[94,117,120,131,202,217,241,267],"type":[95],"of":[96,122,154,160,184,192,204,243,250,266],"plasticity":[98,124,252],"is":[100,197,236,253],"modeled":[101,125],"(LTP":[102],"or":[103,110,128,136,157],"LTD)":[104],"whether":[106],"they":[107,170],"include":[108,119],"diffusion":[109,159],"electrophysiological":[111,152],"phenomena.":[112],"Other":[113],"characteristics":[114],"discriminate":[116],"phase":[121],"(induction,":[126],"expression,":[127],"maintenance)":[129],"simulation":[132],"method":[133],"used":[134],"(deterministic":[135],"stochastic).":[137],"We":[138,238],"find":[139],"becoming":[143],"increasingly":[144],"sophisticated,":[145],"including":[147],"stochastic":[148],"properties,":[149],"integrating":[150],"properties":[153,188],"entire":[155],"neurons,":[156],"incorporating":[158],"signaling":[161],"molecules.":[162],"Simpler":[163],"continue":[165],"be":[167,257],"developed":[168],"because":[169,207],"computationally":[172],"efficient":[173],"allow":[175],"theoretical":[176],"analysis.":[177],"complex":[180],"permit":[182],"investigation":[183],"mechanisms":[185,249],"underlying":[186],"specific":[187],"experimental":[190],"verification":[191],"model":[193,228],"predictions.":[194],"Nonetheless,":[195],"it":[196],"difficult":[198],"fully":[200],"comprehend":[201],"evolution":[203],"these":[205,244],"(1)":[208],"not":[212],"described":[213],"detail":[215],"publications,":[218],"(2)":[219],"only":[220],"few":[222],"provided":[225],"existing":[227],"databases,":[229],"(3)":[231],"comparison":[232],"previous":[234],"lacking.":[237],"conclude":[239],"value":[242],"understanding":[247],"molecular":[248],"increasing":[254],"will":[256],"enhanced":[258],"further":[259],"complete":[262],"descriptions":[263],"sharing":[265],"published":[268],"models.":[269]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":5}],"updated_date":"2026-08-25T07:29:55.448023","created_date":"2025-10-10T00:00:00"}